AutismKB 2.0

Annotation Detail for TM9SF2


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Basic Information Top
Gene Symbol:TM9SF2 ( FLJ26287,MGC117391,P76 )
Gene Full Name: transmembrane 9 superfamily member 2
Band: 13q32.3
Quick LinksEntrez ID:9375; OMIM: 604678; Uniprot ID:TM9S2_HUMAN; ENSEMBL ID: ENSG00000125304; HGNC ID: 11865
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst2 / 6231932
fetus66 / 564012117
neonate11 / 31097353
infant0 / 236200 
juvenile13 / 55556233
adult293 / 1939121151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor14 / 127941094
bladder carcinoma6 / 17475343
breast (mammary gland) tumor30 / 94178318
cervical tumor5 / 34366145
chondrosarcoma5 / 8282360
colorectal tumor16 / 114246140
esophageal tumor10 / 17290578
gastrointestinal tumor14 / 119369117
germ cell tumor26 / 26384598
glioma14 / 106883130
head and neck tumor58 / 136302425
kidney tumor11 / 68959159
leukemia15 / 95842156
liver tumor33 / 96359342
lung tumor5 / 10312748
lymphoma3 / 7175541
non-neoplasia14 / 97250143
normal510 / 3360307151
ovarian tumor8 / 76682104
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer19 / 102680185
retinoblastoma3 / 4635664
skin tumor12 / 12494996
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor20 / 90257221
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland16 / 33197481
ascites2 / 4001549
bladder15 / 29757504
blood24 / 123478194
bone10 / 71655139
bone marrow13 / 48801266
brain183 / 1100989166
cervix5 / 48171103
connective tissue16 / 149255107
ear4 / 16212246
embryonic tissue25 / 215722115
esophagus10 / 20209494
eye13 / 21105461
heart7 / 8962678
intestine40 / 234472170
kidney29 / 211777136
larynx2 / 2414582
liver55 / 207743264
lung39 / 336974115
lymph2 / 4427045
lymph node9 / 9161098
mammary gland35 / 153271228
mouth21 / 67052313
muscle20 / 107715185
nerve1 / 1576863
ovary10 / 10205197
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx35 / 41328846
pituitary gland4 / 16585241
placenta46 / 280825163
prostate31 / 189345163
salivary gland1 / 2015549
skin24 / 210574113
spleen7 / 53952129
stomach16 / 96619165
testis77 / 330442233
thymus25 / 81131308
thyroid6 / 47473126
tonsil0 / 169990 
trachea14 / 52413267
umbilical cord0 / 136800 
uterus33 / 232878141
vascular21 / 51780405
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201078_at
Cell line Expression level Expression bar
721_B_lymphoblasts437.95
Adipocyte309.35
AdrenalCortex35.75
Adrenalgland136.8
Amygdala293.1
Appendix47.95
AtrioventricularNode75.95
BDCA4+_DentriticCells1158.1
Bonemarrow222.3
BronchialEpithelialCells436.9
CD105+_Endothelial117.6
CD14+_Monocytes591.5
CD19+_BCells(neg._sel.)168.5
CD33+_Myeloid712.55
CD34+310.75
CD4+_Tcells187.95
CD56+_NKCells284.5
CD71+_EarlyErythroid143.95
CD8+_Tcells239.55
CardiacMyocytes226.7
Caudatenucleus110.25
Cerebellum73.15
CerebellumPeduncles103.25
CiliaryGanglion53.15
CingulateCortex103.95
Colorectaladenocarcinoma372.8
DorsalRootGanglion85.05
FetalThyroid168.5
Fetalbrain132.4
Fetalliver318.55
Fetallung259.3
GlobusPallidus53.85
Heart29.8
Hypothalamus259.35
Kidney159.95
Leukemia_chronicMyelogenousK-562159.2
Leukemia_promyelocytic-HL-6054.4
Leukemialymphoblastic(MOLT-4)98.5
Liver111.8
Lung136.8
Lymphnode206.55
Lymphoma_burkitts(Daudi)152.45
Lymphoma_burkitts(Raji)24.25
MedullaOblongata79.15
OccipitalLobe134.3
OlfactoryBulb132.2
Ovary55.8
Pancreas682.2
PancreaticIslet324.7
ParietalLobe95.8
Pituitary294.2
Placenta1183.35
Pons37.05
PrefrontalCortex149.1
Prostate472.45
Salivarygland289.4
SkeletalMuscle16.5
Skin46.05
SmoothMuscle310.8
Spinalcord145.3
SubthalamicNucleus72.15
SuperiorCervicalGanglion32.45
TemporalLobe33.35
Testis249.75
TestisGermCell289.6
TestisIntersitial343.5
TestisLeydigCell239
TestisSeminiferousTubule150.5
Thalamus153.75
Thymus102.2
Thyroid624.4
Tongue46.8
Tonsil168.45
Trachea388
TrigeminalGanglion72.05
Uterus210.7
UterusCorpus75.3
WholeBlood643.3
Wholebrain227.05
colon684.15
pineal_day312.88
pineal_night308.24
retina446.55
small_intestine892.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P210399
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.04 ± 0.76
Basal Forebrain6.39 ± 0.4
Basal Part of Pons7.06 ± 0.53
Cerebellar Cortex7.03 ± 0.22
Cerebellar Nuclei6.7 ± 0.61
Claustrum6.06 ± 0.68
Epithalamus7.21 ± 0.4
Frontal Lobe6.81 ± 0.43
Globus Pallidus5.55 ± 0.39
Hypothalamus7.02 ± 0.45
Insula6.74 ± 0.42
Limbic Lobe6.21 ± 0.77
Mesencephalon6.41 ± 0.51
Myelencephalon6.49 ± 0.68
Occipital Lobe6.03 ± 0.68
Parietal Lobe6.53 ± 0.64
Pontine Tegmentum6.47 ± 0.61
Striatum5.74 ± 0.62
Subthalamus6.52 ± 1.21
Temporal Lobe6.69 ± 0.5
Thalamus6.49 ± 0.52
White Matter6.05 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tm9sf2CBCerebellum29.9
91.77
Tm9sf2CTXCerebral cortex100
100
Tm9sf2HIPHippocampal region100
100
Tm9sf2HPFHippocampal formation100
100
Tm9sf2HYHypothalamus52.81
56.12
Tm9sf2LSXLateral septal complex46.73
42.39
Tm9sf2MBMidbrain58.23
65.69
Tm9sf2MYMedulla78.1
100
Tm9sf2OLFOlfactory bulb86.71
100
Tm9sf2PPons56.62
74.2
Tm9sf2PALPallidum71.67
85.45
Tm9sf2RHPRetrohippocampal region100
100
Tm9sf2sAMYStriatum-like amygdalar nuclei100
100
Tm9sf2STRStriatum85.7
82.1
Tm9sf2STRdStriatum dorsal region81.68
75.43
Tm9sf2STRvStriatum ventral region98.08
90.51
Tm9sf2THThalamus66.42
70.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000293 33 58 90 AEIELFVNRLDSVESVLPYEYTAFDFCQASEGK Peptide Atlas
TM9S2_HUMAN_92 13 92 104 PSENLGQVLFGER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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