AutismKB 2.0

Annotation Detail for STK17B


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Basic Information Top
Gene Symbol:STK17B ( DRAK2 )
Gene Full Name: serine/threonine kinase 17b
Band: 2q32.3
Quick LinksEntrez ID:9262; OMIM: 604727; Uniprot ID:ST17B_HUMAN; ENSEMBL ID: ENSG00000081320; HGNC ID: 11396
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus14 / 56401224
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor7 / 11424661
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma7 / 7175597
non-neoplasia2 / 9725020
normal126 / 336030737
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood8 / 12347864
bone4 / 7165555
bone marrow4 / 4880181
brain18 / 110098916
cervix0 / 481710 
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus2 / 2020998
eye3 / 21105414
heart0 / 896260 
intestine8 / 23447234
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung7 / 33697420
lymph1 / 4427022
lymph node31 / 91610338
mammary gland1 / 1532716
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta7 / 28082524
prostate5 / 18934526
salivary gland0 / 201550 
skin5 / 21057423
spleen3 / 5395255
stomach1 / 9661910
testis19 / 33044257
thymus9 / 81131110
thyroid0 / 474730 
tonsil2 / 16999117
trachea4 / 5241376
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217503_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte5.85
AdrenalCortex6.5
Adrenalgland5
Amygdala6.05
Appendix6.35
AtrioventricularNode4.95
BDCA4+_DentriticCells13.6
Bonemarrow6.15
BronchialEpithelialCells5.85
CD105+_Endothelial5.9
CD14+_Monocytes6.75
CD19+_BCells(neg._sel.)12.15
CD33+_Myeloid25.9
CD34+7.25
CD4+_Tcells6.9
CD56+_NKCells11.55
CD71+_EarlyErythroid5.6
CD8+_Tcells8.6
CardiacMyocytes8.75
Caudatenucleus5.3
Cerebellum4.8
CerebellumPeduncles6.8
CiliaryGanglion4.7
CingulateCortex8.3
Colorectaladenocarcinoma5.95
DorsalRootGanglion4.75
FetalThyroid5.75
Fetalbrain5.65
Fetalliver5.1
Fetallung4.7
GlobusPallidus4.4
Heart8.35
Hypothalamus6.2
Kidney4.95
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.8
Liver7.8
Lung6.5
Lymphnode8.6
Lymphoma_burkitts(Daudi)7.75
Lymphoma_burkitts(Raji)8.5
MedullaOblongata5.35
OccipitalLobe5.25
OlfactoryBulb4.65
Ovary4
Pancreas4.8
PancreaticIslet6.3
ParietalLobe6.4
Pituitary6.8
Placenta5.85
Pons5.65
PrefrontalCortex7.1
Prostate6.75
Salivarygland4.8
SkeletalMuscle7.2
Skin5
SmoothMuscle6.55
Spinalcord6.25
SubthalamicNucleus5.4
SuperiorCervicalGanglion7.3
TemporalLobe5.45
Testis5.05
TestisGermCell4.75
TestisIntersitial4.9
TestisLeydigCell6
TestisSeminiferousTubule5
Thalamus6.05
Thymus4.75
Thyroid7.05
Tongue6.05
Tonsil5.85
Trachea4.9
TrigeminalGanglion6
Uterus4.75
UterusCorpus5.55
WholeBlood44.75
Wholebrain4.8
colon5.9
pineal_day7.16
pineal_night7.02
retina7.075
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P636882
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.66 ± 0.91
Basal Forebrain2.06 ± 0.27
Basal Part of Pons1.99 ± 0.38
Cerebellar Cortex3.24 ± 0.51
Cerebellar Nuclei2.42 ± 0.57
Claustrum2.6 ± 0.86
Epithalamus1.86 ± 0.83
Frontal Lobe2.48 ± 0.82
Globus Pallidus2.1 ± 0.7
Hypothalamus2.32 ± 0.54
Insula2.44 ± 0.73
Limbic Lobe2.72 ± 0.89
Mesencephalon2.51 ± 0.7
Myelencephalon2.38 ± 0.71
Occipital Lobe2.62 ± 0.83
Parietal Lobe2.42 ± 0.79
Pontine Tegmentum2.58 ± 0.94
Striatum1.85 ± 0.65
Subthalamus2.49 ± 0.73
Temporal Lobe2.24 ± 0.74
Thalamus2.28 ± 0.7
White Matter1.81 ± 0.37
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00041166 9 185 193 KIGHACELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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