AutismKB 2.0

Annotation Detail for FAM189A2


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Basic Information Top
Gene Symbol:FAM189A2 ( C9orf61,MGC142243,MGC142245,RP11-548B3.1,X123 )
Gene Full Name: family with sequence similarity 189, member A2
Band: 9q21.12
Quick LinksEntrez ID:9413; OMIM: 607710; Uniprot ID:F1892_HUMAN; ENSEMBL ID: ENSG00000135063; HGNC ID: 24820
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal37 / 336030711
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine4 / 23447217
kidney2 / 2117779
larynx2 / 2414582
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213900_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte3.9
AdrenalCortex4.1
Adrenalgland3.3
Amygdala5.05
Appendix4.1
AtrioventricularNode3
BDCA4+_DentriticCells4.45
Bonemarrow3.9
BronchialEpithelialCells3.85
CD105+_Endothelial4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.15
CD34+5.05
CD4+_Tcells4.3
CD56+_NKCells4.75
CD71+_EarlyErythroid3.7
CD8+_Tcells3.8
CardiacMyocytes4.9
Caudatenucleus5.9
Cerebellum3.25
CerebellumPeduncles5.4
CiliaryGanglion3.15
CingulateCortex4.05
Colorectaladenocarcinoma4
DorsalRootGanglion3.1
FetalThyroid8.3
Fetalbrain3.95
Fetalliver3.4
Fetallung6.55
GlobusPallidus3.1
Heart5.3
Hypothalamus9.3
Kidney3.2
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.45
Leukemialymphoblastic(MOLT-4)3.3
Liver5.25
Lung31.1
Lymphnode3.4
Lymphoma_burkitts(Daudi)5
Lymphoma_burkitts(Raji)5.55
MedullaOblongata3.65
OccipitalLobe3.65
OlfactoryBulb4.6
Ovary2.65
Pancreas3.2
PancreaticIslet4.25
ParietalLobe4.2
Pituitary4.65
Placenta4.15
Pons4.5
PrefrontalCortex6.8
Prostate10.95
Salivarygland4.55
SkeletalMuscle9.75
Skin6
SmoothMuscle4.5
Spinalcord26.3
SubthalamicNucleus5
SuperiorCervicalGanglion4.8
TemporalLobe5.1
Testis3.4
TestisGermCell3.35
TestisIntersitial3.35
TestisLeydigCell3.9
TestisSeminiferousTubule3.4
Thalamus9.95
Thymus3.4
Thyroid190.15
Tongue3.9
Tonsil3.8
Trachea3.35
TrigeminalGanglion4.05
Uterus3.5
UterusCorpus3.65
WholeBlood4.35
Wholebrain3.45
colon3.95
pineal_day6.34
pineal_night5.6
retina24.975
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P422831
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.29 ± 0.36
Basal Forebrain7.63 ± 0.28
Basal Part of Pons6.76 ± 0.3
Cerebellar Cortex7.02 ± 0.31
Cerebellar Nuclei7.55 ± 0.76
Claustrum7.11 ± 0.43
Epithalamus8.78 ± 0.32
Frontal Lobe7.37 ± 0.5
Globus Pallidus9.5 ± 0.69
Hypothalamus7.81 ± 0.5
Insula7.39 ± 0.32
Limbic Lobe7.26 ± 0.77
Mesencephalon7.76 ± 0.55
Myelencephalon7.61 ± 0.62
Occipital Lobe7.49 ± 0.54
Parietal Lobe7.32 ± 0.57
Pontine Tegmentum7.76 ± 0.31
Striatum8.2 ± 0.56
Subthalamus7.37 ± 0.39
Temporal Lobe7.2 ± 0.42
Thalamus7.94 ± 0.39
White Matter8.15 ± 0.58
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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