AutismKB 2.0

Annotation Detail for SRSF11


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Basic Information Top
Gene Symbol:SRSF11 ( DKFZp686M13204,FLJ18226,NET2,SFRS11,dJ677H15.2,p54 )
Gene Full Name: serine/arginine-rich splicing factor 11
Band: 1p31.1
Quick LinksEntrez ID:9295; OMIM: 602010; Uniprot ID:SRS11_HUMAN; ENSEMBL ID: ENSG00000116754; HGNC ID: 10782
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body23 / 70761325
blastocyst26 / 62319417
fetus97 / 564012171
neonate1 / 3109732
infant2 / 2362084
juvenile9 / 55556161
adult277 / 1939121142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma6 / 17475343
breast (mammary gland) tumor10 / 94178106
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor9 / 11424678
esophageal tumor4 / 17290231
gastrointestinal tumor20 / 119369167
germ cell tumor59 / 263845223
glioma8 / 10688374
head and neck tumor11 / 13630280
kidney tumor9 / 68959130
leukemia12 / 95842125
liver tumor14 / 96359145
lung tumor4 / 10312738
lymphoma2 / 7175527
non-neoplasia18 / 97250185
normal505 / 3360307150
ovarian tumor11 / 76682143
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer17 / 102680165
retinoblastoma3 / 4635664
skin tumor9 / 12494972
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor18 / 90257199
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland11 / 33197331
ascites8 / 40015199
bladder12 / 29757403
blood14 / 123478113
bone8 / 71655111
bone marrow7 / 48801143
brain123 / 1100989111
cervix1 / 4817120
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue75 / 215722347
esophagus4 / 20209197
eye23 / 211054108
heart15 / 89626167
intestine25 / 234472106
kidney24 / 211777113
larynx3 / 24145124
liver41 / 207743197
lung73 / 336974216
lymph1 / 4427022
lymph node17 / 91610185
mammary gland18 / 153271117
mouth7 / 67052104
muscle14 / 107715129
nerve1 / 1576863
ovary15 / 102051146
pancreas23 / 214812107
parathyroid3 / 20539146
pharynx2 / 4132848
pituitary gland3 / 16585180
placenta41 / 280825145
prostate26 / 189345137
salivary gland4 / 20155198
skin13 / 21057461
spleen7 / 53952129
stomach13 / 96619134
testis67 / 330442202
thymus25 / 81131308
thyroid3 / 4747363
tonsil0 / 169990 
trachea11 / 52413209
umbilical cord0 / 136800 
uterus50 / 232878214
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200686_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1111.2
Adipocyte261.5
AdrenalCortex341.25
Adrenalgland230.8
Amygdala580.2
Appendix296.2
AtrioventricularNode127.7
BDCA4+_DentriticCells803.9
Bonemarrow91.6
BronchialEpithelialCells330.15
CD105+_Endothelial943.45
CD14+_Monocytes641.35
CD19+_BCells(neg._sel.)709.2
CD33+_Myeloid633
CD34+901.85
CD4+_Tcells1422.1
CD56+_NKCells855.7
CD71+_EarlyErythroid316.35
CD8+_Tcells1594.65
CardiacMyocytes141.3
Caudatenucleus247.45
Cerebellum167.35
CerebellumPeduncles173.3
CiliaryGanglion142.75
CingulateCortex310.65
Colorectaladenocarcinoma330.7
DorsalRootGanglion175.65
FetalThyroid423.85
Fetalbrain601.7
Fetalliver264
Fetallung584.45
GlobusPallidus184.75
Heart20.65
Hypothalamus503.6
Kidney111.65
Leukemia_chronicMyelogenousK-562738.95
Leukemia_promyelocytic-HL-60883.7
Leukemialymphoblastic(MOLT-4)706.15
Liver58.95
Lung163.15
Lymphnode722.9
Lymphoma_burkitts(Daudi)742.35
Lymphoma_burkitts(Raji)790.75
MedullaOblongata228.2
OccipitalLobe318.05
OlfactoryBulb313.1
Ovary251.95
Pancreas260.6
PancreaticIslet373.9
ParietalLobe257.25
Pituitary783.2
Placenta162
Pons195.65
PrefrontalCortex899.75
Prostate432.5
Salivarygland385.95
SkeletalMuscle104.2
Skin174.95
SmoothMuscle301
Spinalcord328.65
SubthalamicNucleus252.8
SuperiorCervicalGanglion113.65
TemporalLobe210.8
Testis276.5
TestisGermCell602.2
TestisIntersitial325.1
TestisLeydigCell410.4
TestisSeminiferousTubule444.35
Thalamus246.7
Thymus258.15
Thyroid1042.85
Tongue277.4
Tonsil371.1
Trachea290.45
TrigeminalGanglion132.35
Uterus884.45
UterusCorpus329.55
WholeBlood293.1
Wholebrain155.75
colon347.6
pineal_day547.46
pineal_night556.54
retina341.95
small_intestine259.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P11664
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.19 ± 0.21
Basal Forebrain9.36 ± 0.16
Basal Part of Pons9.46 ± 0.14
Cerebellar Cortex9.63 ± 0.14
Cerebellar Nuclei9.3 ± 0.14
Claustrum9.32 ± 0.23
Epithalamus9.67 ± 0.27
Frontal Lobe9.3 ± 0.22
Globus Pallidus9.28 ± 0.17
Hypothalamus9.38 ± 0.33
Insula9.39 ± 0.19
Limbic Lobe9.33 ± 0.27
Mesencephalon9.37 ± 0.22
Myelencephalon9.35 ± 0.25
Occipital Lobe9.63 ± 0.3
Parietal Lobe9.37 ± 0.24
Pontine Tegmentum9.32 ± 0.25
Striatum9.35 ± 0.28
Subthalamus9.52 ± 0.21
Temporal Lobe9.4 ± 0.24
Thalamus9.32 ± 0.18
White Matter10.21 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sfrs11CBCerebellum100
100
Sfrs11CTXCerebral cortex100
100
Sfrs11HIPHippocampal region100
100
Sfrs11HPFHippocampal formation100
100
Sfrs11HYHypothalamus100
100
Sfrs11LSXLateral septal complex100
100
Sfrs11MBMidbrain100
100
Sfrs11MYMedulla100
100
Sfrs11OLFOlfactory bulb100
100
Sfrs11PPons100
100
Sfrs11PALPallidum100
100
Sfrs11RHPRetrohippocampal region100
100
Sfrs11sAMYStriatum-like amygdalar nuclei100
100
Sfrs11STRStriatum100
100
Sfrs11STRdStriatum dorsal region100
100
Sfrs11STRvStriatum ventral region100
100
Sfrs11THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063635 17 104 120 ALIVVPYAEGVIPDEAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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