AutismKB 2.0

Annotation Detail for IL27RA


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Basic Information Top
Gene Symbol:IL27RA ( CRL1,IL27R,TCCR,WSX1,zcytor1 )
Gene Full Name: interleukin 27 receptor, alpha
Band: 19p13.12
Quick LinksEntrez ID:9466; OMIM: 605350; Uniprot ID:I27RA_HUMAN; ENSEMBL ID: ENSG00000104998; HGNC ID: 17290
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal40 / 336030711
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain4 / 11009893
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node11 / 91610120
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid19 / 47473400
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222062_at
Cell line Expression level Expression bar
721_B_lymphoblasts100.25
Adipocyte6
AdrenalCortex7.05
Adrenalgland5.25
Amygdala6.05
Appendix6.75
AtrioventricularNode5.4
BDCA4+_DentriticCells108.25
Bonemarrow6.1
BronchialEpithelialCells6.15
CD105+_Endothelial6.35
CD14+_Monocytes423.4
CD19+_BCells(neg._sel.)312.9
CD33+_Myeloid367.95
CD34+54.6
CD4+_Tcells219.4
CD56+_NKCells343.9
CD71+_EarlyErythroid5.8
CD8+_Tcells185.4
CardiacMyocytes8.65
Caudatenucleus5.55
Cerebellum5
CerebellumPeduncles7.2
CiliaryGanglion4.85
CingulateCortex6.35
Colorectaladenocarcinoma6.45
DorsalRootGanglion5.1
FetalThyroid6.05
Fetalbrain6.4
Fetalliver5.25
Fetallung5.05
GlobusPallidus4.65
Heart8.5
Hypothalamus6.45
Kidney5.3
Leukemia_chronicMyelogenousK-56236.05
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)5.05
Liver8.2
Lung11.7
Lymphnode35.3
Lymphoma_burkitts(Daudi)7.9
Lymphoma_burkitts(Raji)8.75
MedullaOblongata5.65
OccipitalLobe5.55
OlfactoryBulb4.9
Ovary4.3
Pancreas5.1
PancreaticIslet6.75
ParietalLobe6.8
Pituitary7.25
Placenta6.35
Pons5.95
PrefrontalCortex7.4
Prostate7.3
Salivarygland5.1
SkeletalMuscle8.15
Skin5.3
SmoothMuscle7.05
Spinalcord6.65
SubthalamicNucleus5.7
SuperiorCervicalGanglion7.8
TemporalLobe5.7
Testis5.2
TestisGermCell5.2
TestisIntersitial5.25
TestisLeydigCell6.15
TestisSeminiferousTubule5.35
Thalamus6.35
Thymus15.6
Thyroid7.8
Tongue6.35
Tonsil15.65
Trachea5.15
TrigeminalGanglion10.4
Uterus4.95
UterusCorpus5.85
WholeBlood96.75
Wholebrain4.8
colon6.2
pineal_day7.38
pineal_night7.3
retina7.525
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P27606
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.06 ± 0.4
Basal Forebrain5.03 ± 0.77
Basal Part of Pons5.25 ± 0.25
Cerebellar Cortex5.16 ± 0.52
Cerebellar Nuclei4.93 ± 0.47
Claustrum5.61 ± 0.57
Epithalamus5.96 ± 0.68
Frontal Lobe5.52 ± 0.59
Globus Pallidus4.73 ± 0.79
Hypothalamus5.52 ± 0.63
Insula5.65 ± 0.53
Limbic Lobe6.05 ± 0.58
Mesencephalon5.37 ± 0.61
Myelencephalon5.5 ± 0.68
Occipital Lobe5.38 ± 0.6
Parietal Lobe5.84 ± 0.61
Pontine Tegmentum5.48 ± 0.66
Striatum5.04 ± 0.85
Subthalamus5.46 ± 0.73
Temporal Lobe5.59 ± 0.54
Thalamus4.68 ± 0.65
White Matter4.04 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Il27raCBCerebellum0.78
1.57
Il27raCTXCerebral cortex0.22
0.54
Il27raHIPHippocampal region2.71
2.72
Il27raHPFHippocampal formation1.94
1.9
Il27raHYHypothalamus2.46
2.34
Il27raLSXLateral septal complex0.15
0.12
Il27raMBMidbrain0.3
0.52
Il27raMYMedulla0.17
0.27
Il27raOLFOlfactory bulb0.55
1.94
Il27raPPons0.27
0.84
Il27raPALPallidum1.17
1.62
Il27raRHPRetrohippocampal region0.57
0.69
Il27rasAMYStriatum-like amygdalar nuclei0.03
0
Il27raSTRStriatum0.09
0.1
Il27raSTRdStriatum dorsal region0.1
0.14
Il27raSTRvStriatum ventral region0.04
0.04
Il27raTHThalamus0.79
0.87
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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