AutismKB 2.0

Annotation Detail for TAOK2


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Basic Information Top
Gene Symbol:TAOK2 ( KIAA0881,MAP3K17,PSK,PSK1,PSK1-BETA,TAO1,TAO2 )
Gene Full Name: TAO kinase 2
Band: 16p11.2
Quick LinksEntrez ID:9344; OMIM: 613199; Uniprot ID:TAOK2_HUMAN; ENSEMBL ID: ENSG00000149930; HGNC ID: 16835
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma3 / 17475171
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor10 / 26384537
glioma9 / 10688384
head and neck tumor17 / 136302124
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal93 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow4 / 4880181
brain40 / 110098936
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine14 / 23447259
kidney6 / 21177728
larynx1 / 2414541
liver1 / 2077434
lung15 / 33697444
lymph0 / 442700 
lymph node4 / 9161043
mammary gland9 / 15327158
mouth2 / 6705229
muscle1 / 1077159
nerve3 / 15768190
ovary7 / 10205168
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta9 / 28082532
prostate6 / 18934531
salivary gland7 / 20155347
skin5 / 21057423
spleen1 / 5395218
stomach4 / 9661941
testis8 / 33044224
thymus5 / 8113161
thyroid4 / 4747384
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204986_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.2
Adipocyte8.7
AdrenalCortex20.95
Adrenalgland8.95
Amygdala12.55
Appendix11.55
AtrioventricularNode7.1
BDCA4+_DentriticCells8.4
Bonemarrow9.45
BronchialEpithelialCells8.25
CD105+_Endothelial8.9
CD14+_Monocytes9.55
CD19+_BCells(neg._sel.)9.25
CD33+_Myeloid11.2
CD34+12.05
CD4+_Tcells9.4
CD56+_NKCells10.9
CD71+_EarlyErythroid8.9
CD8+_Tcells7.65
CardiacMyocytes12.8
Caudatenucleus8.7
Cerebellum7.5
CerebellumPeduncles10.15
CiliaryGanglion9.75
CingulateCortex11.35
Colorectaladenocarcinoma8.75
DorsalRootGanglion7.35
FetalThyroid10.25
Fetalbrain8.65
Fetalliver8.85
Fetallung7.15
GlobusPallidus6.85
Heart12.7
Hypothalamus9.05
Kidney8.9
Leukemia_chronicMyelogenousK-5627.95
Leukemia_promyelocytic-HL-607.8
Leukemialymphoblastic(MOLT-4)6.35
Liver17.4
Lung9.85
Lymphnode7.65
Lymphoma_burkitts(Daudi)11.35
Lymphoma_burkitts(Raji)12.45
MedullaOblongata8.2
OccipitalLobe7.85
OlfactoryBulb6.85
Ovary6.05
Pancreas7.55
PancreaticIslet9.5
ParietalLobe12.25
Pituitary11.6
Placenta9
Pons9.3
PrefrontalCortex11.05
Prostate10.35
Salivarygland7.15
SkeletalMuscle14.3
Skin6.95
SmoothMuscle9.95
Spinalcord9.4
SubthalamicNucleus9.9
SuperiorCervicalGanglion15.85
TemporalLobe8.85
Testis8.2
TestisGermCell7.6
TestisIntersitial7.45
TestisLeydigCell9.6
TestisSeminiferousTubule9.2
Thalamus9.45
Thymus6.95
Thyroid11
Tongue9
Tonsil8.8
Trachea7.35
TrigeminalGanglion14.15
Uterus6.35
UterusCorpus15.8
WholeBlood9.55
Wholebrain10.25
colon8.15
pineal_day11.4
pineal_night11.18
retina10.85
small_intestine7.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13177_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.76 ± 0.47
Basal Forebrain4.67 ± 0.55
Basal Part of Pons4.64 ± 0.49
Cerebellar Cortex4.38 ± 0.43
Cerebellar Nuclei4.41 ± 0.35
Claustrum4.44 ± 0.65
Epithalamus4.34 ± 0.59
Frontal Lobe4.47 ± 0.51
Globus Pallidus4.93 ± 0.2
Hypothalamus4.26 ± 0.22
Insula4.62 ± 0.5
Limbic Lobe4.76 ± 0.46
Mesencephalon4.5 ± 0.58
Myelencephalon4.62 ± 0.52
Occipital Lobe4.78 ± 0.41
Parietal Lobe4.48 ± 0.44
Pontine Tegmentum4.49 ± 0.52
Striatum4.99 ± 0.42
Subthalamus4.27 ± 0.32
Temporal Lobe4.54 ± 0.4
Thalamus4.46 ± 0.49
White Matter5.71 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Taok2CBCerebellum2.03
3.19
Taok2CTXCerebral cortex0.85
1.05
Taok2HIPHippocampal region0.58
0.85
Taok2HPFHippocampal formation0.59
0.9
Taok2HYHypothalamus0.52
0.81
Taok2LSXLateral septal complex0.44
0.23
Taok2MBMidbrain1.11
1.45
Taok2MYMedulla2.24
2.46
Taok2OLFOlfactory bulb0.76
0.78
Taok2PPons1.74
2.28
Taok2PALPallidum0.26
0.28
Taok2RHPRetrohippocampal region0.5
0.81
Taok2sAMYStriatum-like amygdalar nuclei0.51
0.29
Taok2STRStriatum0.25
0.24
Taok2STRdStriatum dorsal region0.14
0.16
Taok2STRvStriatum ventral region0.49
0.54
Taok2THThalamus1.05
1.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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