AutismKB 2.0

Annotation Detail for CADPS2


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Basic Information Top
Gene Symbol:CADPS2 ( FLJ40851,KIAA1591 )
Gene Full Name: Ca++-dependent secretion activator 2
Band: 7q31.32
Quick LinksEntrez ID:93664; OMIM: 609978; Uniprot ID:CAPS2_HUMAN; ENSEMBL ID: ENSG00000081803; HGNC ID: 16018
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal72 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain44 / 110098939
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine6 / 23447225
kidney10 / 21177747
larynx0 / 241450 
liver3 / 20774314
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland1 / 2015549
skin4 / 21057418
spleen1 / 5395218
stomach1 / 9661910
testis1 / 3304423
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus20 / 23287885
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219572_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.45
Adipocyte5.05
AdrenalCortex6
Adrenalgland6.3
Amygdala13.25
Appendix5.15
AtrioventricularNode9.35
BDCA4+_DentriticCells5.45
Bonemarrow5
BronchialEpithelialCells5
CD105+_Endothelial5.1
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid6.4
CD34+6.5
CD4+_Tcells5.55
CD56+_NKCells5.95
CD71+_EarlyErythroid4.7
CD8+_Tcells4.85
CardiacMyocytes6.4
Caudatenucleus4.65
Cerebellum72.1
CerebellumPeduncles149.35
CiliaryGanglion4.8
CingulateCortex7.6
Colorectaladenocarcinoma5.15
DorsalRootGanglion4.3
FetalThyroid5
Fetalbrain5.25
Fetalliver4.6
Fetallung5.1
GlobusPallidus11.55
Heart7.05
Hypothalamus7.35
Kidney4.45
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4
Liver6.8
Lung5.65
Lymphnode4.35
Lymphoma_burkitts(Daudi)6.5
Lymphoma_burkitts(Raji)6.95
MedullaOblongata20.7
OccipitalLobe11.05
OlfactoryBulb4.05
Ovary4
Pancreas5.9
PancreaticIslet6.35
ParietalLobe7.65
Pituitary14.55
Placenta5.2
Pons6.4
PrefrontalCortex98.2
Prostate6.1
Salivarygland25.15
SkeletalMuscle6
Skin4.2
SmoothMuscle5.8
Spinalcord5.45
SubthalamicNucleus13.9
SuperiorCervicalGanglion6.4
TemporalLobe11.3
Testis4.4
TestisGermCell4.2
TestisIntersitial4.35
TestisLeydigCell5.1
TestisSeminiferousTubule4.4
Thalamus5.25
Thymus3.95
Thyroid8.9
Tongue5.2
Tonsil5.05
Trachea9.2
TrigeminalGanglion5.65
Uterus112.35
UterusCorpus6.05
WholeBlood5.6
Wholebrain13.35
colon5.55
pineal_day6.34
pineal_night6.16
retina13.625
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_139_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.6 ± 0.59
Basal Forebrain7.29 ± 0.32
Basal Part of Pons5.85 ± 0.58
Cerebellar Cortex8.59 ± 0.42
Cerebellar Nuclei5.27 ± 0.87
Claustrum8.45 ± 0.4
Epithalamus7.5 ± 0.94
Frontal Lobe7.28 ± 1
Globus Pallidus4.55 ± 1.17
Hypothalamus8.13 ± 0.91
Insula7.11 ± 0.59
Limbic Lobe7.2 ± 1.55
Mesencephalon7.95 ± 1.53
Myelencephalon7.36 ± 1.12
Occipital Lobe8.41 ± 0.44
Parietal Lobe8.03 ± 0.67
Pontine Tegmentum7.09 ± 0.84
Striatum5.04 ± 0.98
Subthalamus5.97 ± 0.72
Temporal Lobe7.58 ± 0.79
Thalamus7.05 ± 0.59
White Matter5.92 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cadps2CBCerebellum77.05
88.11
Cadps2CTXCerebral cortex67.39
69.97
Cadps2HIPHippocampal region28.43
54.68
Cadps2HPFHippocampal formation32.18
55.35
Cadps2HYHypothalamus24.36
25.44
Cadps2LSXLateral septal complex15.17
14.23
Cadps2MBMidbrain13.09
18
Cadps2MYMedulla11.26
13.48
Cadps2OLFOlfactory bulb39.66
41.23
Cadps2PPons9.13
11.3
Cadps2PALPallidum20.23
24.82
Cadps2RHPRetrohippocampal region39.6
57.18
Cadps2sAMYStriatum-like amygdalar nuclei38.05
39.19
Cadps2STRStriatum8.2
8.64
Cadps2STRdStriatum dorsal region2.74
3.27
Cadps2STRvStriatum ventral region4.62
4.76
Cadps2THThalamus7.39
12.04
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026211 24 251 274 KLEHQLLYNACQLDNADEQAAQIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018