AutismKB 2.0

Annotation Detail for TNFSF8


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Basic Information Top
Gene Symbol:TNFSF8 ( CD153,CD30L,CD30LG,MGC138144 )
Gene Full Name: tumor necrosis factor (ligand) superfamily, member 8
Band: 9q32-q33.1
Quick LinksEntrez ID:944; OMIM: 603875; Uniprot ID:TNFL8_HUMAN; ENSEMBL ID: ENSG00000106952; HGNC ID: 11938
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult5 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal16 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis0 / 3304420 
thymus25 / 81131308
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207216_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.95
Adipocyte4.05
AdrenalCortex4.05
Adrenalgland3.4
Amygdala4.2
Appendix4.05
AtrioventricularNode3.05
BDCA4+_DentriticCells4.55
Bonemarrow4
BronchialEpithelialCells3.95
CD105+_Endothelial4.05
CD14+_Monocytes5.2
CD19+_BCells(neg._sel.)4.3
CD33+_Myeloid8.05
CD34+5.15
CD4+_Tcells11.2
CD56+_NKCells4.8
CD71+_EarlyErythroid3.75
CD8+_Tcells6.25
CardiacMyocytes5
Caudatenucleus3.65
Cerebellum3.25
CerebellumPeduncles4.55
CiliaryGanglion2.9
CingulateCortex4.1
Colorectaladenocarcinoma4.05
DorsalRootGanglion3
FetalThyroid3.9
Fetalbrain4.05
Fetalliver3.45
Fetallung3.4
GlobusPallidus2.95
Heart5.05
Hypothalamus4.4
Kidney3.35
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.55
Leukemialymphoblastic(MOLT-4)3.25
Liver5.25
Lung4.4
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.15
Lymphoma_burkitts(Raji)5.55
MedullaOblongata3.7
OccipitalLobe3.65
OlfactoryBulb3.2
Ovary2.7
Pancreas3.25
PancreaticIslet4.3
ParietalLobe4.3
Pituitary4.7
Placenta4.15
Pons3.8
PrefrontalCortex5.05
Prostate4.8
Salivarygland3.2
SkeletalMuscle5.05
Skin3.15
SmoothMuscle4.6
Spinalcord4.3
SubthalamicNucleus3.65
SuperiorCervicalGanglion4.65
TemporalLobe3.65
Testis3.45
TestisGermCell3.4
TestisIntersitial3.4
TestisLeydigCell4
TestisSeminiferousTubule3.5
Thalamus4.1
Thymus3.25
Thyroid5
Tongue3.95
Tonsil3.9
Trachea3.4
TrigeminalGanglion3.95
Uterus3.3
UterusCorpus6.3
WholeBlood4.5
Wholebrain3.4
colon4.05
pineal_day5.02
pineal_night4.9
retina4.825
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7436_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.31 ± 0.99
Basal Forebrain1.88 ± 0.19
Basal Part of Pons1.51 ± 0.35
Cerebellar Cortex1.58 ± 0.58
Cerebellar Nuclei2.14 ± 0.66
Claustrum2.67 ± 0.83
Epithalamus1.56 ± 0.73
Frontal Lobe1.67 ± 0.62
Globus Pallidus2.55 ± 0.56
Hypothalamus1.86 ± 0.67
Insula1.69 ± 0.49
Limbic Lobe1.85 ± 0.61
Mesencephalon1.98 ± 0.66
Myelencephalon1.86 ± 0.67
Occipital Lobe1.81 ± 0.56
Parietal Lobe1.8 ± 0.62
Pontine Tegmentum1.88 ± 0.67
Striatum2.2 ± 0.59
Subthalamus1.99 ± 0.67
Temporal Lobe1.72 ± 0.59
Thalamus1.8 ± 0.57
White Matter2.47 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tnfsf8CBCerebellum1.82
2.12
Tnfsf8CTXCerebral cortex1.51
1.42
Tnfsf8HIPHippocampal region1.02
1.25
Tnfsf8HPFHippocampal formation0.99
0.99
Tnfsf8HYHypothalamus0.22
0.32
Tnfsf8LSXLateral septal complex1.21
1.01
Tnfsf8MBMidbrain0.43
0.62
Tnfsf8MYMedulla0.92
1.02
Tnfsf8OLFOlfactory bulb2.59
2.77
Tnfsf8PPons0.36
0.48
Tnfsf8PALPallidum0.86
0.92
Tnfsf8RHPRetrohippocampal region0.97
0.69
Tnfsf8sAMYStriatum-like amygdalar nuclei0.05
0.06
Tnfsf8STRStriatum0.59
0.5
Tnfsf8STRdStriatum dorsal region0.37
0.3
Tnfsf8STRvStriatum ventral region1.49
1.22
Tnfsf8THThalamus0.71
0.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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