AutismKB 2.0

Annotation Detail for NAPRT1


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Basic Information Top
Gene Symbol:NAPRT1 ( PP3856 )
Gene Full Name: nicotinate phosphoribosyltransferase domain containing 1
Band: 8q24.3
Quick LinksEntrez ID:93100; OMIM: 611552; Uniprot ID:PNCB_HUMAN; ENSEMBL ID: ENSG00000147813; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor20 / 114246175
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor8 / 26384530
glioma14 / 106883130
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal73 / 336030721
ovarian tumor3 / 7668239
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow0 / 488010 
brain23 / 110098920
cervix5 / 48171103
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye12 / 21105456
heart1 / 8962611
intestine32 / 234472136
kidney1 / 2117774
larynx0 / 241450 
liver9 / 20774343
lung8 / 33697423
lymph1 / 4427022
lymph node4 / 9161043
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate3 / 18934515
salivary gland3 / 20155148
skin9 / 21057442
spleen0 / 539520 
stomach13 / 96619134
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P43238
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.42 ± 0.64
Basal Forebrain3.39 ± 0.67
Basal Part of Pons3.54 ± 0.55
Cerebellar Cortex3.67 ± 0.52
Cerebellar Nuclei3.37 ± 0.41
Claustrum3.6 ± 0.68
Epithalamus3.27 ± 0.66
Frontal Lobe3.45 ± 0.53
Globus Pallidus2.79 ± 0.52
Hypothalamus3.27 ± 0.81
Insula3.58 ± 0.55
Limbic Lobe3.35 ± 0.55
Mesencephalon3.49 ± 0.61
Myelencephalon3.5 ± 0.56
Occipital Lobe3.36 ± 0.52
Parietal Lobe3.44 ± 0.64
Pontine Tegmentum3.2 ± 0.57
Striatum3.42 ± 0.51
Subthalamus3.06 ± 0.97
Temporal Lobe3.46 ± 0.5
Thalamus3.44 ± 0.55
White Matter2.89 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Naprt1CBCerebellum4.7
5.07
Naprt1LSXLateral septal complex0.77
0.92
Naprt1MYMedulla4.9
5.95
Naprt1STRdStriatum dorsal region0.62
0.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009607 14 48 61 CPFGGAFALAAGLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018