AutismKB 2.0

Annotation Detail for DLGAP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DLGAP1 ( DAP-1,DAP-1-ALPHA,DAP-1-BETA,GKAP,MGC88156,SAPAP1,hGKAP )
Gene Full Name: discs, large (Drosophila) homolog-associated protein 1
Band: 18p11.31
Quick LinksEntrez ID:9229; OMIM: 605445; Uniprot ID:DLGP1_HUMAN; ENSEMBL ID: ENSG00000170579; HGNC ID: 2905
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal78 / 336030723
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain68 / 110098961
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210750_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.4
Adipocyte8.6
AdrenalCortex11.85
Adrenalgland9.8
Amygdala11.8
Appendix11.6
AtrioventricularNode7.15
BDCA4+_DentriticCells7.65
Bonemarrow9.4
BronchialEpithelialCells8.7
CD105+_Endothelial8
CD14+_Monocytes8.85
CD19+_BCells(neg._sel.)8.25
CD33+_Myeloid9.4
CD34+9.6
CD4+_Tcells7.65
CD56+_NKCells8.45
CD71+_EarlyErythroid8.3
CD8+_Tcells6.55
CardiacMyocytes12.5
Caudatenucleus10.2
Cerebellum15
CerebellumPeduncles11
CiliaryGanglion6.55
CingulateCortex9.7
Colorectaladenocarcinoma9.15
DorsalRootGanglion6.8
FetalThyroid8.9
Fetalbrain8.85
Fetalliver8.7
Fetallung7.35
GlobusPallidus6.65
Heart15.75
Hypothalamus9.85
Kidney9.45
Leukemia_chronicMyelogenousK-5628.25
Leukemia_promyelocytic-HL-608.05
Leukemialymphoblastic(MOLT-4)6.7
Liver16.95
Lung10
Lymphnode7.95
Lymphoma_burkitts(Daudi)11.9
Lymphoma_burkitts(Raji)14.35
MedullaOblongata8.35
OccipitalLobe8.15
OlfactoryBulb6.9
Ovary6.65
Pancreas7.4
PancreaticIslet9.8
ParietalLobe10.2
Pituitary10.7
Placenta9.6
Pons9.65
PrefrontalCortex10.55
Prostate10.6
Salivarygland7.8
SkeletalMuscle11.85
Skin6.8
SmoothMuscle10.25
Spinalcord10.2
SubthalamicNucleus8.25
SuperiorCervicalGanglion13.4
TemporalLobe8.7
Testis8.15
TestisGermCell7
TestisIntersitial7.65
TestisLeydigCell9.2
TestisSeminiferousTubule7.8
Thalamus9.2
Thymus7.35
Thyroid11.3
Tongue10.8
Tonsil8.9
Trachea8.85
TrigeminalGanglion9.75
Uterus7.3
UterusCorpus13.1
WholeBlood11
Wholebrain11.3
colon9.55
pineal_day9.76
pineal_night9.9
retina12.45
small_intestine8.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_236_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.53 ± 0.74
Basal Forebrain8.43 ± 0.4
Basal Part of Pons9.39 ± 0.26
Cerebellar Cortex8.93 ± 0.32
Cerebellar Nuclei7.6 ± 0.66
Claustrum9.53 ± 0.55
Epithalamus7.33 ± 0.68
Frontal Lobe8.55 ± 0.61
Globus Pallidus6.22 ± 0.68
Hypothalamus7.35 ± 0.59
Insula8.6 ± 0.49
Limbic Lobe9.37 ± 0.63
Mesencephalon8.15 ± 0.54
Myelencephalon8.51 ± 0.69
Occipital Lobe9.73 ± 0.78
Parietal Lobe9 ± 0.57
Pontine Tegmentum8.46 ± 0.72
Striatum7.73 ± 0.76
Subthalamus8.95 ± 0.15
Temporal Lobe8.76 ± 0.48
Thalamus8.41 ± 0.6
White Matter6.14 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dlgap1CBCerebellum88.24
100
Dlgap1CTXCerebral cortex100
100
Dlgap1HIPHippocampal region100
100
Dlgap1HPFHippocampal formation100
100
Dlgap1HYHypothalamus25.19
21.55
Dlgap1LSXLateral septal complex100
100
Dlgap1MBMidbrain25.26
24.3
Dlgap1MYMedulla29.17
37.01
Dlgap1OLFOlfactory bulb100
100
Dlgap1PPons26.57
32.7
Dlgap1PALPallidum47.19
47.66
Dlgap1RHPRetrohippocampal region100
100
Dlgap1sAMYStriatum-like amygdalar nuclei97.48
95.85
Dlgap1STRStriatum55.04
54.45
Dlgap1STRdStriatum dorsal region34.77
34.71
Dlgap1STRvStriatum ventral region56.78
48.6
Dlgap1THThalamus81.26
88.83
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved