Annotation Detail for NUMBL
Basic Information Top
| Gene Symbol: | NUMBL ( CAG3A,CTG3a,NBL,NUMB-R,NUMBLIKE,NUMBR,TNRC23 ) |
|---|---|
| Gene Full Name: | numb homolog (Drosophila)-like |
| Band: | 19q13.2 |
| Quick Links | Entrez ID:9253; OMIM: 604018; Uniprot ID:NUMBL_HUMAN; ENSEMBL ID: ENSG00000105245; HGNC ID: 8061 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.326953
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 22 / 564012 | 39 | |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 21 / 1939121 | 10 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 6 / 106883 | 56 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 69 / 3360307 | 20 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 22 / 104616 | 210 |  |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 3 / 29757 | 100 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 54 / 1100989 | 49 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 5 / 211054 | 23 | |
| heart | 1 / 89626 | 11 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 7 / 336974 | 20 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 29 / 214812 | 135 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 2 / 96619 | 20 | |
| testis | 3 / 330442 | 9 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 2 / 51780 | 38 | |
Microarray in - Probe name: CUST_8866_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.04 ± 0.9 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.27 ± 0.22 | |
| Basal Part of Pons | 2.2 ± 0.33 | |
| Cerebellar Cortex | 2.64 ± 0.77 | |
| Cerebellar Nuclei | 2.76 ± 0.75 | |
| Claustrum | 3.1 ± 0.64 | |
| Epithalamus | 2.17 ± 0.77 | |
| Frontal Lobe | 2.55 ± 0.7 | |
| Globus Pallidus | 2.51 ± 0.71 | |
| Hypothalamus | 2.6 ± 0.71 | |
| Insula | 2.59 ± 0.66 | |
| Limbic Lobe | 2.61 ± 0.57 | |
| Mesencephalon | 2.64 ± 0.66 | |
| Myelencephalon | 2.57 ± 0.68 | |
| Occipital Lobe | 2.05 ± 0.56 | |
| Parietal Lobe | 2.5 ± 0.68 | |
| Pontine Tegmentum | 2.64 ± 0.77 | |
| Striatum | 1.95 ± 0.54 | |
| Subthalamus | 2.72 ± 0.72 | |
| Temporal Lobe | 2.76 ± 0.72 | |
| Thalamus | 2.41 ± 0.65 | |
| White Matter | 2.22 ± 0.19 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Numbl | CB | Cerebellum | 48.2 | |
| 75.68 | | |||
| Numbl | CTX | Cerebral cortex | 100 | |
| 87.94 | | |||
| Numbl | HIP | Hippocampal region | 86.84 | |
| 100 | | |||
| Numbl | HPF | Hippocampal formation | 85.13 | |
| 100 | | |||
| Numbl | HY | Hypothalamus | 40.87 | |
| 34.61 | | |||
| Numbl | LSX | Lateral septal complex | 37.36 | |
| 28.41 | | |||
| Numbl | MB | Midbrain | 29.77 | |
| 27.28 | | |||
| Numbl | MY | Medulla | 35.63 | |
| 35.95 | | |||
| Numbl | OLF | Olfactory bulb | 72.47 | |
| 68.74 | | |||
| Numbl | P | Pons | 32.33 | |
| 30.89 | | |||
| Numbl | PAL | Pallidum | 47.29 | |
| 44.74 | | |||
| Numbl | RHP | Retrohippocampal region | 83.03 | |
| 76.21 | | |||
| Numbl | sAMY | Striatum-like amygdalar nuclei | 73.18 | |
| 57.63 | | |||
| Numbl | STR | Striatum | 61.67 | |
| 47.9 | | |||
| Numbl | STRd | Striatum dorsal region | 60.06 | |
| 46.04 | | |||
| Numbl | STRv | Striatum ventral region | 67.37 | |
| 53.45 | | |||
| Numbl | TH | Thalamus | 35.86 | |
| 32.59 | |