AutismKB 2.0

Annotation Detail for WDR67


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Basic Information Top
Gene Symbol:WDR67 ( Gm85,MGC104222,MGC126773,MGC138159,MGC21654 )
Gene Full Name: WD repeat domain 67
Band: 8q24.13
Quick LinksEntrez ID:93594; OMIM: NA; Uniprot ID:WDR67_HUMAN; ENSEMBL ID: ENSG00000156787; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal51 / 336030715
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain8 / 11009897
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye4 / 21105418
heart1 / 8962611
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node5 / 9161054
mammary gland7 / 15327145
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland2 / 2015599
skin2 / 2105749
spleen1 / 5395218
stomach1 / 9661910
testis8 / 33044224
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214061_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.1
Adipocyte7.2
AdrenalCortex8.55
Adrenalgland6.45
Amygdala8.95
Appendix8.55
AtrioventricularNode6.7
BDCA4+_DentriticCells8.45
Bonemarrow7.75
BronchialEpithelialCells7.1
CD105+_Endothelial11.55
CD14+_Monocytes8.15
CD19+_BCells(neg._sel.)8.1
CD33+_Myeloid9
CD34+20.55
CD4+_Tcells20.5
CD56+_NKCells106.75
CD71+_EarlyErythroid12.35
CD8+_Tcells41.9
CardiacMyocytes10.8
Caudatenucleus6.75
Cerebellum6.1
CerebellumPeduncles9
CiliaryGanglion5.95
CingulateCortex7.75
Colorectaladenocarcinoma7.5
DorsalRootGanglion6.4
FetalThyroid7.35
Fetalbrain7.55
Fetalliver6.7
Fetallung5.3
GlobusPallidus5.95
Heart11.55
Hypothalamus7.8
Kidney6.3
Leukemia_chronicMyelogenousK-56211.5
Leukemia_promyelocytic-HL-606.75
Leukemialymphoblastic(MOLT-4)21.95
Liver10.45
Lung7.8
Lymphnode6.9
Lymphoma_burkitts(Daudi)14.55
Lymphoma_burkitts(Raji)10.8
MedullaOblongata8.75
OccipitalLobe6.5
OlfactoryBulb5.7
Ovary5.35
Pancreas6.1
PancreaticIslet7.85
ParietalLobe8.05
Pituitary8.5
Placenta7.3
Pons9.65
PrefrontalCortex9.8
Prostate8.05
Salivarygland6.05
SkeletalMuscle10.75
Skin6.05
SmoothMuscle8.1
Spinalcord7.8
SubthalamicNucleus7
SuperiorCervicalGanglion10.8
TemporalLobe7.55
Testis6.2
TestisGermCell6.3
TestisIntersitial6.7
TestisLeydigCell7.9
TestisSeminiferousTubule6.45
Thalamus7.65
Thymus5.8
Thyroid8.4
Tongue8.05
Tonsil7.6
Trachea6.15
TrigeminalGanglion17.75
Uterus5.65
UterusCorpus7
WholeBlood8.8
Wholebrain5.55
colon7.4
pineal_day9.3
pineal_night9.54
retina8.85
small_intestine6.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13645_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.03 ± 0.6
Basal Forebrain4.96 ± 0.37
Basal Part of Pons5.11 ± 0.4
Cerebellar Cortex5.26 ± 0.25
Cerebellar Nuclei4.56 ± 0.44
Claustrum4.46 ± 0.44
Epithalamus5.03 ± 0.69
Frontal Lobe4.8 ± 0.39
Globus Pallidus4.19 ± 0.36
Hypothalamus4.65 ± 0.41
Insula4.98 ± 0.47
Limbic Lobe5.03 ± 0.57
Mesencephalon4.76 ± 0.52
Myelencephalon4.83 ± 0.48
Occipital Lobe5.07 ± 0.38
Parietal Lobe4.77 ± 0.49
Pontine Tegmentum4.83 ± 0.53
Striatum5.32 ± 0.49
Subthalamus4.78 ± 0.45
Temporal Lobe4.97 ± 0.4
Thalamus4.8 ± 0.37
White Matter3.9 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr67CBCerebellum7.5
8.8
Wdr67CTXCerebral cortex16.05
10.38
Wdr67HIPHippocampal region8.45
7.38
Wdr67HPFHippocampal formation8.55
6.9
Wdr67HYHypothalamus3.26
2.23
Wdr67LSXLateral septal complex2.3
1.68
Wdr67MBMidbrain8.96
7.82
Wdr67MYMedulla15.95
14.31
Wdr67OLFOlfactory bulb16.42
12
Wdr67PPons12.77
11.95
Wdr67PALPallidum4.13
3.25
Wdr67RHPRetrohippocampal region9.15
6.48
Wdr67sAMYStriatum-like amygdalar nuclei3.22
2.29
Wdr67STRStriatum3.31
2.55
Wdr67STRdStriatum dorsal region3.42
2.8
Wdr67STRvStriatum ventral region3.27
1.99
Wdr67THThalamus3.49
3.22
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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