Annotation Detail for CD8A
Basic Information Top
| Gene Symbol: | CD8A ( CD8,Leu2,MAL,p32 ) |
|---|---|
| Gene Full Name: | CD8a molecule |
| Band: | 2p11.2 |
| Quick Links | Entrez ID:925; OMIM: 186910; Uniprot ID:CD8A_HUMAN; ENSEMBL ID: ENSG00000153563; HGNC ID: 1706 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.85258
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 36 / 1939121 | 18 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 1 / 17290 | 57 |  |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 8 / 96359 | 83 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 171 / 3360307 | 50 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 14 / 123478 | 113 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 17 / 1100989 | 15 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 0 / 211054 | 0 | |
| heart | 2 / 89626 | 22 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 8 / 207743 | 38 | |
| lung | 10 / 336974 | 29 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 91 / 53952 | 1686 |  |
| stomach | 6 / 96619 | 62 | |
| testis | 2 / 330442 | 6 | |
| thymus | 351 / 81131 | 4326 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205758_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 8.25 | |
| Adipocyte | 7.9 | |
| AdrenalCortex | 9.1 | |
| Adrenalgland | 10.5 | |
| Amygdala | 8.25 | |
| Appendix | 12.85 | |
| AtrioventricularNode | 7.8 | |
| BDCA4+_DentriticCells | 7.2 | |
| Bonemarrow | 34.55 | |
| BronchialEpithelialCells | 7.45 | |
| CD105+_Endothelial | 7.4 | |
| CD14+_Monocytes | 8.25 | |
| CD19+_BCells(neg._sel.) | 7.95 | |
| CD33+_Myeloid | 9.55 | |
| CD34+ | 9.6 | |
| CD4+_Tcells | 688.45 |  |
| CD56+_NKCells | 119.95 | |
| CD71+_EarlyErythroid | 7.6 | |
| CD8+_Tcells | 1307.4 | |
| CardiacMyocytes | 10.25 | |
| Caudatenucleus | 7.3 | |
| Cerebellum | 7.4 | |
| CerebellumPeduncles | 9.4 | |
| CiliaryGanglion | 5.8 | |
| CingulateCortex | 10.15 | |
| Colorectaladenocarcinoma | 8 | |
| DorsalRootGanglion | 7.45 | |
| FetalThyroid | 7.75 | |
| Fetalbrain | 8.05 | |
| Fetalliver | 7 | |
| Fetallung | 6.65 | |
| GlobusPallidus | 6.8 | |
| Heart | 23.85 | |
| Hypothalamus | 8.7 | |
| Kidney | 7.15 | |
| Leukemia_chronicMyelogenousK-562 | 7.2 | |
| Leukemia_promyelocytic-HL-60 | 6.9 | |
| Leukemialymphoblastic(MOLT-4) | 8.75 | |
| Liver | 10.9 | |
| Lung | 16.9 | |
| Lymphnode | 16.9 | |
| Lymphoma_burkitts(Daudi) | 10.25 | |
| Lymphoma_burkitts(Raji) | 11.2 | |
| MedullaOblongata | 7.35 | |
| OccipitalLobe | 7.15 | |
| OlfactoryBulb | 6.35 | |
| Ovary | 5.45 | |
| Pancreas | 6.45 | |
| PancreaticIslet | 8.55 | |
| ParietalLobe | 10.25 | |
| Pituitary | 11.1 | |
| Placenta | 8.3 | |
| Pons | 8 | |
| PrefrontalCortex | 9.95 | |
| Prostate | 14.8 | |
| Salivarygland | 8 | |
| SkeletalMuscle | 10.6 | |
| Skin | 7.1 | |
| SmoothMuscle | 8.75 | |
| Spinalcord | 8.65 | |
| SubthalamicNucleus | 7.55 | |
| SuperiorCervicalGanglion | 12.2 | |
| TemporalLobe | 8.25 | |
| Testis | 6.9 | |
| TestisGermCell | 7.25 | |
| TestisIntersitial | 7.05 | |
| TestisLeydigCell | 8.2 | |
| TestisSeminiferousTubule | 7.75 | |
| Thalamus | 8.15 | |
| Thymus | 1532.9 | |
| Thyroid | 10.15 | |
| Tongue | 8.45 | |
| Tonsil | 9 | |
| Trachea | 9.45 | |
| TrigeminalGanglion | 8.3 | |
| Uterus | 6.35 | |
| UterusCorpus | 8.1 | |
| WholeBlood | 289.05 | |
| Wholebrain | 6.75 | |
| colon | 8.05 | |
| pineal_day | 9.44 | |
| pineal_night | 10.1 | |
| retina | 9.725 | |
| small_intestine | 9.25 | |
- Probe name: CUST_12384_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.15 ± 1 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.56 ± 0.24 | |
| Basal Part of Pons | 1.37 ± 0.66 | |
| Cerebellar Cortex | 1.65 ± 0.85 | |
| Cerebellar Nuclei | 2.09 ± 1 | |
| Claustrum | 2.78 ± 1.01 | |
| Epithalamus | 1.54 ± 0.95 | |
| Frontal Lobe | 1.52 ± 0.62 | |
| Globus Pallidus | 2.34 ± 0.43 | |
| Hypothalamus | 1.76 ± 0.7 | |
| Insula | 1.43 ± 0.53 | |
| Limbic Lobe | 1.75 ± 0.73 | |
| Mesencephalon | 2 ± 0.81 | |
| Myelencephalon | 1.79 ± 0.7 | |
| Occipital Lobe | 1.87 ± 0.81 | |
| Parietal Lobe | 1.87 ± 0.9 | |
| Pontine Tegmentum | 1.8 ± 0.68 | |
| Striatum | 1.91 ± 0.54 | |
| Subthalamus | 1.83 ± 0.64 | |
| Temporal Lobe | 1.67 ± 0.73 | |
| Thalamus | 1.67 ± 0.57 | |
| White Matter | 1.99 ± 0.22 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cd8a | CB | Cerebellum | 12.51 | |
| 12.55 | | |||
| Cd8a | CTX | Cerebral cortex | 33.72 | |
| 23.34 | | |||
| Cd8a | HIP | Hippocampal region | 33.14 | |
| 46.69 | | |||
| Cd8a | HPF | Hippocampal formation | 32.65 | |
| 37.03 | | |||
| Cd8a | HY | Hypothalamus | 1.89 | |
| 1.27 | | |||
| Cd8a | LSX | Lateral septal complex | 4.94 | |
| 4.48 | | |||
| Cd8a | MB | Midbrain | 3.07 | |
| 2.68 | | |||
| Cd8a | MY | Medulla | 8.65 | |
| 7.78 | | |||
| Cd8a | OLF | Olfactory bulb | 24.77 | |
| 19.55 | | |||
| Cd8a | P | Pons | 5.61 | |
| 5 | | |||
| Cd8a | PAL | Pallidum | 3.89 | |
| 3.08 | | |||
| Cd8a | RHP | Retrohippocampal region | 31.94 | |
| 24.64 | | |||
| Cd8a | sAMY | Striatum-like amygdalar nuclei | 10.51 | |
| 7.14 | | |||
| Cd8a | STR | Striatum | 6.89 | |
| 4.89 | | |||
| Cd8a | STRd | Striatum dorsal region | 7.38 | |
| 5.16 | | |||
| Cd8a | STRv | Striatum ventral region | 4.71 | |
| 3.43 | | |||
| Cd8a | TH | Thalamus | 4.61 | |
| 3.79 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00009647 | 19 | 43 | 61 | CQVLLSNPTSGCSWLFQPR | Peptide Atlas |