AutismKB 2.0

Annotation Detail for PIGS


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Basic Information Top
Gene Symbol:PIGS ( DKFZp686K20216,FLJ45226 )
Gene Full Name: phosphatidylinositol glycan anchor biosynthesis, class S
Band: 17q11.2
Quick LinksEntrez ID:94005; OMIM: 610271; Uniprot ID:PIGS_HUMAN; ENSEMBL ID: ENSG00000087111; HGNC ID: 14937
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus38 / 56401267
neonate2 / 3109764
infant1 / 2362042
juvenile10 / 55556179
adult121 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor4 / 34366116
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor5 / 17290289
gastrointestinal tumor12 / 119369100
germ cell tumor36 / 263845136
glioma12 / 106883112
head and neck tumor19 / 136302139
kidney tumor8 / 68959116
leukemia7 / 9584273
liver tumor10 / 96359103
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal247 / 336030773
ovarian tumor6 / 7668278
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer12 / 102680116
retinoblastoma6 / 46356129
skin tumor3 / 12494924
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites7 / 40015174
bladder1 / 2975733
blood10 / 12347880
bone7 / 7165597
bone marrow4 / 4880181
brain101 / 110098991
cervix4 / 4817183
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus5 / 20209247
eye19 / 21105490
heart7 / 8962678
intestine12 / 23447251
kidney27 / 211777127
larynx4 / 24145165
liver11 / 20774352
lung28 / 33697483
lymph0 / 442700 
lymph node0 / 916100 
mammary gland14 / 15327191
mouth16 / 67052238
muscle5 / 10771546
nerve1 / 1576863
ovary8 / 10205178
pancreas21 / 21481297
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate20 / 189345105
salivary gland1 / 2015549
skin11 / 21057452
spleen7 / 53952129
stomach5 / 9661951
testis33 / 33044299
thymus8 / 8113198
thyroid6 / 47473126
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus13 / 23287855
vascular5 / 5178096
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8452_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.31 ± 0.64
Basal Forebrain3.18 ± 0.63
Basal Part of Pons3.85 ± 0.36
Cerebellar Cortex3.93 ± 0.3
Cerebellar Nuclei3.43 ± 0.37
Claustrum3.61 ± 0.52
Epithalamus3.26 ± 0.47
Frontal Lobe3.68 ± 0.49
Globus Pallidus3.31 ± 0.59
Hypothalamus3.67 ± 0.4
Insula3.36 ± 0.61
Limbic Lobe3.78 ± 0.47
Mesencephalon3.48 ± 0.54
Myelencephalon3.54 ± 0.51
Occipital Lobe3.52 ± 0.52
Parietal Lobe3.59 ± 0.42
Pontine Tegmentum3.57 ± 0.61
Striatum3.2 ± 0.53
Subthalamus3.32 ± 0.3
Temporal Lobe3.57 ± 0.49
Thalamus3.59 ± 0.45
White Matter3.79 ± 0.41
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000123 14 2 15 AAAGAAATHLEVAR Peptide Atlas
PIGS_HUMAN_1 14 1 14 AAAGAAATHLEVAR PRIDE
PIGS_HUMAN_384 10 384 393 VMEVFLAQLR PRIDE
PIGS_HUMAN_60 11 60 70 LMVPVTVVFTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018