AutismKB 2.0

Annotation Detail for ZRANB2


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Basic Information Top
Gene Symbol:ZRANB2 ( DKFZp686J1831,DKFZp686N09117,FLJ41119,ZIS,ZIS1,ZIS2,ZNF265 )
Gene Full Name: zinc finger, RAN-binding domain containing 2
Band: 1p31.1
Quick LinksEntrez ID:9406; OMIM: 604347; Uniprot ID:ZRAB2_HUMAN; ENSEMBL ID: ENSG00000132485; HGNC ID: 13058
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst12 / 62319192
fetus72 / 564012127
neonate1 / 3109732
infant3 / 23620127
juvenile8 / 55556143
adult214 / 1939121110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor16 / 119369134
germ cell tumor45 / 263845170
glioma3 / 10688328
head and neck tumor16 / 136302117
kidney tumor10 / 68959145
leukemia8 / 9584283
liver tumor13 / 96359134
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal578 / 3360307172
ovarian tumor5 / 7668265
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor5 / 12494940
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland9 / 33197271
ascites6 / 40015149
bladder2 / 2975767
blood12 / 12347897
bone5 / 7165569
bone marrow6 / 48801122
brain170 / 1100989154
cervix2 / 4817141
connective tissue10 / 14925566
ear4 / 16212246
embryonic tissue32 / 215722148
esophagus1 / 2020949
eye20 / 21105494
heart8 / 8962689
intestine13 / 23447255
kidney16 / 21177775
larynx3 / 24145124
liver175 / 207743842
lung20 / 33697459
lymph1 / 4427022
lymph node19 / 91610207
mammary gland4 / 15327126
mouth7 / 67052104
muscle31 / 107715287
nerve3 / 15768190
ovary7 / 10205168
pancreas17 / 21481279
parathyroid2 / 2053997
pharynx3 / 4132872
pituitary gland4 / 16585241
placenta28 / 28082599
prostate19 / 189345100
salivary gland1 / 2015549
skin9 / 21057442
spleen6 / 53952111
stomach9 / 9661993
testis47 / 330442142
thymus19 / 81131234
thyroid8 / 47473168
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus41 / 232878176
vascular11 / 51780212
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P85521
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.26 ± 0.21
Basal Forebrain7.22 ± 0.2
Basal Part of Pons7.37 ± 0.25
Cerebellar Cortex7.43 ± 0.2
Cerebellar Nuclei7.16 ± 0.26
Claustrum6.97 ± 0.27
Epithalamus7.54 ± 0.29
Frontal Lobe7.26 ± 0.29
Globus Pallidus6.98 ± 0.23
Hypothalamus7.18 ± 0.23
Insula7.22 ± 0.35
Limbic Lobe7.25 ± 0.32
Mesencephalon7.12 ± 0.27
Myelencephalon7.2 ± 0.28
Occipital Lobe7.37 ± 0.28
Parietal Lobe7.28 ± 0.24
Pontine Tegmentum7.24 ± 0.26
Striatum7.15 ± 0.2
Subthalamus7.14 ± 0.19
Temporal Lobe7.26 ± 0.25
Thalamus7.19 ± 0.22
White Matter7.88 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zranb2CBCerebellum22.38
23.42
Zranb2CTXCerebral cortex37.01
28.36
Zranb2HIPHippocampal region32.41
39.47
Zranb2HPFHippocampal formation32.26
33.56
Zranb2HYHypothalamus15.46
12.39
Zranb2LSXLateral septal complex7.32
5.64
Zranb2MBMidbrain21.92
19.85
Zranb2MYMedulla32.94
33.16
Zranb2OLFOlfactory bulb44.3
37.59
Zranb2PPons30.13
29.02
Zranb2PALPallidum15.82
13.03
Zranb2RHPRetrohippocampal region32.43
25.99
Zranb2sAMYStriatum-like amygdalar nuclei19.53
13.24
Zranb2STRStriatum6.65
4.99
Zranb2STRdStriatum dorsal region3.96
3.17
Zranb2STRvStriatum ventral region8.67
6.25
Zranb2THThalamus25.93
20.98
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001025 8 20 27 CGNVNFAR Peptide Atlas
ZRAB2_HUMAN_2 6 2 7 STKNFR PRIDE
ZRAB2_HUMAN_208 9 208 216 SSHSRSSSR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018