AutismKB 2.0

Annotation Detail for DHRS3


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Basic Information Top
Gene Symbol:DHRS3 ( RDH17,Rsdr1,SDR1,SDR16C1,retSDR1 )
Gene Full Name: dehydrogenase/reductase (SDR family) member 3
Band: 1p36.21
Quick LinksEntrez ID:9249; OMIM: 612830; Uniprot ID:DHRS3_HUMAN; ENSEMBL ID: ENSG00000162496; HGNC ID: 17693
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult131 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor6 / 34366174
chondrosarcoma6 / 8282372
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor7 / 26384526
glioma5 / 10688346
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor8 / 9635983
lung tumor11 / 103127106
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal139 / 336030741
ovarian tumor14 / 76682182
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue8 / 13106610
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood1 / 1234788
bone4 / 7165555
bone marrow2 / 4880140
brain25 / 110098922
cervix9 / 48171186
connective tissue10 / 14925566
ear1 / 1621261
embryonic tissue4 / 21572218
esophagus2 / 2020998
eye11 / 21105452
heart2 / 8962622
intestine20 / 23447285
kidney18 / 21177784
larynx2 / 2414582
liver18 / 20774386
lung33 / 33697497
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary14 / 102051137
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta6 / 28082521
prostate21 / 189345110
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach5 / 9661951
testis5 / 33044215
thymus2 / 8113124
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202481_at
Cell line Expression level Expression bar
721_B_lymphoblasts23
Adipocyte358.35
AdrenalCortex56.3
Adrenalgland99.25
Amygdala28.55
Appendix162.5
AtrioventricularNode79.45
BDCA4+_DentriticCells23.85
Bonemarrow82.4
BronchialEpithelialCells76.65
CD105+_Endothelial78.4
CD14+_Monocytes14.75
CD19+_BCells(neg._sel.)39.4
CD33+_Myeloid25.9
CD34+48.65
CD4+_Tcells77.05
CD56+_NKCells375.15
CD71+_EarlyErythroid81.85
CD8+_Tcells91.4
CardiacMyocytes890.6
Caudatenucleus41.5
Cerebellum43.55
CerebellumPeduncles66.8
CiliaryGanglion93.9
CingulateCortex64.75
Colorectaladenocarcinoma64.2
DorsalRootGanglion101.6
FetalThyroid272.9
Fetalbrain30.85
Fetalliver129.5
Fetallung240.45
GlobusPallidus34.45
Heart639.45
Hypothalamus48.55
Kidney245.05
Leukemia_chronicMyelogenousK-562254.05
Leukemia_promyelocytic-HL-6040.25
Leukemialymphoblastic(MOLT-4)42.85
Liver2383.95
Lung503.9
Lymphnode113
Lymphoma_burkitts(Daudi)64.95
Lymphoma_burkitts(Raji)36.6
MedullaOblongata55.8
OccipitalLobe29.6
OlfactoryBulb738.75
Ovary34
Pancreas138.95
PancreaticIslet267.1
ParietalLobe62.7
Pituitary281.85
Placenta196.6
Pons64.75
PrefrontalCortex72.9
Prostate682.75
Salivarygland86.15
SkeletalMuscle73
Skin56.5
SmoothMuscle1689.9
Spinalcord182
SubthalamicNucleus63.9
SuperiorCervicalGanglion129.85
TemporalLobe85.2
Testis48.4
TestisGermCell24.45
TestisIntersitial37.25
TestisLeydigCell46.25
TestisSeminiferousTubule38.25
Thalamus60.4
Thymus92.05
Thyroid175.6
Tongue100.05
Tonsil44.65
Trachea188.4
TrigeminalGanglion59.4
Uterus78.2
UterusCorpus198.65
WholeBlood40.45
Wholebrain83.05
colon51.5
pineal_day81.6
pineal_night49.82
retina241.725
small_intestine76.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P33759
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.36 ± 0.23
Basal Forebrain8.1 ± 0.41
Basal Part of Pons7.19 ± 0.42
Cerebellar Cortex7.47 ± 0.25
Cerebellar Nuclei7.52 ± 0.18
Claustrum8.49 ± 0.33
Epithalamus9.02 ± 0.7
Frontal Lobe8.01 ± 0.51
Globus Pallidus9.15 ± 0.35
Hypothalamus8.37 ± 0.26
Insula7.78 ± 0.33
Limbic Lobe8.03 ± 0.67
Mesencephalon8.2 ± 0.66
Myelencephalon8.18 ± 0.5
Occipital Lobe8.27 ± 0.35
Parietal Lobe8.11 ± 0.43
Pontine Tegmentum8.06 ± 0.41
Striatum8.99 ± 0.37
Subthalamus7.65 ± 0.59
Temporal Lobe7.88 ± 0.38
Thalamus8.16 ± 0.39
White Matter7.48 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dhrs3CBCerebellum36.83
42.79
Dhrs3CTXCerebral cortex45.45
27.06
Dhrs3HIPHippocampal region32.59
24.2
Dhrs3HPFHippocampal formation44.94
32.96
Dhrs3HYHypothalamus25.55
14.06
Dhrs3LSXLateral septal complex19.72
9.47
Dhrs3MBMidbrain39.68
25
Dhrs3MYMedulla41.54
34.41
Dhrs3OLFOlfactory bulb49.23
27.08
Dhrs3PPons51.94
40.22
Dhrs3PALPallidum23.36
14.62
Dhrs3RHPRetrohippocampal region50.33
44.31
Dhrs3sAMYStriatum-like amygdalar nuclei33.81
17.41
Dhrs3STRStriatum19.76
10.4
Dhrs3STRdStriatum dorsal region17.34
9.11
Dhrs3STRvStriatum ventral region19.28
10.49
Dhrs3THThalamus33.3
19.62
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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