AutismKB 2.0

Annotation Detail for ZFYVE9


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Basic Information Top
Gene Symbol:ZFYVE9 ( MADHIP,NSP,SARA,SMADIP )
Gene Full Name: zinc finger, FYVE domain containing 9
Band: 1p32.3
Quick LinksEntrez ID:9372; OMIM: 603755; Uniprot ID:ZFYV9_HUMAN; ENSEMBL ID: ENSG00000157077; HGNC ID: 6775
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal59 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate7 / 18934536
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204893_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.1
Adipocyte4.75
AdrenalCortex4.4
Adrenalgland3.6
Amygdala5.25
Appendix4.25
AtrioventricularNode3.15
BDCA4+_DentriticCells4.45
Bonemarrow4.1
BronchialEpithelialCells4.2
CD105+_Endothelial4.25
CD14+_Monocytes4.5
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.35
CD34+5.35
CD4+_Tcells4.55
CD56+_NKCells5
CD71+_EarlyErythroid3.9
CD8+_Tcells4
CardiacMyocytes5.5
Caudatenucleus4.15
Cerebellum4.65
CerebellumPeduncles5.2
CiliaryGanglion2.95
CingulateCortex10
Colorectaladenocarcinoma4.25
DorsalRootGanglion3.15
FetalThyroid4.25
Fetalbrain5.05
Fetalliver3.65
Fetallung3.65
GlobusPallidus3.75
Heart5.4
Hypothalamus5.7
Kidney5.65
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.4
Liver5.8
Lung4.75
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.8
MedullaOblongata6.55
OccipitalLobe3.9
OlfactoryBulb3.35
Ovary2.8
Pancreas3.35
PancreaticIslet4.55
ParietalLobe5.15
Pituitary5.35
Placenta4.35
Pons4.05
PrefrontalCortex5.55
Prostate5.05
Salivarygland3.3
SkeletalMuscle4.75
Skin3.2
SmoothMuscle5
Spinalcord4.75
SubthalamicNucleus3.9
SuperiorCervicalGanglion4.7
TemporalLobe5.95
Testis3.75
TestisGermCell3.65
TestisIntersitial3.55
TestisLeydigCell4.2
TestisSeminiferousTubule3.6
Thalamus4.3
Thymus3.4
Thyroid6
Tongue4.05
Tonsil4.1
Trachea3.6
TrigeminalGanglion4.2
Uterus3.55
UterusCorpus3.75
WholeBlood4.6
Wholebrain4.65
colon4.25
pineal_day5.28
pineal_night5.18
retina5.2
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6632_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.22 ± 0.38
Basal Forebrain6.11 ± 0.16
Basal Part of Pons6.37 ± 0.29
Cerebellar Cortex6.36 ± 0.14
Cerebellar Nuclei6.06 ± 0.29
Claustrum6.05 ± 0.39
Epithalamus5.78 ± 0.54
Frontal Lobe5.99 ± 0.38
Globus Pallidus5.47 ± 0.2
Hypothalamus5.96 ± 0.43
Insula5.94 ± 0.22
Limbic Lobe5.97 ± 0.32
Mesencephalon5.93 ± 0.37
Myelencephalon5.92 ± 0.38
Occipital Lobe6.09 ± 0.3
Parietal Lobe6.17 ± 0.34
Pontine Tegmentum5.99 ± 0.33
Striatum5.63 ± 0.32
Subthalamus6.33 ± 0.28
Temporal Lobe6.02 ± 0.31
Thalamus5.83 ± 0.43
White Matter5.08 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfyve9CBCerebellum23.8
41.38
Zfyve9CTXCerebral cortex31.45
25.31
Zfyve9HIPHippocampal region16.66
18.41
Zfyve9HPFHippocampal formation19.91
19.57
Zfyve9HYHypothalamus11.16
9.92
Zfyve9LSXLateral septal complex2.44
2.26
Zfyve9MBMidbrain23.86
26.42
Zfyve9MYMedulla38.46
55.93
Zfyve9OLFOlfactory bulb16.27
12.91
Zfyve9PPons32.08
44.02
Zfyve9PALPallidum18.03
20.07
Zfyve9RHPRetrohippocampal region26.54
22.2
Zfyve9sAMYStriatum-like amygdalar nuclei8.31
6.35
Zfyve9STRStriatum7.65
5.82
Zfyve9STRdStriatum dorsal region8.28
6.26
Zfyve9STRvStriatum ventral region7.61
5.59
Zfyve9THThalamus25.07
24.9
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00506445 23 225 247 SVNHLCPTSSDSLASVCSPSQLK Peptide Atlas
ZFYV9_HUMAN_212 9 212 220 QMDPLNRPK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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