AutismKB 2.0

Annotation Detail for SYTL3


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Basic Information Top
Gene Symbol:SYTL3 ( MGC105130,MGC118883,MGC118884,MGC118885,SLP3 )
Gene Full Name: synaptotagmin-like 3
Band: 6q25.3
Quick LinksEntrez ID:94120; OMIM: NA; Uniprot ID:SYTL3_HUMAN; ENSEMBL ID: ENSG00000164674; HGNC ID: 15587
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus7 / 56401212
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal46 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone2 / 7165527
bone marrow1 / 4880120
brain10 / 11009899
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye1 / 2110544
heart0 / 896260 
intestine5 / 23447221
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach1 / 9661910
testis1 / 3304423
thymus11 / 81131135
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P291826
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.13 ± 1.03
Basal Forebrain1.6 ± 0.19
Basal Part of Pons1.4 ± 0.69
Cerebellar Cortex1.46 ± 0.68
Cerebellar Nuclei2.03 ± 0.77
Claustrum2.39 ± 0.79
Epithalamus2.18 ± 1.07
Frontal Lobe1.64 ± 0.71
Globus Pallidus2.28 ± 0.45
Hypothalamus1.62 ± 0.71
Insula1.4 ± 0.69
Limbic Lobe1.59 ± 0.65
Mesencephalon1.83 ± 0.64
Myelencephalon1.76 ± 0.73
Occipital Lobe1.56 ± 0.51
Parietal Lobe1.78 ± 0.83
Pontine Tegmentum1.7 ± 0.7
Striatum1.95 ± 0.74
Subthalamus1.81 ± 0.69
Temporal Lobe1.61 ± 0.74
Thalamus1.74 ± 0.62
White Matter1.97 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sytl3CBCerebellum12.34
14.68
Sytl3CTXCerebral cortex0.97
0.79
Sytl3HIPHippocampal region1.7
0.82
Sytl3HPFHippocampal formation1.62
0.99
Sytl3HYHypothalamus0.74
0.51
Sytl3LSXLateral septal complex3.39
2.22
Sytl3MBMidbrain0.69
0.61
Sytl3MYMedulla4.5
3.21
Sytl3OLFOlfactory bulb2.5
2.07
Sytl3PPons2.5
2.07
Sytl3PALPallidum0.28
0.17
Sytl3RHPRetrohippocampal region1.19
1.07
Sytl3sAMYStriatum-like amygdalar nuclei1.26
0.75
Sytl3STRStriatum0.69
0.45
Sytl3STRdStriatum dorsal region0.11
0.12
Sytl3STRvStriatum ventral region1.21
0.67
Sytl3THThalamus4.88
3.02
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018