AutismKB 2.0

Annotation Detail for AKAP7


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Basic Information Top
Gene Symbol:AKAP7 ( AKAP15,AKAP18 )
Gene Full Name: A kinase (PRKA) anchor protein 7
Band: 6q23.2
Quick LinksEntrez ID:9465; OMIM: 604693; Uniprot ID:AKA7A_HUMAN; ENSEMBL ID: ENSG00000118507; HGNC ID: 377
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus57 / 564012101
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor19 / 26384572
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal122 / 336030736
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain76 / 110098969
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine3 / 23447212
kidney4 / 21177718
larynx1 / 2414541
liver4 / 20774319
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis16 / 33044248
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205771_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.95
Adipocyte7.1
AdrenalCortex12.2
Adrenalgland13.15
Amygdala18.3
Appendix9.1
AtrioventricularNode7.85
BDCA4+_DentriticCells7.7
Bonemarrow8
BronchialEpithelialCells6.85
CD105+_Endothelial24.3
CD14+_Monocytes8.15
CD19+_BCells(neg._sel.)10.65
CD33+_Myeloid9.4
CD34+9.6
CD4+_Tcells14.25
CD56+_NKCells19.6
CD71+_EarlyErythroid90.2
CD8+_Tcells17.8
CardiacMyocytes12.2
Caudatenucleus6.75
Cerebellum6.2
CerebellumPeduncles8.8
CiliaryGanglion6.8
CingulateCortex7.9
Colorectaladenocarcinoma7.25
DorsalRootGanglion7
FetalThyroid7.45
Fetalbrain320.7
Fetalliver8.45
Fetallung6.25
GlobusPallidus6.4
Heart11.15
Hypothalamus8.25
Kidney6.3
Leukemia_chronicMyelogenousK-5626.75
Leukemia_promyelocytic-HL-606.35
Leukemialymphoblastic(MOLT-4)5.65
Liver11
Lung7.75
Lymphnode7.1
Lymphoma_burkitts(Daudi)9.45
Lymphoma_burkitts(Raji)11.1
MedullaOblongata7.2
OccipitalLobe7.8
OlfactoryBulb6.2
Ovary5.5
Pancreas8.85
PancreaticIslet39.6
ParietalLobe8.45
Pituitary8.65
Placenta7.35
Pons7.35
PrefrontalCortex11.75
Prostate10
Salivarygland6.65
SkeletalMuscle10.6
Skin6.75
SmoothMuscle8.3
Spinalcord9.9
SubthalamicNucleus7
SuperiorCervicalGanglion11.3
TemporalLobe7.15
Testis6.45
TestisGermCell6.15
TestisIntersitial7.9
TestisLeydigCell7.65
TestisSeminiferousTubule6.55
Thalamus7.25
Thymus5.9
Thyroid9.25
Tongue7.9
Tonsil7.4
Trachea6.1
TrigeminalGanglion8.8
Uterus7.6
UterusCorpus7.35
WholeBlood8.1
Wholebrain8.15
colon11.85
pineal_day10.82
pineal_night10.12
retina9.375
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6867_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.26 ± 0.4
Basal Forebrain5.7 ± 0.3
Basal Part of Pons5.12 ± 0.44
Cerebellar Cortex5.69 ± 0.59
Cerebellar Nuclei5.27 ± 0.27
Claustrum5.95 ± 0.69
Epithalamus4.87 ± 0.35
Frontal Lobe5.52 ± 0.4
Globus Pallidus5.64 ± 0.5
Hypothalamus5.46 ± 0.5
Insula5.76 ± 0.32
Limbic Lobe5.99 ± 0.47
Mesencephalon5.78 ± 0.49
Myelencephalon5.72 ± 0.52
Occipital Lobe6.41 ± 0.61
Parietal Lobe5.76 ± 0.42
Pontine Tegmentum5.8 ± 0.44
Striatum5.21 ± 0.48
Subthalamus5.62 ± 0.64
Temporal Lobe5.78 ± 0.39
Thalamus5.74 ± 0.44
White Matter4.84 ± 0.89
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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