AutismKB 2.0

Annotation Detail for PICK1


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Basic Information Top
Gene Symbol:PICK1 ( MGC15204,PICK,PRKCABP )
Gene Full Name: protein interacting with PRKCA 1
Band: 22q13.1
Quick LinksEntrez ID:9463; OMIM: 605926; Uniprot ID:PICK1_HUMAN; ENSEMBL ID: ENSG00000100151; HGNC ID: 9394
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus37 / 56401265
neonate2 / 3109764
infant0 / 236200 
juvenile3 / 5555653
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor17 / 26384564
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor6 / 6895987
leukemia3 / 9584231
liver tumor5 / 9635951
lung tumor2 / 10312719
lymphoma4 / 7175555
non-neoplasia8 / 9725082
normal232 / 336030769
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor26 / 124949208
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites2 / 4001549
bladder4 / 29757134
blood4 / 12347832
bone4 / 7165555
bone marrow2 / 4880140
brain133 / 1100989120
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye8 / 21105437
heart2 / 8962622
intestine12 / 23447251
kidney19 / 21177789
larynx1 / 2414541
liver7 / 20774333
lung7 / 33697420
lymph1 / 4427022
lymph node0 / 916100 
mammary gland4 / 15327126
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate9 / 18934547
salivary gland1 / 2015549
skin27 / 210574128
spleen8 / 53952148
stomach2 / 9661920
testis17 / 33044251
thymus6 / 8113173
thyroid5 / 47473105
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204746_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte5.3
AdrenalCortex5.9
Adrenalgland4.85
Amygdala5.7
Appendix5.9
AtrioventricularNode4.05
BDCA4+_DentriticCells5.65
Bonemarrow5.4
BronchialEpithelialCells4.9
CD105+_Endothelial5.4
CD14+_Monocytes6.35
CD19+_BCells(neg._sel.)5.65
CD33+_Myeloid6.9
CD34+6.95
CD4+_Tcells6.05
CD56+_NKCells6.6
CD71+_EarlyErythroid5.05
CD8+_Tcells5.3
CardiacMyocytes6.65
Caudatenucleus4.95
Cerebellum4.35
CerebellumPeduncles12.5
CiliaryGanglion3.8
CingulateCortex7.65
Colorectaladenocarcinoma5.3
DorsalRootGanglion5.9
FetalThyroid5.5
Fetalbrain5.45
Fetalliver4.65
Fetallung4.2
GlobusPallidus6.95
Heart6.8
Hypothalamus7.5
Kidney4.4
Leukemia_chronicMyelogenousK-5624.95
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)4.45
Liver7.15
Lung5.95
Lymphnode5.1
Lymphoma_burkitts(Daudi)6.95
Lymphoma_burkitts(Raji)7.5
MedullaOblongata5
OccipitalLobe5.5
OlfactoryBulb4.3
Ovary3.65
Pancreas4.35
PancreaticIslet5.8
ParietalLobe6
Pituitary6.65
Placenta5.25
Pons5.2
PrefrontalCortex8.6
Prostate6.45
Salivarygland5.2
SkeletalMuscle6.4
Skin4.2
SmoothMuscle6.05
Spinalcord6
SubthalamicNucleus4.95
SuperiorCervicalGanglion6.3
TemporalLobe5.2
Testis4.75
TestisGermCell4.65
TestisIntersitial4.5
TestisLeydigCell5.4
TestisSeminiferousTubule4.75
Thalamus8.9
Thymus4.05
Thyroid7
Tongue5.3
Tonsil5.35
Trachea4.55
TrigeminalGanglion5.4
Uterus4.4
UterusCorpus4.8
WholeBlood5.45
Wholebrain4.65
colon5.45
pineal_day7.88
pineal_night6.8
retina6.975
small_intestine5.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13313_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.44 ± 0.5
Basal Forebrain4.33 ± 0.43
Basal Part of Pons4.3 ± 0.38
Cerebellar Cortex4.42 ± 0.36
Cerebellar Nuclei4.27 ± 0.62
Claustrum4.5 ± 0.68
Epithalamus3.9 ± 0.57
Frontal Lobe4.47 ± 0.51
Globus Pallidus4.78 ± 0.59
Hypothalamus4.19 ± 0.69
Insula4.35 ± 0.5
Limbic Lobe4.69 ± 0.49
Mesencephalon4.51 ± 0.55
Myelencephalon4.43 ± 0.51
Occipital Lobe4.73 ± 0.47
Parietal Lobe4.67 ± 0.47
Pontine Tegmentum4.5 ± 0.63
Striatum4.35 ± 0.49
Subthalamus4.06 ± 0.31
Temporal Lobe4.42 ± 0.5
Thalamus4.34 ± 0.49
White Matter5.71 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pick1HYHypothalamus70.2
51.9
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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