AutismKB 2.0

Annotation Detail for MAPK8IP1


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Basic Information Top
Gene Symbol:MAPK8IP1 ( IB1,JIP-1,JIP1,PRKM8IP )
Gene Full Name: mitogen-activated protein kinase 8 interacting protein 1
Band: 11p11.2
Quick LinksEntrez ID:9479; OMIM: 604641; Uniprot ID:JIP1_HUMAN; ENSEMBL ID: ENSG00000121653; HGNC ID: 6882
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant5 / 23620211
juvenile2 / 5555635
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal111 / 336030733
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain78 / 110098970
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye14 / 21105466
heart1 / 8962611
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle3 / 10771527
nerve3 / 15768190
ovary2 / 10205119
pancreas12 / 21481255
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland7 / 16585422
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213013_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.6
Adipocyte33.05
AdrenalCortex78.7
Adrenalgland39.3
Amygdala88.35
Appendix64.15
AtrioventricularNode75.4
BDCA4+_DentriticCells23.4
Bonemarrow41.9
BronchialEpithelialCells27.25
CD105+_Endothelial35.85
CD14+_Monocytes22.45
CD19+_BCells(neg._sel.)21.7
CD33+_Myeloid35.25
CD34+33.6
CD4+_Tcells27.9
CD56+_NKCells30.95
CD71+_EarlyErythroid38.55
CD8+_Tcells24.6
CardiacMyocytes53.5
Caudatenucleus74.9
Cerebellum40.4
CerebellumPeduncles134.8
CiliaryGanglion66.8
CingulateCortex113.4
Colorectaladenocarcinoma38.3
DorsalRootGanglion70.1
FetalThyroid43.95
Fetalbrain187.55
Fetalliver28.25
Fetallung22.75
GlobusPallidus50.85
Heart62.85
Hypothalamus94.35
Kidney36.2
Leukemia_chronicMyelogenousK-56234.2
Leukemia_promyelocytic-HL-6027.1
Leukemialymphoblastic(MOLT-4)25.4
Liver74.25
Lung44.05
Lymphnode24.05
Lymphoma_burkitts(Daudi)48.2
Lymphoma_burkitts(Raji)56.7
MedullaOblongata75.75
OccipitalLobe78.25
OlfactoryBulb142.35
Ovary28
Pancreas36.15
PancreaticIslet67.9
ParietalLobe84.85
Pituitary86.15
Placenta25.55
Pons162.2
PrefrontalCortex120.1
Prostate48.25
Salivarygland28.75
SkeletalMuscle80.45
Skin34.9
SmoothMuscle44
Spinalcord135.55
SubthalamicNucleus118.1
SuperiorCervicalGanglion57.15
TemporalLobe167
Testis39.75
TestisGermCell62.25
TestisIntersitial71.1
TestisLeydigCell56.85
TestisSeminiferousTubule77.25
Thalamus187.9
Thymus22.9
Thyroid51.5
Tongue55.25
Tonsil39.55
Trachea30.95
TrigeminalGanglion111.6
Uterus28.45
UterusCorpus37.2
WholeBlood17.95
Wholebrain121.55
colon25.9
pineal_day95.84
pineal_night83.54
retina79.925
small_intestine25.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6142_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.98 ± 0.22
Basal Forebrain7.81 ± 0.36
Basal Part of Pons7.86 ± 0.37
Cerebellar Cortex7.59 ± 0.2
Cerebellar Nuclei7.6 ± 0.3
Claustrum8.15 ± 0.36
Epithalamus7.22 ± 0.47
Frontal Lobe7.94 ± 0.31
Globus Pallidus8 ± 0.34
Hypothalamus7.46 ± 0.38
Insula7.96 ± 0.24
Limbic Lobe8.19 ± 0.32
Mesencephalon7.8 ± 0.29
Myelencephalon7.88 ± 0.37
Occipital Lobe7.44 ± 0.35
Parietal Lobe7.77 ± 0.35
Pontine Tegmentum7.79 ± 0.34
Striatum7.66 ± 0.37
Subthalamus7.56 ± 0.16
Temporal Lobe7.99 ± 0.31
Thalamus7.72 ± 0.27
White Matter9.3 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mapk8ip1CBCerebellum100
100
Mapk8ip1CTXCerebral cortex100
100
Mapk8ip1HIPHippocampal region100
100
Mapk8ip1HPFHippocampal formation100
100
Mapk8ip1HYHypothalamus100
99.38
Mapk8ip1LSXLateral septal complex100
100
Mapk8ip1MBMidbrain100
100
Mapk8ip1MYMedulla100
100
Mapk8ip1OLFOlfactory bulb100
100
Mapk8ip1PPons100
100
Mapk8ip1PALPallidum100
100
Mapk8ip1RHPRetrohippocampal region100
100
Mapk8ip1sAMYStriatum-like amygdalar nuclei95.87
85.07
Mapk8ip1STRStriatum100
100
Mapk8ip1STRdStriatum dorsal region100
100
Mapk8ip1STRvStriatum ventral region100
100
Mapk8ip1THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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