Annotation Detail for COG1
Basic Information Top
| Gene Symbol: | COG1 ( CDG2G,DKFZp762L1710,KIAA1381,LDLB ) |
|---|---|
| Gene Full Name: | component of oligomeric golgi complex 1 |
| Band: | 17q25.1 |
| Quick Links | Entrez ID:9382; OMIM: 606973; Uniprot ID:COG1_HUMAN; ENSEMBL ID: ENSG00000166685; HGNC ID: 6545 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.283109
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 27 / 564012 | 47 | |
| neonate | 1 / 31097 | 32 | |
| infant | 2 / 23620 | 84 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 122 / 1939121 | 62 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 10 / 94178 | 106 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 10 / 119369 | 83 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 14 / 106883 | 130 | |
| head and neck tumor | 11 / 136302 | 80 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 11 / 96359 | 114 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 8 / 97250 | 82 | |
| normal | 183 / 3360307 | 54 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 1 / 104616 | 9 |  |
| primitive neuroectodermal tumor of the CNS | 6 / 125680 | 47 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 4 / 46356 | 86 | |
| skin tumor | 14 / 124949 | 112 | |
| soft tissue/muscle tissue tumor | 12 / 125191 | 95 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 5 / 123478 | 40 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 69 / 1100989 | 62 | |
| cervix | 5 / 48171 | 103 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 14 / 211054 | 66 | |
| heart | 4 / 89626 | 44 | |
| intestine | 10 / 234472 | 42 | |
| kidney | 13 / 211777 | 61 | |
| larynx | 1 / 24145 | 41 | |
| liver | 13 / 207743 | 62 | |
| lung | 24 / 336974 | 71 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 11 / 153271 | 71 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 12 / 107715 | 111 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 4 / 16585 | 241 |  |
| placenta | 13 / 280825 | 46 | |
| prostate | 10 / 189345 | 52 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 19 / 210574 | 90 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 9 / 96619 | 93 | |
| testis | 18 / 330442 | 54 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 15 / 232878 | 64 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_11758_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.75 ± 0.25 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.43 ± 0.18 | |
| Basal Part of Pons | 8.65 ± 0.26 | |
| Cerebellar Cortex | 8.43 ± 0.25 | |
| Cerebellar Nuclei | 8.06 ± 0.35 | |
| Claustrum | 9.09 ± 0.25 | |
| Epithalamus | 8.3 ± 0.3 | |
| Frontal Lobe | 8.58 ± 0.31 | |
| Globus Pallidus | 7.36 ± 0.3 | |
| Hypothalamus | 8.43 ± 0.34 | |
| Insula | 8.68 ± 0.23 | |
| Limbic Lobe | 8.77 ± 0.35 | |
| Mesencephalon | 8.26 ± 0.3 | |
| Myelencephalon | 8.42 ± 0.39 | |
| Occipital Lobe | 8.12 ± 0.38 | |
| Parietal Lobe | 8.42 ± 0.36 | |
| Pontine Tegmentum | 8.46 ± 0.44 | |
| Striatum | 8.43 ± 0.48 | |
| Subthalamus | 8.26 ± 0.08 | |
| Temporal Lobe | 8.72 ± 0.37 | |
| Thalamus | 8.12 ± 0.24 | |
| White Matter | 7.72 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cog1 | CB | Cerebellum | 74.16 | |
| 100 | | |||
| Cog1 | CTX | Cerebral cortex | 100 | |
| 89.05 | | |||
| Cog1 | HIP | Hippocampal region | 81.66 | |
| 100 | | |||
| Cog1 | HPF | Hippocampal formation | 95.31 | |
| 100 | | |||
| Cog1 | HY | Hypothalamus | 80.21 | |
| 64.28 | | |||
| Cog1 | LSX | Lateral septal complex | 86.01 | |
| 64.16 | | |||
| Cog1 | MB | Midbrain | 68.15 | |
| 62.76 | | |||
| Cog1 | MY | Medulla | 77.58 | |
| 88.45 | | |||
| Cog1 | OLF | Olfactory bulb | 100 | |
| 90.66 | | |||
| Cog1 | P | Pons | 69.83 | |
| 76.06 | | |||
| Cog1 | PAL | Pallidum | 66.61 | |
| 58.97 | | |||
| Cog1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Cog1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 76.82 | | |||
| Cog1 | STR | Striatum | 88.54 | |
| 64.72 | | |||
| Cog1 | STRd | Striatum dorsal region | 89.88 | |
| 66.09 | | |||
| Cog1 | STRv | Striatum ventral region | 84.71 | |
| 59.09 | | |||
| Cog1 | TH | Thalamus | 66.19 | |
| 53.78 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| COG1_HUMAN_179 | 9 | 179 | 187 | QVAAASHFR | PRIDE |
| COG1_HUMAN_2 | 11 | 2 | 12 | ATAATSPALKR | PRIDE |
| COG1_HUMAN_225 | 10 | 225 | 234 | QALTDFLLAR | PRIDE |