AutismKB 2.0

Annotation Detail for BMP15


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Basic Information Top
Gene Symbol:BMP15 ( GDF9B,ODG2,POF4 )
Gene Full Name: bone morphogenetic protein 15
Band: Xp11.22
Quick LinksEntrez ID:9210; OMIM: 300247; Uniprot ID:BMP15_HUMAN; ENSEMBL ID: ENSG00000130385; HGNC ID: 1068
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221332_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.75
Adipocyte4.85
AdrenalCortex5.05
Adrenalgland4.35
Amygdala5.2
Appendix6
AtrioventricularNode3.9
BDCA4+_DentriticCells5.1
Bonemarrow5.15
BronchialEpithelialCells4.75
CD105+_Endothelial4.85
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid6.1
CD34+6.15
CD4+_Tcells5.2
CD56+_NKCells5.55
CD71+_EarlyErythroid4.55
CD8+_Tcells4.5
CardiacMyocytes6.15
Caudatenucleus4.4
Cerebellum4.05
CerebellumPeduncles5.7
CiliaryGanglion4.2
CingulateCortex5
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.75
FetalThyroid4.8
Fetalbrain4.95
Fetalliver4.25
Fetallung4.15
GlobusPallidus3.55
Heart6.45
Hypothalamus5.25
Kidney4.25
Leukemia_chronicMyelogenousK-5624.45
Leukemia_promyelocytic-HL-604.35
Leukemialymphoblastic(MOLT-4)4
Liver6.5
Lung5.4
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.55
OccipitalLobe4.4
OlfactoryBulb3.9
Ovary3.45
Pancreas4
PancreaticIslet5.25
ParietalLobe5.2
Pituitary5.75
Placenta5.05
Pons4.7
PrefrontalCortex6.15
Prostate5.8
Salivarygland4
SkeletalMuscle7.3
Skin3.9
SmoothMuscle5.6
Spinalcord5.3
SubthalamicNucleus4.45
SuperiorCervicalGanglion6.65
TemporalLobe4.6
Testis4.3
TestisGermCell4.15
TestisIntersitial4.55
TestisLeydigCell4.95
TestisSeminiferousTubule4.25
Thalamus5
Thymus3.95
Thyroid6.15
Tongue4.95
Tonsil5.3
Trachea4.15
TrigeminalGanglion5.15
Uterus4
UterusCorpus4.65
WholeBlood5.35
Wholebrain4.15
colon4.95
pineal_day6
pineal_night5.88
retina5.95
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13474_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.99 ± 1
Basal Forebrain1.53 ± 0.2
Basal Part of Pons1.23 ± 0.3
Cerebellar Cortex1.35 ± 0.68
Cerebellar Nuclei1.82 ± 0.72
Claustrum2.41 ± 0.87
Epithalamus1.27 ± 0.74
Frontal Lobe1.37 ± 0.59
Globus Pallidus2.17 ± 0.33
Hypothalamus1.62 ± 0.68
Insula1.44 ± 0.49
Limbic Lobe1.55 ± 0.59
Mesencephalon1.65 ± 0.6
Myelencephalon1.58 ± 0.67
Occipital Lobe1.57 ± 0.58
Parietal Lobe1.57 ± 0.77
Pontine Tegmentum1.6 ± 0.76
Striatum1.74 ± 0.6
Subthalamus1.72 ± 0.6
Temporal Lobe1.41 ± 0.53
Thalamus1.51 ± 0.57
White Matter2.13 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bmp15CBCerebellum0.36
0.84
Bmp15CTXCerebral cortex5.74
4.27
Bmp15HIPHippocampal region8.99
8.81
Bmp15HPFHippocampal formation7.93
7.42
Bmp15HYHypothalamus2.04
3.1
Bmp15LSXLateral septal complex0.26
1.52
Bmp15MBMidbrain1.39
2.61
Bmp15MYMedulla0.49
1.15
Bmp15OLFOlfactory bulb10.53
7.53
Bmp15PPons1.64
5.3
Bmp15PALPallidum1.37
1.25
Bmp15RHPRetrohippocampal region5.84
5.14
Bmp15sAMYStriatum-like amygdalar nuclei6.7
4.38
Bmp15STRStriatum2.81
2.19
Bmp15STRdStriatum dorsal region2.84
2.19
Bmp15STRvStriatum ventral region1.43
1.44
Bmp15THThalamus4.84
3.5
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
BMP15_HUMAN_2 7 2 8 VLLSILR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018