AutismKB 2.0

Annotation Detail for TAAR2


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Basic Information Top
Gene Symbol:TAAR2 ( GPR58 )
Gene Full Name: trace amine associated receptor 2
Band: 6q23.2
Quick LinksEntrez ID:9287; OMIM: 604849; Uniprot ID:TAAR2_HUMAN; ENSEMBL ID: ENSG00000146378; HGNC ID: 4514
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221394_at
Cell line Expression level Expression bar
721_B_lymphoblasts3.2
Adipocyte2.55
AdrenalCortex2.6
Adrenalgland2.15
Amygdala2.75
Appendix2.95
AtrioventricularNode3.2
BDCA4+_DentriticCells2.95
Bonemarrow2.55
BronchialEpithelialCells2.5
CD105+_Endothelial2.6
CD14+_Monocytes2.75
CD19+_BCells(neg._sel.)2.75
CD33+_Myeloid3.35
CD34+3.35
CD4+_Tcells2.8
CD56+_NKCells3.2
CD71+_EarlyErythroid2.4
CD8+_Tcells2.5
CardiacMyocytes3.35
Caudatenucleus2.35
Cerebellum2.05
CerebellumPeduncles2.9
CiliaryGanglion1.9
CingulateCortex2.7
Colorectaladenocarcinoma2.6
DorsalRootGanglion2
FetalThyroid2.55
Fetalbrain2.55
Fetalliver2.2
Fetallung2.1
GlobusPallidus1.95
Heart3.3
Hypothalamus2.8
Kidney2.05
Leukemia_chronicMyelogenousK-5622.35
Leukemia_promyelocytic-HL-602.3
Leukemialymphoblastic(MOLT-4)2.1
Liver3.45
Lung2.85
Lymphnode2.25
Lymphoma_burkitts(Daudi)3.25
Lymphoma_burkitts(Raji)3.65
MedullaOblongata2.35
OccipitalLobe2.3
OlfactoryBulb2.05
Ovary1.75
Pancreas2.1
PancreaticIslet2.7
ParietalLobe2.7
Pituitary3.05
Placenta2.65
Pons2.45
PrefrontalCortex3.25
Prostate3
Salivarygland2.1
SkeletalMuscle2.9
Skin2
SmoothMuscle2.95
Spinalcord2.75
SubthalamicNucleus2.35
SuperiorCervicalGanglion3.05
TemporalLobe2.35
Testis2.2
TestisGermCell2.15
TestisIntersitial2.2
TestisLeydigCell2.55
TestisSeminiferousTubule2.25
Thalamus2.65
Thymus2
Thyroid3.25
Tongue2.55
Tonsil2.5
Trachea2.15
TrigeminalGanglion2.7
Uterus2.1
UterusCorpus2.25
WholeBlood2.8
Wholebrain2.2
colon2.6
pineal_day3.44
pineal_night3.16
retina3.125
small_intestine2.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P70733
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.98 ± 0.73
Basal Forebrain4.43 ± 0.69
Basal Part of Pons4.61 ± 0.47
Cerebellar Cortex4.29 ± 0.8
Cerebellar Nuclei4.34 ± 0.72
Claustrum4.81 ± 0.83
Epithalamus3.98 ± 0.68
Frontal Lobe4.52 ± 0.81
Globus Pallidus5.15 ± 0.75
Hypothalamus3.92 ± 0.91
Insula4.25 ± 1.08
Limbic Lobe4.71 ± 0.91
Mesencephalon4.3 ± 0.8
Myelencephalon4.62 ± 0.79
Occipital Lobe4.65 ± 0.79
Parietal Lobe4.5 ± 0.82
Pontine Tegmentum4.44 ± 0.71
Striatum4.69 ± 0.87
Subthalamus3.48 ± 1.66
Temporal Lobe4.46 ± 0.95
Thalamus4.59 ± 0.73
White Matter4.42 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Taar2CBCerebellum2.51
3.89
Taar2CTXCerebral cortex2.17
3
Taar2HIPHippocampal region1.25
1.36
Taar2HPFHippocampal formation1.92
1.64
Taar2HYHypothalamus0.1
0.22
Taar2LSXLateral septal complex0.03
0
Taar2MBMidbrain1.02
1.57
Taar2MYMedulla3.44
4.06
Taar2OLFOlfactory bulb2.45
2.83
Taar2PPons0.93
1.37
Taar2PALPallidum0.32
0.45
Taar2RHPRetrohippocampal region3.48
2.29
Taar2sAMYStriatum-like amygdalar nuclei0.29
0.59
Taar2STRStriatum0.49
0.48
Taar2STRdStriatum dorsal region0.55
0.48
Taar2STRvStriatum ventral region0.2
0.15
Taar2THThalamus0.75
0.76
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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