AutismKB 2.0

Annotation Detail for NOLC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NOLC1 ( KIAA0035,NOPP130,NOPP140,NS5ATP13,P130 )
Gene Full Name: nucleolar and coiled-body phosphoprotein 1
Band: 10q24.32
Quick LinksEntrez ID:9221; OMIM: 602394; Uniprot ID:NOLC1_HUMAN; ENSEMBL ID: ENSG00000166197; HGNC ID: 15608
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst21 / 62319336
fetus58 / 564012102
neonate1 / 3109732
infant12 / 23620508
juvenile12 / 55556215
adult259 / 1939121133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor38 / 94178403
cervical tumor16 / 34366465
chondrosarcoma13 / 82823156
colorectal tumor19 / 114246166
esophageal tumor4 / 17290231
gastrointestinal tumor23 / 119369192
germ cell tumor65 / 263845246
glioma13 / 106883121
head and neck tumor18 / 136302132
kidney tumor3 / 6895943
leukemia13 / 95842135
liver tumor15 / 96359155
lung tumor9 / 10312787
lymphoma6 / 7175583
non-neoplasia7 / 9725071
normal348 / 3360307103
ovarian tumor7 / 7668291
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS28 / 125680222
prostate cancer15 / 102680146
retinoblastoma17 / 46356366
skin tumor21 / 124949168
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites10 / 40015249
bladder2 / 2975767
blood13 / 123478105
bone15 / 71655209
bone marrow6 / 48801122
brain105 / 110098995
cervix16 / 48171332
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue47 / 215722217
esophagus4 / 20209197
eye26 / 211054123
heart16 / 89626178
intestine40 / 234472170
kidney26 / 211777122
larynx2 / 2414582
liver23 / 207743110
lung45 / 336974133
lymph4 / 4427090
lymph node15 / 91610163
mammary gland41 / 153271267
mouth10 / 67052149
muscle6 / 10771555
nerve2 / 15768126
ovary11 / 102051107
pancreas14 / 21481265
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta33 / 280825117
prostate26 / 189345137
salivary gland0 / 201550 
skin39 / 210574185
spleen4 / 5395274
stomach28 / 96619289
testis34 / 330442102
thymus4 / 8113149
thyroid12 / 47473252
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus31 / 232878133
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211949_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.6
Adipocyte4.3
AdrenalCortex4.55
Adrenalgland3.65
Amygdala4.4
Appendix4.35
AtrioventricularNode3.5
BDCA4+_DentriticCells7.1
Bonemarrow4.25
BronchialEpithelialCells4.6
CD105+_Endothelial5.05
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)5.75
CD33+_Myeloid6.1
CD34+8.35
CD4+_Tcells5.95
CD56+_NKCells5.4
CD71+_EarlyErythroid4
CD8+_Tcells4.3
CardiacMyocytes5.5
Caudatenucleus3.85
Cerebellum3.55
CerebellumPeduncles4.95
CiliaryGanglion3
CingulateCortex4.45
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.35
FetalThyroid4.2
Fetalbrain4.4
Fetalliver3.8
Fetallung3.65
GlobusPallidus3.15
Heart5.65
Hypothalamus4.6
Kidney3.6
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.9
Liver5.7
Lung4.65
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.9
Lymphoma_burkitts(Raji)6
MedullaOblongata4
OccipitalLobe3.9
OlfactoryBulb3.45
Ovary2.9
Pancreas3.5
PancreaticIslet4.65
ParietalLobe4.55
Pituitary5.1
Placenta4.7
Pons4.15
PrefrontalCortex5.45
Prostate4.95
Salivarygland3.55
SkeletalMuscle5.05
Skin3.65
SmoothMuscle5.35
Spinalcord4.55
SubthalamicNucleus4
SuperiorCervicalGanglion5
TemporalLobe4
Testis3.75
TestisGermCell3.7
TestisIntersitial3.7
TestisLeydigCell4.25
TestisSeminiferousTubule3.75
Thalamus4.4
Thymus3.45
Thyroid5.3
Tongue4.2
Tonsil5.7
Trachea3.65
TrigeminalGanglion4.35
Uterus3.45
UterusCorpus3.85
WholeBlood4.6
Wholebrain3.65
colon4.3
pineal_day5.38
pineal_night5.22
retina5.425
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P202143
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.34 ± 0.17
Basal Forebrain9.1 ± 0.15
Basal Part of Pons9.25 ± 0.16
Cerebellar Cortex9.33 ± 0.14
Cerebellar Nuclei9.09 ± 0.17
Claustrum9.43 ± 0.26
Epithalamus9.08 ± 0.18
Frontal Lobe9.26 ± 0.21
Globus Pallidus8.85 ± 0.13
Hypothalamus9.35 ± 0.23
Insula9.31 ± 0.27
Limbic Lobe9.29 ± 0.27
Mesencephalon9.26 ± 0.26
Myelencephalon9.17 ± 0.22
Occipital Lobe9.22 ± 0.23
Parietal Lobe9.27 ± 0.21
Pontine Tegmentum9.24 ± 0.25
Striatum8.9 ± 0.18
Subthalamus9.16 ± 0.19
Temporal Lobe9.27 ± 0.2
Thalamus9.06 ± 0.22
White Matter9 ± 0.13
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064164 23 37 59 ATGATQQDANASSLLDIYSFWLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved