AutismKB 2.0

Annotation Detail for TRIP4


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Basic Information Top
Gene Symbol:TRIP4 ( ASC-1,HsT17391 )
Gene Full Name: thyroid hormone receptor interactor 4
Band: 15q22.31
Quick LinksEntrez ID:9325; OMIM: 604501; Uniprot ID:TRIP4_HUMAN; ENSEMBL ID: ENSG00000103671; HGNC ID: 12310
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus22 / 56401239
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult104 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor12 / 114246105
esophageal tumor4 / 17290231
gastrointestinal tumor1 / 1193698
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor4 / 10312738
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal136 / 336030740
ovarian tumor5 / 7668265
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor25 / 125191199
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood2 / 12347816
bone5 / 7165569
bone marrow2 / 4880140
brain26 / 110098923
cervix0 / 481710 
connective tissue27 / 149255180
ear2 / 16212123
embryonic tissue7 / 21572232
esophagus4 / 20209197
eye5 / 21105423
heart4 / 8962644
intestine24 / 234472102
kidney8 / 21177737
larynx0 / 241450 
liver6 / 20774328
lung15 / 33697444
lymph3 / 4427067
lymph node6 / 9161065
mammary gland2 / 15327113
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary7 / 10205168
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach3 / 9661931
testis11 / 33044233
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203732_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.95
Adipocyte5.95
AdrenalCortex6.35
Adrenalgland5.15
Amygdala6.35
Appendix6.2
AtrioventricularNode4.7
BDCA4+_DentriticCells52.85
Bonemarrow5.35
BronchialEpithelialCells16.95
CD105+_Endothelial25.45
CD14+_Monocytes79.55
CD19+_BCells(neg._sel.)22.55
CD33+_Myeloid43.35
CD34+23.15
CD4+_Tcells11.25
CD56+_NKCells94.55
CD71+_EarlyErythroid13.4
CD8+_Tcells20.05
CardiacMyocytes8.5
Caudatenucleus5.35
Cerebellum4.85
CerebellumPeduncles6.45
CiliaryGanglion5.55
CingulateCortex6.15
Colorectaladenocarcinoma6.1
DorsalRootGanglion4.7
FetalThyroid24.3
Fetalbrain8.05
Fetalliver5.25
Fetallung10.4
GlobusPallidus4.45
Heart7.75
Hypothalamus6.6
Kidney4.85
Leukemia_chronicMyelogenousK-5628.3
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.55
Liver7.8
Lung6.5
Lymphnode5.7
Lymphoma_burkitts(Daudi)7.75
Lymphoma_burkitts(Raji)8.4
MedullaOblongata5.45
OccipitalLobe4.5
OlfactoryBulb4.85
Ovary4.1
Pancreas4.65
PancreaticIslet6.9
ParietalLobe6.3
Pituitary7.7
Placenta8.25
Pons5.75
PrefrontalCortex7.25
Prostate7.3
Salivarygland4.9
SkeletalMuscle7.25
Skin4.85
SmoothMuscle16.35
Spinalcord6.5
SubthalamicNucleus5.6
SuperiorCervicalGanglion6.9
TemporalLobe5.5
Testis5.15
TestisGermCell6
TestisIntersitial7.65
TestisLeydigCell6
TestisSeminiferousTubule5.2
Thalamus5.1
Thymus5.1
Thyroid21.55
Tongue7.5
Tonsil6
Trachea4.95
TrigeminalGanglion6.2
Uterus6.2
UterusCorpus5.6
WholeBlood27.45
Wholebrain4.55
colon6.1
pineal_day20.8
pineal_night13.82
retina8.425
small_intestine6.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12193_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.38 ± 0.24
Basal Forebrain6.22 ± 0.19
Basal Part of Pons6.21 ± 0.25
Cerebellar Cortex6.41 ± 0.19
Cerebellar Nuclei6.45 ± 0.27
Claustrum5.98 ± 0.53
Epithalamus6.62 ± 0.31
Frontal Lobe6.3 ± 0.26
Globus Pallidus6.59 ± 0.19
Hypothalamus6.16 ± 0.43
Insula6.39 ± 0.23
Limbic Lobe6.27 ± 0.3
Mesencephalon6.34 ± 0.31
Myelencephalon6.29 ± 0.29
Occipital Lobe6.4 ± 0.3
Parietal Lobe6.3 ± 0.27
Pontine Tegmentum6.28 ± 0.29
Striatum6.38 ± 0.25
Subthalamus6.59 ± 0.29
Temporal Lobe6.26 ± 0.26
Thalamus6.22 ± 0.26
White Matter7.17 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trip4CBCerebellum42.91
32.66
Trip4CTXCerebral cortex46.13
30.13
Trip4HIPHippocampal region58.51
36.07
Trip4HPFHippocampal formation51.75
33.84
Trip4HYHypothalamus57.38
34.59
Trip4LSXLateral septal complex39.66
24.69
Trip4MBMidbrain36.64
24.2
Trip4MYMedulla66.7
48.28
Trip4OLFOlfactory bulb60.55
42.47
Trip4PPons55.05
40.1
Trip4PALPallidum45.81
28.88
Trip4RHPRetrohippocampal region40.66
29.73
Trip4sAMYStriatum-like amygdalar nuclei53.26
32.34
Trip4STRStriatum46.07
26.03
Trip4STRdStriatum dorsal region41.02
23.11
Trip4STRvStriatum ventral region63.7
32.79
Trip4THThalamus40.02
23.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072009 15 475 489 KPSPQEVSELQATYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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