Annotation Detail for ARHGAP18
Basic Information Top
| Gene Symbol: | ARHGAP18 ( FLJ25728,MGC126757,MGC138145,MacGAP,bA307O14.2 ) |
|---|---|
| Gene Full Name: | Rho GTPase activating protein 18 |
| Band: | 6q22.33 |
| Quick Links | Entrez ID:93663; OMIM: 613351; Uniprot ID:RHG18_HUMAN; ENSEMBL ID: ENSG00000146376; HGNC ID: 21035 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.486458
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 12 / 564012 | 21 | |
| neonate | 2 / 31097 | 64 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 59 / 1939121 | 30 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 10 / 114246 | 87 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 90 / 3360307 | 26 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 19 / 125191 | 151 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 3 / 123478 | 24 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 12 / 1100989 | 10 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 0 / 89626 | 0 | |
| intestine | 11 / 234472 | 46 | |
| kidney | 9 / 211777 | 42 | |
| larynx | 1 / 24145 | 41 | |
| liver | 8 / 207743 | 38 | |
| lung | 14 / 336974 | 41 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 6 / 41328 | 145 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 12 / 280825 | 42 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 11 / 210574 | 52 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 5 / 330442 | 15 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 12 / 52413 | 228 |  |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 24 / 232878 | 103 | |
| vascular | 10 / 51780 | 193 | |
Microarray in - Probe name: CUST_9954_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.37 ± 0.89 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.64 ± 0.6 | |
| Basal Part of Pons | 3.88 ± 1.04 | |
| Cerebellar Cortex | 3.78 ± 0.62 | |
| Cerebellar Nuclei | 4 ± 0.65 | |
| Claustrum | 4.89 ± 0.77 | |
| Epithalamus | 5.33 ± 0.66 | |
| Frontal Lobe | 4.12 ± 0.72 | |
| Globus Pallidus | 5.48 ± 0.38 | |
| Hypothalamus | 4.53 ± 0.73 | |
| Insula | 4.32 ± 0.59 | |
| Limbic Lobe | 4.28 ± 0.85 | |
| Mesencephalon | 4.19 ± 0.54 | |
| Myelencephalon | 4.29 ± 0.72 | |
| Occipital Lobe | 4.14 ± 0.68 | |
| Parietal Lobe | 4.13 ± 0.74 | |
| Pontine Tegmentum | 4.39 ± 0.75 | |
| Striatum | 4.5 ± 0.66 | |
| Subthalamus | 4.14 ± 0.84 | |
| Temporal Lobe | 4.31 ± 0.71 | |
| Thalamus | 4.79 ± 0.61 | |
| White Matter | 3.99 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Arhgap18 | CB | Cerebellum | 0.04 | |
| 0.1 | | |||
| Arhgap18 | CTX | Cerebral cortex | 1.65 | |
| 1.44 | | |||
| Arhgap18 | HIP | Hippocampal region | 1.39 | |
| 1.25 | | |||
| Arhgap18 | HPF | Hippocampal formation | 0.88 | |
| 0.77 | | |||
| Arhgap18 | HY | Hypothalamus | 3.73 | |
| 2.78 | | |||
| Arhgap18 | LSX | Lateral septal complex | 4.59 | |
| 3.22 | | |||
| Arhgap18 | MB | Midbrain | 0.25 | |
| 0.36 | | |||
| Arhgap18 | MY | Medulla | 0.01 | |
| 0.01 | | |||
| Arhgap18 | OLF | Olfactory bulb | 1.09 | |
| 1.24 | | |||
| Arhgap18 | P | Pons | 0.28 | |
| 0.63 | | |||
| Arhgap18 | PAL | Pallidum | 10.95 | |
| 7.69 | | |||
| Arhgap18 | RHP | Retrohippocampal region | 0.22 | |
| 0.21 | | |||
| Arhgap18 | sAMY | Striatum-like amygdalar nuclei | 9.99 | |
| 9.13 | | |||
| Arhgap18 | STR | Striatum | 3.23 | |
| 2.37 | | |||
| Arhgap18 | STRd | Striatum dorsal region | 0.99 | |
| 0.68 | | |||
| Arhgap18 | STRv | Striatum ventral region | 6.09 | |
| 3.93 | | |||
| Arhgap18 | TH | Thalamus | 2.06 | |
| 2.12 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp01154246 | 18 | 318 | 335 | DSGLFCVPLTALLEQDQR | Peptide Atlas |