AutismKB 2.0

Annotation Detail for MEX3A


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Basic Information Top
Gene Symbol:MEX3A ( MEX-3A,RKHD4 )
Gene Full Name: mex-3 homolog A (C. elegans)
Band: 1q22
Quick LinksEntrez ID:92312; OMIM: 611007; Uniprot ID:MEX3A_HUMAN; ENSEMBL ID: ; HGNC ID: 33482
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus49 / 56401286
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor15 / 26384556
glioma9 / 10688384
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal95 / 336030728
ovarian tumor6 / 7668278
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma11 / 46356237
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain39 / 110098935
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye25 / 211054118
heart3 / 8962633
intestine6 / 23447225
kidney2 / 2117779
larynx0 / 241450 
liver4 / 20774319
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary6 / 10205158
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P857404
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.49 ± 0.34
Basal Forebrain4.81 ± 0.24
Basal Part of Pons4.39 ± 0.4
Cerebellar Cortex4.79 ± 0.35
Cerebellar Nuclei4.7 ± 0.33
Claustrum4.04 ± 0.63
Epithalamus4.99 ± 0.39
Frontal Lobe4.44 ± 0.46
Globus Pallidus4.92 ± 0.36
Hypothalamus4.29 ± 0.57
Insula4.43 ± 0.39
Limbic Lobe4.54 ± 0.52
Mesencephalon4.43 ± 0.47
Myelencephalon4.54 ± 0.5
Occipital Lobe4.46 ± 0.44
Parietal Lobe4.34 ± 0.51
Pontine Tegmentum4.45 ± 0.48
Striatum4.72 ± 0.48
Subthalamus3.91 ± 0.47
Temporal Lobe4.4 ± 0.47
Thalamus4.7 ± 0.44
White Matter5.25 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2700083E18RikCBCerebellum9.34
12
2700083E18RikCTXCerebral cortex5.67
4.18
2700083E18RikHIPHippocampal region5.18
5.14
2700083E18RikHPFHippocampal formation5.26
4.78
2700083E18RikHYHypothalamus1.13
1
2700083E18RikLSXLateral septal complex1.27
1.17
2700083E18RikMBMidbrain1.91
2.76
2700083E18RikMYMedulla4.14
4.32
2700083E18RikOLFOlfactory bulb7.77
5.63
2700083E18RikPPons2.77
4.2
2700083E18RikPALPallidum0.14
0.13
2700083E18RikRHPRetrohippocampal region5.65
4.47
2700083E18RiksAMYStriatum-like amygdalar nuclei0.6
0.68
2700083E18RikSTRStriatum2.29
1.9
2700083E18RikSTRdStriatum dorsal region2.69
2.22
2700083E18RikSTRvStriatum ventral region1.64
1.03
2700083E18RikTHThalamus0.85
1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018