AutismKB 2.0

Annotation Detail for GPR56


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Basic Information Top
Gene Symbol:GPR56 ( BFPP,DKFZp781L1398,TM7LN4,TM7XN1 )
Gene Full Name: G protein-coupled receptor 56
Band: 16q13
Quick LinksEntrez ID:9289; OMIM: 604110; Uniprot ID:GPR56_HUMAN; ENSEMBL ID: ENSG00000205336; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus135 / 564012239
neonate7 / 31097225
infant0 / 236200 
juvenile3 / 5555653
adult425 / 1939121219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor28 / 94178297
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor25 / 114246218
esophageal tumor2 / 17290115
gastrointestinal tumor9 / 11936975
germ cell tumor154 / 263845583
glioma49 / 106883458
head and neck tumor76 / 136302557
kidney tumor17 / 68959246
leukemia16 / 95842166
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal860 / 3360307255
ovarian tumor20 / 76682260
pancreatic tumor22 / 104616210
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor91 / 124949728
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder2 / 2975767
blood7 / 12347856
bone0 / 716550 
bone marrow1 / 4880120
brain669 / 1100989607
cervix6 / 48171124
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus2 / 2020998
eye16 / 21105475
heart1 / 8962611
intestine33 / 234472140
kidney42 / 211777198
larynx1 / 2414541
liver6 / 20774328
lung12 / 33697435
lymph0 / 442700 
lymph node15 / 91610163
mammary gland32 / 153271208
mouth38 / 67052566
muscle9 / 10771583
nerve0 / 157680 
ovary22 / 102051215
pancreas37 / 214812172
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta100 / 280825356
prostate11 / 18934558
salivary gland2 / 2015599
skin93 / 210574441
spleen1 / 5395218
stomach6 / 9661962
testis294 / 330442889
thymus41 / 81131505
thyroid52 / 474731095
tonsil0 / 169990 
trachea55 / 524131049
umbilical cord6 / 13680438
uterus33 / 232878141
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206582_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte5.7
AdrenalCortex6.45
Adrenalgland5
Amygdala9.9
Appendix5.9
AtrioventricularNode4.6
BDCA4+_DentriticCells5.75
Bonemarrow5.8
BronchialEpithelialCells5.55
CD105+_Endothelial5.65
CD14+_Monocytes6
CD19+_BCells(neg._sel.)5.9
CD33+_Myeloid7.05
CD34+6.9
CD4+_Tcells5.9
CD56+_NKCells72.8
CD71+_EarlyErythroid5.3
CD8+_Tcells5.55
CardiacMyocytes7.8
Caudatenucleus5.25
Cerebellum4.7
CerebellumPeduncles6.6
CiliaryGanglion4.25
CingulateCortex5.95
Colorectaladenocarcinoma8.35
DorsalRootGanglion4.65
FetalThyroid5.6
Fetalbrain6.3
Fetalliver5
Fetallung4.65
GlobusPallidus4.45
Heart7.6
Hypothalamus7.6
Kidney5.25
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)5.2
Liver7.8
Lung6.3
Lymphnode4.8
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)7.9
MedullaOblongata5.2
OccipitalLobe5.2
OlfactoryBulb4.55
Ovary4
Pancreas4.75
PancreaticIslet6.55
ParietalLobe6.2
Pituitary7.65
Placenta9.15
Pons5.6
PrefrontalCortex13.15
Prostate6.7
Salivarygland4.65
SkeletalMuscle7.35
Skin4.8
SmoothMuscle6.35
Spinalcord6.2
SubthalamicNucleus5.35
SuperiorCervicalGanglion8.6
TemporalLobe5.35
Testis4.95
TestisGermCell4.85
TestisIntersitial4.85
TestisLeydigCell5.75
TestisSeminiferousTubule5
Thalamus5.85
Thymus4.35
Thyroid36.7
Tongue5.75
Tonsil5.6
Trachea4.85
TrigeminalGanglion6.45
Uterus4.6
UterusCorpus5.3
WholeBlood6.25
Wholebrain4.95
colon5.75
pineal_day7.08
pineal_night6.96
retina6.85
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_296_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.78 ± 0.73
Basal Forebrain3.49 ± 0.44
Basal Part of Pons3.46 ± 0.47
Cerebellar Cortex3.4 ± 0.53
Cerebellar Nuclei3.78 ± 0.46
Claustrum3.85 ± 0.71
Epithalamus3.42 ± 0.34
Frontal Lobe3.63 ± 0.52
Globus Pallidus3.7 ± 0.36
Hypothalamus3.17 ± 0.42
Insula3.57 ± 0.39
Limbic Lobe3.58 ± 0.56
Mesencephalon3.69 ± 0.49
Myelencephalon3.61 ± 0.59
Occipital Lobe3.86 ± 0.62
Parietal Lobe3.48 ± 0.57
Pontine Tegmentum3.55 ± 0.58
Striatum3.86 ± 0.55
Subthalamus3.74 ± 0.26
Temporal Lobe3.57 ± 0.53
Thalamus3.84 ± 0.56
White Matter2.99 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr56CBCerebellum11.25
13.35
Gpr56CTXCerebral cortex7.26
5.21
Gpr56HIPHippocampal region13.76
15.06
Gpr56HPFHippocampal formation12.11
11.95
Gpr56HYHypothalamus53.22
45.33
Gpr56LSXLateral septal complex22.67
20.53
Gpr56MBMidbrain12.2
11.52
Gpr56MYMedulla17.61
18.29
Gpr56OLFOlfactory bulb42.04
38.24
Gpr56PPons17.1
16.79
Gpr56PALPallidum23.37
19.45
Gpr56RHPRetrohippocampal region9.61
7.95
Gpr56sAMYStriatum-like amygdalar nuclei34.69
27.86
Gpr56STRStriatum14.63
12.13
Gpr56STRdStriatum dorsal region7.67
6.41
Gpr56STRvStriatum ventral region22.63
16.48
Gpr56THThalamus12.44
10.89
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00803417 24 56 79 ISIENSEEALTVHAPFPAAHPASR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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