AutismKB 2.0

Annotation Detail for MAGI1


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Basic Information Top
Gene Symbol:MAGI1 ( AIP3,BAIAP1,BAP1,MAGI-1,TNRC19,WWP3 )
Gene Full Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Band: 3p14.1
Quick LinksEntrez ID:9223; OMIM: 602625; Uniprot ID:MAGI1_HUMAN; ENSEMBL ID: ENSG00000151276; HGNC ID: 946
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst5 / 6231980
fetus42 / 56401274
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor15 / 26384556
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal171 / 336030750
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder4 / 29757134
blood0 / 1234780 
bone2 / 7165527
bone marrow2 / 4880140
brain56 / 110098950
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye19 / 21105490
heart8 / 8962689
intestine4 / 23447217
kidney12 / 21177756
larynx0 / 241450 
liver5 / 20774324
lung14 / 33697441
lymph0 / 442700 
lymph node3 / 9161032
mammary gland7 / 15327145
mouth0 / 670520 
muscle4 / 10771537
nerve2 / 15768126
ovary5 / 10205148
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach10 / 96619103
testis9 / 33044227
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206144_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte5.8
AdrenalCortex7.2
Adrenalgland5.25
Amygdala6.75
Appendix13.9
AtrioventricularNode6.7
BDCA4+_DentriticCells6
Bonemarrow6.25
BronchialEpithelialCells5.65
CD105+_Endothelial5.95
CD14+_Monocytes6.3
CD19+_BCells(neg._sel.)6.05
CD33+_Myeloid7.2
CD34+7.1
CD4+_Tcells6
CD56+_NKCells6.8
CD71+_EarlyErythroid5.75
CD8+_Tcells5.3
CardiacMyocytes8.35
Caudatenucleus5.75
Cerebellum5
CerebellumPeduncles7.65
CiliaryGanglion6.75
CingulateCortex9
Colorectaladenocarcinoma6
DorsalRootGanglion5.9
FetalThyroid6.8
Fetalbrain6.25
Fetalliver5.55
Fetallung4.65
GlobusPallidus14
Heart8.85
Hypothalamus8.65
Kidney5.2
Leukemia_chronicMyelogenousK-5625.35
Leukemia_promyelocytic-HL-605.2
Leukemialymphoblastic(MOLT-4)4.5
Liver9.9
Lung6.6
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)9.05
MedullaOblongata17.65
OccipitalLobe10.6
OlfactoryBulb4.7
Ovary4.4
Pancreas5
PancreaticIslet6.5
ParietalLobe7.3
Pituitary7.15
Placenta6
Pons7.45
PrefrontalCortex8.3
Prostate6.95
Salivarygland4.95
SkeletalMuscle8.4
Skin6.4
SmoothMuscle6.85
Spinalcord6.55
SubthalamicNucleus6.25
SuperiorCervicalGanglion9.45
TemporalLobe5.9
Testis5.3
TestisGermCell5
TestisIntersitial5.25
TestisLeydigCell6.2
TestisSeminiferousTubule5.25
Thalamus6.95
Thymus4.45
Thyroid7.35
Tongue7.65
Tonsil6
Trachea5
TrigeminalGanglion9.2
Uterus4.9
UterusCorpus5.75
WholeBlood6.4
Wholebrain10.2
colon6.15
pineal_day16.5
pineal_night14.58
retina7.55
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9004_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.23 ± 0.48
Basal Forebrain5.19 ± 0.46
Basal Part of Pons4.56 ± 0.56
Cerebellar Cortex5.39 ± 0.26
Cerebellar Nuclei4.9 ± 0.56
Claustrum6.1 ± 0.31
Epithalamus4.59 ± 0.74
Frontal Lobe5.25 ± 0.49
Globus Pallidus4.46 ± 0.38
Hypothalamus4.84 ± 0.64
Insula5.48 ± 0.38
Limbic Lobe5.03 ± 0.5
Mesencephalon5.34 ± 0.61
Myelencephalon5.12 ± 0.57
Occipital Lobe4.82 ± 0.7
Parietal Lobe5.21 ± 0.41
Pontine Tegmentum5.2 ± 0.5
Striatum4.23 ± 0.58
Subthalamus4.44 ± 0.49
Temporal Lobe5.39 ± 0.37
Thalamus5.24 ± 0.56
White Matter4.66 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Magi1CBCerebellum81.46
100
Magi1CTXCerebral cortex100
100
Magi1HIPHippocampal region49.29
76.86
Magi1HPFHippocampal formation64.01
92.72
Magi1HYHypothalamus31.79
32.04
Magi1LSXLateral septal complex85.39
83.91
Magi1MBMidbrain56.14
68.93
Magi1MYMedulla100
100
Magi1OLFOlfactory bulb100
100
Magi1PPons57.63
77.3
Magi1PALPallidum51.84
58.06
Magi1RHPRetrohippocampal region83
100
Magi1sAMYStriatum-like amygdalar nuclei24.25
25.06
Magi1STRStriatum43.13
42.27
Magi1STRdStriatum dorsal region37.8
35.92
Magi1STRvStriatum ventral region54.45
54.56
Magi1THThalamus28.12
28.44
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MAGI1_HUMAN_1341 9 1341 1349 AAAANGPKR PRIDE
PAp00061193 8 924 931 KVVFAVPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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