AutismKB 2.0

Annotation Detail for AIMP1


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Basic Information Top
Gene Symbol:AIMP1 ( EMAP2,EMAPII,SCYE1,p43 )
Gene Full Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Band: 4q24
Quick LinksEntrez ID:9255; OMIM: 603605; Uniprot ID:AIMP1_HUMAN; ENSEMBL ID: ENSG00000164022; HGNC ID: 10648
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus34 / 56401260
neonate2 / 3109764
infant1 / 2362042
juvenile1 / 5555617
adult120 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma11 / 82823132
colorectal tumor7 / 11424661
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor20 / 26384575
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia6 / 9725061
normal236 / 336030770
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor8 / 12494964
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites3 / 4001574
bladder1 / 2975733
blood9 / 12347872
bone10 / 71655139
bone marrow0 / 488010 
brain60 / 110098954
cervix1 / 4817120
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus3 / 20209148
eye15 / 21105471
heart8 / 8962689
intestine21 / 23447289
kidney23 / 211777108
larynx1 / 2414541
liver19 / 20774391
lung25 / 33697474
lymph1 / 4427022
lymph node9 / 9161098
mammary gland4 / 15327126
mouth1 / 6705214
muscle15 / 107715139
nerve0 / 157680 
ovary1 / 1020519
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta17 / 28082560
prostate12 / 18934563
salivary gland2 / 2015599
skin18 / 21057485
spleen2 / 5395237
stomach2 / 9661920
testis17 / 33044251
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord1 / 1368073
uterus16 / 23287868
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202541_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.2
Adipocyte10.05
AdrenalCortex12.9
Adrenalgland8.9
Amygdala10.95
Appendix13.85
AtrioventricularNode10.3
BDCA4+_DentriticCells51.4
Bonemarrow10.85
BronchialEpithelialCells14.9
CD105+_Endothelial17.9
CD14+_Monocytes26.7
CD19+_BCells(neg._sel.)59.5
CD33+_Myeloid27.2
CD34+29.05
CD4+_Tcells23.35
CD56+_NKCells44.6
CD71+_EarlyErythroid10.85
CD8+_Tcells22
CardiacMyocytes16.15
Caudatenucleus9.6
Cerebellum8.2
CerebellumPeduncles11.6
CiliaryGanglion8
CingulateCortex11.05
Colorectaladenocarcinoma10.55
DorsalRootGanglion8.35
FetalThyroid9.25
Fetalbrain10.65
Fetalliver9.3
Fetallung7.75
GlobusPallidus10.15
Heart16.3
Hypothalamus13.7
Kidney9.8
Leukemia_chronicMyelogenousK-56222.95
Leukemia_promyelocytic-HL-6034.5
Leukemialymphoblastic(MOLT-4)15.2
Liver16.05
Lung9
Lymphnode7.1
Lymphoma_burkitts(Daudi)20.3
Lymphoma_burkitts(Raji)19.3
MedullaOblongata8.7
OccipitalLobe11.05
OlfactoryBulb8
Ovary11.25
Pancreas8.7
PancreaticIslet18.6
ParietalLobe12
Pituitary19.55
Placenta8.8
Pons10.2
PrefrontalCortex14
Prostate11.55
Salivarygland8.8
SkeletalMuscle16.2
Skin10.6
SmoothMuscle12.7
Spinalcord12.85
SubthalamicNucleus9.9
SuperiorCervicalGanglion14.75
TemporalLobe9.7
Testis7.5
TestisGermCell7.45
TestisIntersitial11.2
TestisLeydigCell10.75
TestisSeminiferousTubule8.4
Thalamus10.95
Thymus6.45
Thyroid40.3
Tongue12.2
Tonsil10.3
Trachea8.3
TrigeminalGanglion13.35
Uterus17.45
UterusCorpus13.6
WholeBlood12.65
Wholebrain7.65
colon49.35
pineal_day21.46
pineal_night28.72
retina12.525
small_intestine30.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P121686
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.21 ± 0.25
Basal Forebrain8.47 ± 0.12
Basal Part of Pons8.47 ± 0.25
Cerebellar Cortex8.45 ± 0.14
Cerebellar Nuclei8.63 ± 0.31
Claustrum8.06 ± 0.3
Epithalamus8.76 ± 0.23
Frontal Lobe8.43 ± 0.23
Globus Pallidus8.99 ± 0.12
Hypothalamus8.45 ± 0.31
Insula8.41 ± 0.11
Limbic Lobe8.23 ± 0.19
Mesencephalon8.42 ± 0.32
Myelencephalon8.39 ± 0.29
Occipital Lobe8.25 ± 0.26
Parietal Lobe8.37 ± 0.26
Pontine Tegmentum8.41 ± 0.2
Striatum8.53 ± 0.25
Subthalamus8.52 ± 0.16
Temporal Lobe8.37 ± 0.23
Thalamus8.41 ± 0.29
White Matter9.45 ± 0.16
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AIMP1_HUMAN_14 12 14 25 GAEADQIIEYLK PRIDE
AIMP1_HUMAN_166 21 166 186 KHPDADSLYVEEVDVGEIAPR PRIDE
AIMP1_HUMAN_187 18 187 204 TVVSGLVNHVPLEQMQNR PRIDE
AIMP1_HUMAN_2 9 2 10 ANNDAVLKR PRIDE
AIMP1_HUMAN_250 17 250 266 ITFDAFPGEPDKELNPK PRIDE
AIMP1_HUMAN_35 11 35 45 AILQATLREEK PRIDE
PAp00003166 16 220 235 GVLSQAMVMCASSPEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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