AutismKB 2.0

Annotation Detail for WDR85


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Basic Information Top
Gene Symbol:WDR85 ( C9orf112,FLJ90634,RP11-48C7.3 )
Gene Full Name: WD repeat domain 85
Band: 9q34.3
Quick LinksEntrez ID:92715; OMIM: 613210; Uniprot ID:WDR85_HUMAN; ENSEMBL ID: ENSG00000148399; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus10 / 56401217
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma11 / 82823132
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor8 / 26384530
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor12 / 103127116
lymphoma4 / 7175555
non-neoplasia6 / 9725061
normal126 / 336030737
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS21 / 125680167
prostate cancer5 / 10268048
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites8 / 40015199
bladder3 / 29757100
blood3 / 12347824
bone11 / 71655153
bone marrow0 / 488010 
brain47 / 110098942
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine15 / 23447263
kidney5 / 21177723
larynx1 / 2414541
liver3 / 20774314
lung21 / 33697462
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate12 / 18934563
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach3 / 9661931
testis20 / 33044260
thymus7 / 8113186
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P329016
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.37 ± 0.65
Basal Forebrain5.08 ± 0.23
Basal Part of Pons4.9 ± 0.45
Cerebellar Cortex5.03 ± 0.45
Cerebellar Nuclei4.59 ± 0.38
Claustrum5.31 ± 0.62
Epithalamus4.79 ± 0.33
Frontal Lobe4.78 ± 0.47
Globus Pallidus5.51 ± 0.25
Hypothalamus4.44 ± 0.57
Insula4.78 ± 0.58
Limbic Lobe5.19 ± 0.61
Mesencephalon4.8 ± 0.57
Myelencephalon5.03 ± 0.59
Occipital Lobe5.49 ± 0.59
Parietal Lobe5.02 ± 0.46
Pontine Tegmentum5.08 ± 0.56
Striatum5.33 ± 0.64
Subthalamus4.26 ± 0.09
Temporal Lobe4.92 ± 0.47
Thalamus5.19 ± 0.55
White Matter6.08 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr85CBCerebellum9.81
13
Wdr85CTXCerebral cortex25.6
21.11
Wdr85HIPHippocampal region29.89
35.99
Wdr85HPFHippocampal formation34.62
36.7
Wdr85HYHypothalamus17.45
14.64
Wdr85LSXLateral septal complex1.64
1.28
Wdr85MBMidbrain7.8
7.68
Wdr85MYMedulla19.31
22.71
Wdr85OLFOlfactory bulb41.81
36.6
Wdr85PPons22.83
25.97
Wdr85PALPallidum11.39
11.71
Wdr85RHPRetrohippocampal region45.87
40.6
Wdr85sAMYStriatum-like amygdalar nuclei15.42
11.77
Wdr85STRStriatum10.37
8.05
Wdr85STRdStriatum dorsal region7.37
5.67
Wdr85STRvStriatum ventral region19.57
14.58
Wdr85THThalamus13.21
11.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018