AutismKB 2.0

Annotation Detail for SYTL4


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Basic Information Top
Gene Symbol:SYTL4 ( DKFZp451P0116,FLJ40960,SLP4 )
Gene Full Name: synaptotagmin-like 4
Band: Xq22.1
Quick LinksEntrez ID:94121; OMIM: 300723; Uniprot ID:SYTL4_HUMAN; ENSEMBL ID: ENSG00000102362; HGNC ID: 15588
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus22 / 56401239
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal57 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma4 / 4635686
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone4 / 7165555
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus2 / 2020998
eye4 / 21105418
heart1 / 8962611
intestine1 / 2344724
kidney2 / 2117779
larynx1 / 2414541
liver3 / 20774314
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis4 / 33044212
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus30 / 232878128
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13157_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.2 ± 0.71
Basal Forebrain4.7 ± 0.7
Basal Part of Pons3.09 ± 0.61
Cerebellar Cortex3.24 ± 0.54
Cerebellar Nuclei3.68 ± 0.66
Claustrum3.73 ± 0.57
Epithalamus4.51 ± 0.5
Frontal Lobe3.79 ± 0.82
Globus Pallidus6.42 ± 0.7
Hypothalamus4.19 ± 0.72
Insula3.53 ± 0.79
Limbic Lobe3.83 ± 0.87
Mesencephalon4.33 ± 0.75
Myelencephalon4.03 ± 0.79
Occipital Lobe3.91 ± 0.92
Parietal Lobe3.68 ± 0.83
Pontine Tegmentum3.98 ± 0.76
Striatum4.67 ± 0.56
Subthalamus3.59 ± 0.6
Temporal Lobe3.74 ± 0.69
Thalamus4.01 ± 0.67
White Matter4.95 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sytl4CBCerebellum1.09
2.48
Sytl4CTXCerebral cortex0.58
0.78
Sytl4HIPHippocampal region0.42
0.67
Sytl4HPFHippocampal formation0.41
0.64
Sytl4HYHypothalamus0.95
1.04
Sytl4LSXLateral septal complex0.44
0.37
Sytl4MBMidbrain0.62
0.78
Sytl4MYMedulla0.63
0.79
Sytl4OLFOlfactory bulb1.67
1.76
Sytl4PPons4.67
7.99
Sytl4PALPallidum1.73
1.63
Sytl4RHPRetrohippocampal region0.39
0.54
Sytl4sAMYStriatum-like amygdalar nuclei0.86
0.64
Sytl4STRStriatum2.38
3.02
Sytl4STRdStriatum dorsal region3.63
4.84
Sytl4STRvStriatum ventral region0.31
0.26
Sytl4THThalamus0.51
0.96
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018