AutismKB 2.0

Annotation Detail for MED26


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Basic Information Top
Gene Symbol:MED26 ( CRSP7,CRSP70 )
Gene Full Name: mediator complex subunit 26
Band: 19p13.11
Quick LinksEntrez ID:9441; OMIM: 605043; Uniprot ID:MED26_HUMAN; ENSEMBL ID: ENSG00000105085; HGNC ID: 2376
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P164737
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.89 ± 0.24
Basal Forebrain7.01 ± 0.17
Basal Part of Pons6.95 ± 0.26
Cerebellar Cortex7.46 ± 0.19
Cerebellar Nuclei6.87 ± 0.29
Claustrum6.82 ± 0.49
Epithalamus7.26 ± 0.3
Frontal Lobe7.1 ± 0.31
Globus Pallidus6.77 ± 0.2
Hypothalamus7.06 ± 0.38
Insula7.29 ± 0.27
Limbic Lobe7.13 ± 0.38
Mesencephalon7.1 ± 0.26
Myelencephalon7.12 ± 0.3
Occipital Lobe7.22 ± 0.21
Parietal Lobe7.08 ± 0.35
Pontine Tegmentum7.13 ± 0.3
Striatum7.01 ± 0.3
Subthalamus7.16 ± 0.22
Temporal Lobe7.16 ± 0.29
Thalamus7.11 ± 0.26
White Matter7.05 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Crsp7CBCerebellum7.7
8.79
Crsp7CTXCerebral cortex11.21
8.81
Crsp7HIPHippocampal region15.25
17.1
Crsp7HPFHippocampal formation11.9
12.05
Crsp7HYHypothalamus0.76
0.78
Crsp7LSXLateral septal complex2.54
2.52
Crsp7MBMidbrain1.13
1.38
Crsp7MYMedulla2.86
3.37
Crsp7OLFOlfactory bulb20.56
17.75
Crsp7PPons1.4
1.91
Crsp7PALPallidum1.42
1.41
Crsp7RHPRetrohippocampal region7.63
6.27
Crsp7sAMYStriatum-like amygdalar nuclei3.56
2.43
Crsp7STRStriatum3.21
2.87
Crsp7STRdStriatum dorsal region3.22
3.08
Crsp7STRvStriatum ventral region2.74
2.13
Crsp7THThalamus2.71
3.08
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010232 27 96 122 GLAGATGSANGGAHNCRPEVGAAGPPR Peptide Atlas

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018