AutismKB 2.0

Annotation Detail for NTN1


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Basic Information Top
Gene Symbol:NTN1 ( NTN1L )
Gene Full Name: netrin 1
Band: 17p13.1
Quick LinksEntrez ID:9423; OMIM: 601614; Uniprot ID:NET1_HUMAN; ENSEMBL ID: ENSG00000065320; HGNC ID: 8029
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus3 / 5640125
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal22 / 33603076
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye6 / 21105428
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary5 / 10205148
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208005_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte3.9
AdrenalCortex4.1
Adrenalgland3.4
Amygdala4.2
Appendix4.65
AtrioventricularNode3
BDCA4+_DentriticCells4.4
Bonemarrow3.95
BronchialEpithelialCells3.95
CD105+_Endothelial4.05
CD14+_Monocytes4.25
CD19+_BCells(neg._sel.)4.25
CD33+_Myeloid5.05
CD34+5.05
CD4+_Tcells4.3
CD56+_NKCells4.8
CD71+_EarlyErythroid3.7
CD8+_Tcells3.8
CardiacMyocytes5.05
Caudatenucleus3.6
Cerebellum3.2
CerebellumPeduncles4.5
CiliaryGanglion2.85
CingulateCortex4.05
Colorectaladenocarcinoma4
DorsalRootGanglion3
FetalThyroid3.9
Fetalbrain3.95
Fetalliver3.45
Fetallung3.35
GlobusPallidus2.9
Heart5.15
Hypothalamus4.3
Kidney3.3
Leukemia_chronicMyelogenousK-5623.6
Leukemia_promyelocytic-HL-603.5
Leukemialymphoblastic(MOLT-4)3.25
Liver5.3
Lung4.4
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.1
Lymphoma_burkitts(Raji)5.65
MedullaOblongata3.7
OccipitalLobe3.6
OlfactoryBulb3.15
Ovary2.6
Pancreas3.2
PancreaticIslet4.25
ParietalLobe4.25
Pituitary4.65
Placenta4.2
Pons3.8
PrefrontalCortex4.9
Prostate4.7
Salivarygland3.2
SkeletalMuscle4.75
Skin3.05
SmoothMuscle4.55
Spinalcord4.25
SubthalamicNucleus3.65
SuperiorCervicalGanglion4.45
TemporalLobe3.85
Testis3.4
TestisGermCell3.3
TestisIntersitial3.3
TestisLeydigCell3.95
TestisSeminiferousTubule3.4
Thalamus4
Thymus3.2
Thyroid5.05
Tongue3.9
Tonsil3.9
Trachea3.3
TrigeminalGanglion3.9
Uterus3.25
UterusCorpus3.6
WholeBlood4.35
Wholebrain3.45
colon4.05
pineal_day4.96
pineal_night4.84
retina4.825
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P234913
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.27 ± 0.75
Basal Forebrain11.98 ± 0.24
Basal Part of Pons12.33 ± 0.3
Cerebellar Cortex11.77 ± 0.53
Cerebellar Nuclei12.32 ± 0.24
Claustrum12.38 ± 0.44
Epithalamus11.46 ± 0.22
Frontal Lobe12.17 ± 0.52
Globus Pallidus12.48 ± 0.25
Hypothalamus11.88 ± 0.37
Insula12.04 ± 0.57
Limbic Lobe12.17 ± 0.52
Mesencephalon12.18 ± 0.45
Myelencephalon12.12 ± 0.55
Occipital Lobe12.03 ± 0.5
Parietal Lobe12.04 ± 0.44
Pontine Tegmentum11.91 ± 0.4
Striatum12.31 ± 0.47
Subthalamus11.99 ± 0.44
Temporal Lobe12.01 ± 0.54
Thalamus12.18 ± 0.41
White Matter12.17 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ntn1CBCerebellum58.46
50.76
Ntn1CTXCerebral cortex0.79
0.88
Ntn1HIPHippocampal region0.26
0.31
Ntn1HPFHippocampal formation0.39
0.42
Ntn1HYHypothalamus1.17
0.99
Ntn1LSXLateral septal complex0.78
0.54
Ntn1MBMidbrain4.02
6.37
Ntn1MYMedulla3.21
2.73
Ntn1OLFOlfactory bulb1.29
1.12
Ntn1PPons1.85
1.9
Ntn1PALPallidum3.1
3.59
Ntn1RHPRetrohippocampal region0.57
0.53
Ntn1sAMYStriatum-like amygdalar nuclei1.25
1.24
Ntn1STRStriatum3.63
3.49
Ntn1STRdStriatum dorsal region1.54
1.84
Ntn1STRvStriatum ventral region12.48
10.01
Ntn1THThalamus0.49
0.52
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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