Annotation Detail for PTPLA
Basic Information Top
| Gene Symbol: | PTPLA ( CAP,HACD1 ) |
|---|---|
| Gene Full Name: | protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A |
| Band: | 10p14-p13 |
| Quick Links | Entrez ID:9200; OMIM: 610467; Uniprot ID:HACD1_HUMAN; ENSEMBL ID: ENSG00000165996; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.114062
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 7 / 564012 | 12 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 14 / 1939121 | 7 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 29 / 3360307 | 8 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 6 / 1100989 | 5 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 1 / 16212 | 61 |  |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 1 / 89626 | 11 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 4 / 210574 | 18 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 5 / 51780 | 96 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 219654_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.4 | |
| Adipocyte | 54.05 | |
| AdrenalCortex | 6.35 | |
| Adrenalgland | 4.8 | |
| Amygdala | 6.65 | |
| Appendix | 6.05 | |
| AtrioventricularNode | 4.65 | |
| BDCA4+_DentriticCells | 5.65 | |
| Bonemarrow | 5.65 | |
| BronchialEpithelialCells | 51.5 | |
| CD105+_Endothelial | 11.6 | |
| CD14+_Monocytes | 6.1 | |
| CD19+_BCells(neg._sel.) | 6.65 | |
| CD33+_Myeloid | 7 | |
| CD34+ | 143.5 | |
| CD4+_Tcells | 5.95 | |
| CD56+_NKCells | 6.65 | |
| CD71+_EarlyErythroid | 5.45 | |
| CD8+_Tcells | 5.3 | |
| CardiacMyocytes | 8.45 | |
| Caudatenucleus | 5.1 | |
| Cerebellum | 4.6 | |
| CerebellumPeduncles | 6.45 | |
| CiliaryGanglion | 4.35 | |
| CingulateCortex | 5.85 | |
| Colorectaladenocarcinoma | 5.95 | |
| DorsalRootGanglion | 4.4 | |
| FetalThyroid | 5.85 | |
| Fetalbrain | 5.65 | |
| Fetalliver | 4.95 | |
| Fetallung | 5.6 | |
| GlobusPallidus | 4.15 | |
| Heart | 65.45 | |
| Hypothalamus | 6.3 | |
| Kidney | 4.7 | |
| Leukemia_chronicMyelogenousK-562 | 4.95 | |
| Leukemia_promyelocytic-HL-60 | 5.05 | |
| Leukemialymphoblastic(MOLT-4) | 28.95 | |
| Liver | 7.6 | |
| Lung | 18.85 | |
| Lymphnode | 4.7 | |
| Lymphoma_burkitts(Daudi) | 7.5 | |
| Lymphoma_burkitts(Raji) | 8.05 | |
| MedullaOblongata | 5.2 | |
| OccipitalLobe | 5.15 | |
| OlfactoryBulb | 4.5 | |
| Ovary | 3.8 | |
| Pancreas | 4.55 | |
| PancreaticIslet | 6 | |
| ParietalLobe | 6.05 | |
| Pituitary | 6.75 | |
| Placenta | 5.75 | |
| Pons | 5.45 | |
| PrefrontalCortex | 7.1 | |
| Prostate | 20 | |
| Salivarygland | 6 | |
| SkeletalMuscle | 7.15 | |
| Skin | 4.8 | |
| SmoothMuscle | 8.15 | |
| Spinalcord | 6.05 | |
| SubthalamicNucleus | 5.2 | |
| SuperiorCervicalGanglion | 6.55 | |
| TemporalLobe | 5.2 | |
| Testis | 4.85 | |
| TestisGermCell | 5.35 | |
| TestisIntersitial | 4.85 | |
| TestisLeydigCell | 5.8 | |
| TestisSeminiferousTubule | 4.8 | |
| Thalamus | 5.8 | |
| Thymus | 4.4 | |
| Thyroid | 7.3 | |
| Tongue | 5.75 | |
| Tonsil | 5.5 | |
| Trachea | 4.75 | |
| TrigeminalGanglion | 6.4 | |
| Uterus | 10.5 | |
| UterusCorpus | 5.2 | |
| WholeBlood | 6.15 | |
| Wholebrain | 4.8 | |
| colon | 9.25 | |
| pineal_day | 7 | |
| pineal_night | 6.94 | |
| retina | 18.55 | |
| small_intestine | 5.65 | |
- Probe name: CUST_8222_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.26 ± 0.84 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.99 ± 0.61 | |
| Basal Part of Pons | 3.24 ± 0.74 | |
| Cerebellar Cortex | 3.89 ± 0.32 | |
| Cerebellar Nuclei | 3.17 ± 0.66 | |
| Claustrum | 3.16 ± 0.69 | |
| Epithalamus | 3.12 ± 0.84 | |
| Frontal Lobe | 3.55 ± 0.61 | |
| Globus Pallidus | 2.86 ± 0.85 | |
| Hypothalamus | 3.75 ± 0.54 | |
| Insula | 3.57 ± 0.35 | |
| Limbic Lobe | 3.22 ± 0.87 | |
| Mesencephalon | 3.4 ± 0.8 | |
| Myelencephalon | 3.21 ± 0.77 | |
| Occipital Lobe | 2.71 ± 0.69 | |
| Parietal Lobe | 3.02 ± 0.75 | |
| Pontine Tegmentum | 3.18 ± 0.65 | |
| Striatum | 2.1 ± 0.74 | |
| Subthalamus | 3.1 ± 0.73 | |
| Temporal Lobe | 3.17 ± 0.68 | |
| Thalamus | 3.18 ± 0.65 | |
| White Matter | 4.73 ± 0.39 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ptpla | CB | Cerebellum | 15.16 | |
| 19.13 | | |||
| Ptpla | CTX | Cerebral cortex | 12.5 | |
| 8.77 | | |||
| Ptpla | HIP | Hippocampal region | 7.23 | |
| 6.63 | | |||
| Ptpla | HPF | Hippocampal formation | 8.66 | |
| 7.49 | | |||
| Ptpla | HY | Hypothalamus | 3.77 | |
| 2.83 | | |||
| Ptpla | LSX | Lateral septal complex | 3.3 | |
| 2 | | |||
| Ptpla | MB | Midbrain | 3.35 | |
| 3.3 | | |||
| Ptpla | MY | Medulla | 6.15 | |
| 7.47 | | |||
| Ptpla | OLF | Olfactory bulb | 12.06 | |
| 9.5 | | |||
| Ptpla | P | Pons | 4.28 | |
| 5.04 | | |||
| Ptpla | PAL | Pallidum | 1.5 | |
| 1.52 | | |||
| Ptpla | RHP | Retrohippocampal region | 11.43 | |
| 9.08 | | |||
| Ptpla | sAMY | Striatum-like amygdalar nuclei | 2.17 | |
| 2.01 | | |||
| Ptpla | STR | Striatum | 1.7 | |
| 1.41 | | |||
| Ptpla | STRd | Striatum dorsal region | 1.16 | |
| 0.9 | | |||
| Ptpla | STRv | Striatum ventral region | 2.68 | |
| 1.97 | | |||
| Ptpla | TH | Thalamus | 3.26 | |
| 2.6 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00043087 | 10 | 277 | 286 | VLHGEVIVEK | Peptide Atlas |