AutismKB 2.0

Annotation Detail for PPIG


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Basic Information Top
Gene Symbol:PPIG ( CARS-Cyp,CYP,MGC133241,SCAF10,SRCyp )
Gene Full Name: peptidylprolyl isomerase G (cyclophilin G)
Band: 2q31.1
Quick LinksEntrez ID:9360; OMIM: 606093; Uniprot ID:PPIG_HUMAN; ENSEMBL ID: ENSG00000138398; HGNC ID: 14650
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus38 / 56401267
neonate1 / 3109732
infant2 / 2362084
juvenile4 / 5555671
adult161 / 193912183
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma17 / 82823205
colorectal tumor13 / 114246113
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor22 / 26384583
glioma7 / 10688365
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia13 / 95842135
liver tumor10 / 96359103
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal209 / 336030762
ovarian tumor4 / 7668252
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer5 / 10268048
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites6 / 40015149
bladder3 / 29757100
blood7 / 12347856
bone17 / 71655237
bone marrow8 / 48801163
brain39 / 110098935
cervix2 / 4817141
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye15 / 21105471
heart10 / 89626111
intestine26 / 234472110
kidney19 / 21177789
larynx0 / 241450 
liver22 / 207743105
lung30 / 33697489
lymph1 / 4427022
lymph node6 / 9161065
mammary gland12 / 15327178
mouth6 / 6705289
muscle9 / 10771583
nerve0 / 157680 
ovary6 / 10205158
pancreas26 / 214812121
parathyroid5 / 20539243
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta8 / 28082528
prostate21 / 189345110
salivary gland1 / 2015549
skin13 / 21057461
spleen2 / 5395237
stomach7 / 9661972
testis12 / 33044236
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus20 / 23287885
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208995_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.9
Adipocyte9.6
AdrenalCortex12.6
Adrenalgland9.4
Amygdala10.8
Appendix12.5
AtrioventricularNode12.65
BDCA4+_DentriticCells29.6
Bonemarrow11.55
BronchialEpithelialCells9.5
CD105+_Endothelial19.9
CD14+_Monocytes11.3
CD19+_BCells(neg._sel.)111
CD33+_Myeloid17.15
CD34+31.3
CD4+_Tcells33.35
CD56+_NKCells18.25
CD71+_EarlyErythroid10.35
CD8+_Tcells12.35
CardiacMyocytes16.85
Caudatenucleus9.05
Cerebellum8.25
CerebellumPeduncles12.7
CiliaryGanglion11.3
CingulateCortex11
Colorectaladenocarcinoma15.2
DorsalRootGanglion11
FetalThyroid10.4
Fetalbrain10
Fetalliver11
Fetallung9.95
GlobusPallidus8.2
Heart15.65
Hypothalamus10.65
Kidney9.35
Leukemia_chronicMyelogenousK-5629.55
Leukemia_promyelocytic-HL-609.4
Leukemialymphoblastic(MOLT-4)8.4
Liver15.6
Lung10.9
Lymphnode13.9
Lymphoma_burkitts(Daudi)13.9
Lymphoma_burkitts(Raji)16.45
MedullaOblongata9.3
OccipitalLobe9.1
OlfactoryBulb8.05
Ovary8.8
Pancreas10.1
PancreaticIslet11.5
ParietalLobe11.75
Pituitary12.1
Placenta8.5
Pons10.5
PrefrontalCortex12.55
Prostate11.8
Salivarygland8.8
SkeletalMuscle16.55
Skin11.85
SmoothMuscle11.6
Spinalcord11.05
SubthalamicNucleus10.5
SuperiorCervicalGanglion15.4
TemporalLobe9.9
Testis8.4
TestisGermCell8.5
TestisIntersitial9.95
TestisLeydigCell10.9
TestisSeminiferousTubule8.6
Thalamus10.8
Thymus7.35
Thyroid12.75
Tongue11.55
Tonsil10.6
Trachea8.3
TrigeminalGanglion17.5
Uterus11.4
UterusCorpus10.4
WholeBlood15.15
Wholebrain8.15
colon10
pineal_day13.32
pineal_night14.94
retina11.2
small_intestine9.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9914_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.11 ± 0.16
Basal Forebrain9.92 ± 0.32
Basal Part of Pons10.16 ± 0.27
Cerebellar Cortex10.24 ± 0.2
Cerebellar Nuclei9.92 ± 0.28
Claustrum10.35 ± 0.28
Epithalamus10.31 ± 0.37
Frontal Lobe10.01 ± 0.29
Globus Pallidus10.24 ± 0.24
Hypothalamus10.04 ± 0.28
Insula9.85 ± 0.35
Limbic Lobe10.01 ± 0.26
Mesencephalon10.04 ± 0.29
Myelencephalon10.03 ± 0.29
Occipital Lobe10.25 ± 0.31
Parietal Lobe10.09 ± 0.26
Pontine Tegmentum9.95 ± 0.31
Striatum9.95 ± 0.29
Subthalamus10.21 ± 0.11
Temporal Lobe9.97 ± 0.25
Thalamus9.99 ± 0.22
White Matter10.34 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PpigCBCerebellum2.62
3.67
PpigCTXCerebral cortex3.3
4.47
PpigHIPHippocampal region2.06
2.82
PpigHPFHippocampal formation2.45
2.56
PpigHYHypothalamus0.47
0.47
PpigLSXLateral septal complex0.26
0.28
PpigMBMidbrain1.44
1.46
PpigMYMedulla6.73
6.99
PpigOLFOlfactory bulb2.47
3.7
PpigPPons4.07
4.08
PpigPALPallidum1.57
1.4
PpigRHPRetrohippocampal region3.01
2.18
PpigsAMYStriatum-like amygdalar nuclei0.67
0.89
PpigSTRStriatum0.88
1.19
PpigSTRdStriatum dorsal region0.59
0.82
PpigSTRvStriatum ventral region2.25
2.85
PpigTHThalamus1.13
1.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000960 14 10 23 CFFDIAINNQPAGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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