AutismKB 2.0

Annotation Detail for DNER


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNER ( UNQ26,bet )
Gene Full Name: delta/notch-like EGF repeat containing
Band: 2q36.3
Quick LinksEntrez ID:92737; OMIM: 607299; Uniprot ID:DNER_HUMAN; ENSEMBL ID: ENSG00000187957; HGNC ID: 24456
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus28 / 56401249
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor5 / 34366145
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor12 / 26384545
glioma23 / 106883215
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal118 / 336030735
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain144 / 1100989130
cervix5 / 48171103
connective tissue5 / 14925533
ear5 / 16212308
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine0 / 2344720 
kidney7 / 21177733
larynx1 / 2414541
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_618_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.74 ± 0.39
Basal Forebrain5.99 ± 0.34
Basal Part of Pons6.07 ± 0.4
Cerebellar Cortex6.4 ± 0.23
Cerebellar Nuclei6.43 ± 0.4
Claustrum5.52 ± 0.6
Epithalamus6.38 ± 0.39
Frontal Lobe5.96 ± 0.47
Globus Pallidus6.95 ± 0.62
Hypothalamus6.38 ± 0.39
Insula5.88 ± 0.34
Limbic Lobe5.7 ± 0.54
Mesencephalon6.2 ± 0.39
Myelencephalon6.06 ± 0.39
Occipital Lobe5.83 ± 0.47
Parietal Lobe5.96 ± 0.44
Pontine Tegmentum6.04 ± 0.46
Striatum5.53 ± 0.63
Subthalamus6.04 ± 0.5
Temporal Lobe5.98 ± 0.4
Thalamus6.55 ± 0.37
White Matter7.46 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DnerCBCerebellum58.56
100
DnerCTXCerebral cortex79.86
77.01
DnerHIPHippocampal region65.87
87.27
DnerHPFHippocampal formation85.59
99.14
DnerHYHypothalamus100
100
DnerLSXLateral septal complex100
100
DnerMBMidbrain89.11
89.03
DnerMYMedulla90.03
100
DnerOLFOlfactory bulb100
100
DnerPPons85.95
95.65
DnerPALPallidum92.55
98.69
DnerRHPRetrohippocampal region100
100
DnersAMYStriatum-like amygdalar nuclei100
100
DnerSTRStriatum51.06
47.25
DnerSTRdStriatum dorsal region22.09
24.08
DnerSTRvStriatum ventral region59.88
54.46
DnerTHThalamus67.96
62.09
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018