AutismKB 2.0

Annotation Detail for FOXP2


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Basic Information Top
Gene Symbol:FOXP2 ( CAGH44,DKFZp686H1726,SPCH1,TNRC10 )
Gene Full Name: forkhead box P2
Band: 7q31.1
Quick LinksEntrez ID:93986; OMIM: 605317; Uniprot ID:FOXP2_HUMAN; ENSEMBL ID: ENSG00000128573; HGNC ID: 13875
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal59 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain14 / 110098912
cervix1 / 4817120
connective tissue0 / 1492550 
ear8 / 16212493
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver6 / 20774328
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth5 / 6705274
muscle2 / 10771518
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P921683
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.22 ± 1.05
Basal Forebrain4.82 ± 0.75
Basal Part of Pons4.07 ± 0.76
Cerebellar Cortex3.48 ± 0.68
Cerebellar Nuclei4 ± 0.57
Claustrum3.43 ± 1.01
Epithalamus5.13 ± 0.61
Frontal Lobe4.15 ± 0.88
Globus Pallidus4.49 ± 0.65
Hypothalamus4.63 ± 0.6
Insula4.52 ± 0.56
Limbic Lobe3.86 ± 0.74
Mesencephalon4.67 ± 0.7
Myelencephalon4.43 ± 1.03
Occipital Lobe4.97 ± 0.92
Parietal Lobe4.75 ± 0.76
Pontine Tegmentum4.48 ± 1.04
Striatum4.96 ± 0.75
Subthalamus5.7 ± 0.2
Temporal Lobe4.85 ± 0.76
Thalamus5.35 ± 0.77
White Matter3.68 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Foxp2CBCerebellum22.27
30.04
Foxp2CTXCerebral cortex18.73
14.81
Foxp2HIPHippocampal region4.57
4.97
Foxp2HPFHippocampal formation6.02
5.97
Foxp2HYHypothalamus13.91
12.82
Foxp2LSXLateral septal complex38.36
33.11
Foxp2MBMidbrain37.31
35.51
Foxp2MYMedulla8.04
10.93
Foxp2OLFOlfactory bulb20.28
18.48
Foxp2PPons9.91
10.63
Foxp2PALPallidum24.48
27.8
Foxp2RHPRetrohippocampal region8.04
7.03
Foxp2sAMYStriatum-like amygdalar nuclei30.08
27.08
Foxp2STRStriatum68.86
59.68
Foxp2STRdStriatum dorsal region71.78
58.08
Foxp2STRvStriatum ventral region88.13
84.03
Foxp2THThalamus40.22
39.9
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018