Annotation Detail for NRXN1
Basic Information Top
Gene Symbol: | NRXN1 ( DKFZp313P2036,FLJ35941,Hs.22998,KIAA0578,PTHSL2 ) |
---|---|
Gene Full Name: | neurexin 1 |
Band: | 2p16.3 |
Quick Links | Entrez ID:9378; OMIM: 600565; Uniprot ID:NRX1A_HUMAN; ENSEMBL ID: ENSG00000179915; HGNC ID: 8008 |
Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.637685
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
embryoid body | 1 / 70761 | 14 | |
blastocyst | 0 / 62319 | 0 | |
fetus | 49 / 564012 | 86 | |
neonate | 0 / 31097 | 0 | |
infant | 1 / 23620 | 42 | |
juvenile | 2 / 55556 | 35 | |
adult | 38 / 1939121 | 19 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adrenal tumor | 0 / 12794 | 0 | |
bladder carcinoma | 0 / 17475 | 0 | |
breast (mammary gland) tumor | 0 / 94178 | 0 | |
cervical tumor | 0 / 34366 | 0 | |
chondrosarcoma | 0 / 82823 | 0 | |
colorectal tumor | 2 / 114246 | 17 | |
esophageal tumor | 0 / 17290 | 0 | |
gastrointestinal tumor | 0 / 119369 | 0 | |
germ cell tumor | 21 / 263845 | 79 | |
glioma | 7 / 106883 | 65 | |
head and neck tumor | 0 / 136302 | 0 | |
kidney tumor | 2 / 68959 | 29 | |
leukemia | 0 / 95842 | 0 | |
liver tumor | 0 / 96359 | 0 | |
lung tumor | 3 / 103127 | 29 | |
lymphoma | 0 / 71755 | 0 | |
non-neoplasia | 4 / 97250 | 41 | |
normal | 165 / 3360307 | 49 | |
ovarian tumor | 0 / 76682 | 0 | |
pancreatic tumor | 4 / 104616 | 38 | |
primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
prostate cancer | 0 / 102680 | 0 | |
retinoblastoma | 0 / 46356 | 0 | |
skin tumor | 7 / 124949 | 56 | |
soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
uterine tumor | 0 / 90257 | 0 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adipose tissue | 0 / 13106 | 0 | |
adrenal gland | 0 / 33197 | 0 | |
ascites | 0 / 40015 | 0 | |
bladder | 0 / 29757 | 0 | |
blood | 0 / 123478 | 0 | |
bone | 0 / 71655 | 0 | |
bone marrow | 0 / 48801 | 0 | |
brain | 169 / 1100989 | 153 | |
cervix | 0 / 48171 | 0 | |
connective tissue | 1 / 149255 | 6 | |
ear | 3 / 16212 | 185 | |
embryonic tissue | 3 / 215722 | 13 | |
esophagus | 0 / 20209 | 0 | |
eye | 2 / 211054 | 9 | |
heart | 0 / 89626 | 0 | |
intestine | 3 / 234472 | 12 | |
kidney | 3 / 211777 | 14 | |
larynx | 0 / 24145 | 0 | |
liver | 1 / 207743 | 4 | |
lung | 4 / 336974 | 11 | |
lymph | 0 / 44270 | 0 | |
lymph node | 0 / 91610 | 0 | |
mammary gland | 0 / 153271 | 0 | |
mouth | 0 / 67052 | 0 | |
muscle | 5 / 107715 | 46 | |
nerve | 2 / 15768 | 126 | |
ovary | 0 / 102051 | 0 | |
pancreas | 8 / 214812 | 37 | |
parathyroid | 0 / 20539 | 0 | |
pharynx | 1 / 41328 | 24 | |
pituitary gland | 1 / 16585 | 60 | |
placenta | 1 / 280825 | 3 | |
prostate | 0 / 189345 | 0 | |
salivary gland | 0 / 20155 | 0 | |
skin | 7 / 210574 | 33 | |
spleen | 0 / 53952 | 0 | |
stomach | 0 / 96619 | 0 | |
testis | 12 / 330442 | 36 | |
thymus | 0 / 81131 | 0 | |
thyroid | 0 / 47473 | 0 | |
tonsil | 0 / 16999 | 0 | |
trachea | 1 / 52413 | 19 | |
umbilical cord | 0 / 13680 | 0 | |
uterus | 2 / 232878 | 8 | |
vascular | 1 / 51780 | 19 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209915_s_at
Cell line | Expression level | Expression bar |
---|---|---|
721_B_lymphoblasts | 7.45 | |
Adipocyte | 6.75 | |
AdrenalCortex | 9.85 | |
Adrenalgland | 6.55 | |
Amygdala | 225.9 | |
Appendix | 33.05 | |
AtrioventricularNode | 8.55 | |
BDCA4+_DentriticCells | 6.25 | |
Bonemarrow | 7.65 | |
BronchialEpithelialCells | 6.05 | |
CD105+_Endothelial | 6.4 | |
CD14+_Monocytes | 6.8 | |
CD19+_BCells(neg._sel.) | 7.05 | |
CD33+_Myeloid | 7.9 | |
CD34+ | 6.9 | |
CD4+_Tcells | 6.3 | |
CD56+_NKCells | 6.8 | |
CD71+_EarlyErythroid | 6.2 | |
CD8+_Tcells | 5.65 | |
CardiacMyocytes | 8.3 | |
Caudatenucleus | 25.55 | |
Cerebellum | 34.3 | |
CerebellumPeduncles | 53.4 | |
CiliaryGanglion | 13.45 | |
CingulateCortex | 71.6 | |
Colorectaladenocarcinoma | 6.7 | |
DorsalRootGanglion | 10.55 | |
FetalThyroid | 6.9 | |
Fetalbrain | 345.55 | |
Fetalliver | 6.05 | |
Fetallung | 5.4 | |
GlobusPallidus | 115.35 | |
Heart | 9.2 | |
Hypothalamus | 70.15 | |
Kidney | 6.85 | |
Leukemia_chronicMyelogenousK-562 | 6.15 | |
Leukemia_promyelocytic-HL-60 | 6.25 | |
Leukemialymphoblastic(MOLT-4) | 5.55 | |
Liver | 10.95 | |
Lung | 7.25 | |
Lymphnode | 5.75 | |
Lymphoma_burkitts(Daudi) | 9.3 | |
Lymphoma_burkitts(Raji) | 9.15 | |
MedullaOblongata | 91.15 | |
OccipitalLobe | 150.05 | |
OlfactoryBulb | 18.6 | |
Ovary | 5.5 | |
Pancreas | 5.65 | |
PancreaticIslet | 7.4 | |
ParietalLobe | 102.45 | |
Pituitary | 9.9 | |
Placenta | 6.5 | |
Pons | 82.3 | |
PrefrontalCortex | 132 | |
Prostate | 7.75 | |
Salivarygland | 6.15 | |
SkeletalMuscle | 10.5 | |
Skin | 9.05 | |
SmoothMuscle | 7.5 | |
Spinalcord | 8.6 | |
SubthalamicNucleus | 83.55 | |
SuperiorCervicalGanglion | 17.9 | |
TemporalLobe | 66.05 | |
Testis | 6.05 | |
TestisGermCell | 5.7 | |
TestisIntersitial | 5.8 | |
TestisLeydigCell | 7.55 | |
TestisSeminiferousTubule | 5.85 | |
Thalamus | 87.7 | |
Thymus | 4.95 | |
Thyroid | 8.1 | |
Tongue | 6.95 | |
Tonsil | 6.9 | |
Trachea | 5.9 | |
TrigeminalGanglion | 8.75 | |
Uterus | 5.25 | |
UterusCorpus | 8.05 | |
WholeBlood | 6.2 | |
Wholebrain | 60.2 | |
colon | 6.4 | |
pineal_day | 20.72 | |
pineal_night | 48.24 | |
retina | 8.05 | |
small_intestine | 6.2 |
Human Whole Brain Microarrayview in Allen Brain Atlas
- Probe name: CUST_484_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue | Expression(mean ± stddev) | Expression Bar |
---|---|---|
Amygdala | 9.97 ± 0.35 | |
Basal Forebrain | 9.38 ± 0.19 | |
Basal Part of Pons | 9.17 ± 0.21 | |
Cerebellar Cortex | 9.81 ± 0.18 | |
Cerebellar Nuclei | 8.77 ± 0.3 | |
Claustrum | 9.4 ± 0.44 | |
Epithalamus | 8.91 ± 0.59 | |
Frontal Lobe | 9.34 ± 0.44 | |
Globus Pallidus | 8.78 ± 0.17 | |
Hypothalamus | 9.24 ± 0.62 | |
Insula | 9.5 ± 0.35 | |
Limbic Lobe | 9.54 ± 0.38 | |
Mesencephalon | 9.39 ± 0.37 | |
Myelencephalon | 9.38 ± 0.42 | |
Occipital Lobe | 9.49 ± 0.41 | |
Parietal Lobe | 9.43 ± 0.4 | |
Pontine Tegmentum | 9.4 ± 0.51 | |
Striatum | 8.7 ± 0.31 | |
Subthalamus | 9.3 ± 0.17 | |
Temporal Lobe | 9.52 ± 0.32 | |
Thalamus | 9.65 ± 0.36 | |
White Matter | 8.04 ± 0.22 |
Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
---|---|---|---|---|
Nrxn1 | CB | Cerebellum | 100 | |
100 | ||||
Nrxn1 | CTX | Cerebral cortex | 100 | |
100 | ||||
Nrxn1 | HIP | Hippocampal region | 89.27 | |
100 | ||||
Nrxn1 | HPF | Hippocampal formation | 100 | |
100 | ||||
Nrxn1 | HY | Hypothalamus | 100 | |
100 | ||||
Nrxn1 | LSX | Lateral septal complex | 100 | |
100 | ||||
Nrxn1 | MB | Midbrain | 100 | |
100 | ||||
Nrxn1 | MY | Medulla | 100 | |
100 | ||||
Nrxn1 | OLF | Olfactory bulb | 100 | |
100 | ||||
Nrxn1 | P | Pons | 100 | |
100 | ||||
Nrxn1 | PAL | Pallidum | 100 | |
100 | ||||
Nrxn1 | RHP | Retrohippocampal region | 100 | |
100 | ||||
Nrxn1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
100 | ||||
Nrxn1 | STR | Striatum | 75.34 | |
73.89 | ||||
Nrxn1 | STRd | Striatum dorsal region | 56.18 | |
53.71 | ||||
Nrxn1 | STRv | Striatum ventral region | 86.08 | |
77.96 | ||||
Nrxn1 | TH | Thalamus | 100 | |
100 |