AutismKB 2.0

Annotation Detail for PCYT1B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PCYT1B ( CCTB,CTB )
Gene Full Name: phosphate cytidylyltransferase 1, choline, beta
Band: Xp22.11
Quick LinksEntrez ID:9468; OMIM: 604926; Uniprot ID:PCY1B_HUMAN; ENSEMBL ID: ENSG00000102230; HGNC ID: 8755
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal47 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain30 / 110098927
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis12 / 33044236
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210456_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.75
Adipocyte12.35
AdrenalCortex18.65
Adrenalgland11.05
Amygdala10.85
Appendix17.4
AtrioventricularNode17.05
BDCA4+_DentriticCells10.85
Bonemarrow23.15
BronchialEpithelialCells12.15
CD105+_Endothelial12.15
CD14+_Monocytes13.15
CD19+_BCells(neg._sel.)11.35
CD33+_Myeloid15.6
CD34+13.65
CD4+_Tcells13.45
CD56+_NKCells11.55
CD71+_EarlyErythroid12
CD8+_Tcells11.35
CardiacMyocytes29.6
Caudatenucleus11.75
Cerebellum11.25
CerebellumPeduncles31.15
CiliaryGanglion14.55
CingulateCortex15.3
Colorectaladenocarcinoma11.9
DorsalRootGanglion15.45
FetalThyroid14.1
Fetalbrain11.8
Fetalliver10.8
Fetallung7.55
GlobusPallidus12.1
Heart28.15
Hypothalamus12.75
Kidney12.5
Leukemia_chronicMyelogenousK-56210.9
Leukemia_promyelocytic-HL-6010.85
Leukemialymphoblastic(MOLT-4)8.25
Liver26.6
Lung16.4
Lymphnode10.6
Lymphoma_burkitts(Daudi)16.45
Lymphoma_burkitts(Raji)24.8
MedullaOblongata10.65
OccipitalLobe10.35
OlfactoryBulb10.2
Ovary10.1
Pancreas11.2
PancreaticIslet14.1
ParietalLobe14.95
Pituitary14.65
Placenta10.55
Pons15.75
PrefrontalCortex11.9
Prostate14.1
Salivarygland11
SkeletalMuscle25.4
Skin15.1
SmoothMuscle16.35
Spinalcord12.1
SubthalamicNucleus21.9
SuperiorCervicalGanglion23.75
TemporalLobe12.45
Testis9.6
TestisGermCell10.65
TestisIntersitial10.35
TestisLeydigCell13.25
TestisSeminiferousTubule10.25
Thalamus17.55
Thymus9.1
Thyroid13.85
Tongue21.75
Tonsil23.85
Trachea10.75
TrigeminalGanglion16.65
Uterus9.4
UterusCorpus15.85
WholeBlood11.4
Wholebrain8.05
colon15
pineal_day21.7
pineal_night18.62
retina16.025
small_intestine14
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P941353
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.45
Basal Forebrain5.33 ± 0.32
Basal Part of Pons5.64 ± 0.13
Cerebellar Cortex4.8 ± 0.31
Cerebellar Nuclei5.25 ± 0.41
Claustrum5.21 ± 0.55
Epithalamus5.18 ± 0.33
Frontal Lobe5.22 ± 0.39
Globus Pallidus5.42 ± 0.3
Hypothalamus4.45 ± 0.4
Insula5.14 ± 0.26
Limbic Lobe5.29 ± 0.4
Mesencephalon4.98 ± 0.46
Myelencephalon5.16 ± 0.42
Occipital Lobe5.09 ± 0.36
Parietal Lobe5.12 ± 0.4
Pontine Tegmentum5.15 ± 0.45
Striatum5.38 ± 0.42
Subthalamus4.63 ± 0.46
Temporal Lobe5.27 ± 0.4
Thalamus5.36 ± 0.37
White Matter5.8 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pcyt1bCBCerebellum29.73
42.72
Pcyt1bCTXCerebral cortex35.83
27.12
Pcyt1bHIPHippocampal region22.74
29.66
Pcyt1bHPFHippocampal formation24.76
27
Pcyt1bHYHypothalamus12.79
10.41
Pcyt1bLSXLateral septal complex15.95
14.17
Pcyt1bMBMidbrain17.47
18.65
Pcyt1bMYMedulla44.31
59.77
Pcyt1bOLFOlfactory bulb54.77
49.75
Pcyt1bPPons32.91
38.99
Pcyt1bPALPallidum17.42
16.95
Pcyt1bRHPRetrohippocampal region28.04
24.71
Pcyt1bsAMYStriatum-like amygdalar nuclei21.01
16.31
Pcyt1bSTRStriatum16.61
13.55
Pcyt1bSTRdStriatum dorsal region13
10.59
Pcyt1bSTRvStriatum ventral region25.14
19.22
Pcyt1bTHThalamus21.92
19.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00070060 21 163 183 IDFVAHDDIPYSSAGSDDVYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved