AutismKB 2.0

Annotation Detail for NAPSA


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Basic Information Top
Gene Symbol:NAPSA ( KAP,Kdap,NAP1,NAPA,SNAPA )
Gene Full Name: napsin A aspartic peptidase
Band: 19q13.33
Quick LinksEntrez ID:9476; OMIM: 605631; Uniprot ID:NAPSA_HUMAN; ENSEMBL ID: ENSG00000131400; HGNC ID: 13395
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal72 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer7 / 10268068
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine1 / 2344724
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung51 / 336974151
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate7 / 18934536
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P107029
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.62 ± 0.8
Basal Forebrain4.43 ± 0.36
Basal Part of Pons4.61 ± 0.41
Cerebellar Cortex4.5 ± 0.6
Cerebellar Nuclei4.58 ± 0.51
Claustrum4.76 ± 0.73
Epithalamus4.46 ± 0.31
Frontal Lobe4.36 ± 0.67
Globus Pallidus5.3 ± 0.69
Hypothalamus4.4 ± 0.6
Insula4.37 ± 0.87
Limbic Lobe4.56 ± 0.74
Mesencephalon4.58 ± 0.7
Myelencephalon4.55 ± 0.65
Occipital Lobe4.47 ± 0.69
Parietal Lobe4.49 ± 0.71
Pontine Tegmentum4.25 ± 0.76
Striatum4.63 ± 0.64
Subthalamus4.71 ± 0.37
Temporal Lobe4.48 ± 0.64
Thalamus4.4 ± 0.63
White Matter4.22 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NapsaCBCerebellum1.35
1.73
NapsaCTXCerebral cortex0.86
1.07
NapsaHIPHippocampal region0.91
1.36
NapsaHPFHippocampal formation0.79
1.14
NapsaHYHypothalamus0.07
0.05
NapsaLSXLateral septal complex0.04
0
NapsaMBMidbrain0.99
1.41
NapsaMYMedulla1.67
1.91
NapsaOLFOlfactory bulb1.04
0.96
NapsaPPons2.27
2.64
NapsaPALPallidum0.44
0.78
NapsaRHPRetrohippocampal region0.62
0.9
NapsasAMYStriatum-like amygdalar nuclei0.05
0.08
NapsaSTRStriatum0.36
0.6
NapsaSTRdStriatum dorsal region0.45
0.85
NapsaSTRvStriatum ventral region0.36
0.33
NapsaTHThalamus0.58
0.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00038580 16 146 161 VDGILSEDKLTIGGIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018