AutismKB 2.0

Annotation Detail for TIFA


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Basic Information Top
Gene Symbol:TIFA ( MGC20791,T2BP,T6BP,TIFAA )
Gene Full Name: TRAF-interacting protein with forkhead-associated domain
Band: 4q25
Quick LinksEntrez ID:92610; OMIM: 609028; Uniprot ID:TIFA_HUMAN; ENSEMBL ID: ENSG00000145365; HGNC ID: 19075
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus21 / 56401237
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal83 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone3 / 7165541
bone marrow1 / 4880120
brain8 / 11009897
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye8 / 21105437
heart1 / 8962611
intestine3 / 23447212
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph2 / 4427045
lymph node15 / 91610163
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate3 / 18934515
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach1 / 9661910
testis1 / 3304423
thymus2 / 8113124
thyroid0 / 474730 
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P350686
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.83 ± 0.79
Basal Forebrain3.45 ± 0.52
Basal Part of Pons5.34 ± 0.42
Cerebellar Cortex5.26 ± 0.33
Cerebellar Nuclei5.13 ± 0.72
Claustrum3.62 ± 1.09
Epithalamus4.13 ± 0.47
Frontal Lobe4.51 ± 0.73
Globus Pallidus3.42 ± 0.71
Hypothalamus3.83 ± 0.73
Insula4.32 ± 0.48
Limbic Lobe4.51 ± 0.86
Mesencephalon4.25 ± 0.77
Myelencephalon4.28 ± 0.82
Occipital Lobe5.17 ± 0.87
Parietal Lobe4.63 ± 0.71
Pontine Tegmentum4.28 ± 0.8
Striatum3.78 ± 0.53
Subthalamus4.6 ± 0.48
Temporal Lobe4.26 ± 0.71
Thalamus4.75 ± 0.61
White Matter2.75 ± 0.46
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018