AutismKB 2.0

Annotation Detail for SLC25A27


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Basic Information Top
Gene Symbol:SLC25A27 ( FLJ33552,UCP4 )
Gene Full Name: solute carrier family 25, member 27
Band: 6p12.3
Quick LinksEntrez ID:9481; OMIM: NA; Uniprot ID:UCP4_HUMAN; ENSEMBL ID: ENSG00000153291; HGNC ID: 21065
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus42 / 56401274
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal119 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain75 / 110098968
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine1 / 2344724
kidney8 / 21177737
larynx0 / 241450 
liver2 / 2077439
lung11 / 33697432
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta0 / 2808250 
prostate12 / 18934563
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P246841
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.07 ± 0.18
Basal Forebrain9.15 ± 0.12
Basal Part of Pons9.33 ± 0.22
Cerebellar Cortex9.46 ± 0.17
Cerebellar Nuclei9.26 ± 0.19
Claustrum9.29 ± 0.17
Epithalamus8.78 ± 0.48
Frontal Lobe9.11 ± 0.28
Globus Pallidus8.51 ± 0.22
Hypothalamus9.23 ± 0.22
Insula9.35 ± 0.34
Limbic Lobe9.1 ± 0.37
Mesencephalon9.31 ± 0.35
Myelencephalon9.15 ± 0.31
Occipital Lobe9.09 ± 0.26
Parietal Lobe9.26 ± 0.26
Pontine Tegmentum9.09 ± 0.26
Striatum9.18 ± 0.3
Subthalamus9.19 ± 0.21
Temporal Lobe9.33 ± 0.26
Thalamus9.37 ± 0.27
White Matter9.15 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc25a27CBCerebellum62.41
59.75
Slc25a27CTXCerebral cortex100
73.15
Slc25a27HIPHippocampal region65.33
64.23
Slc25a27HPFHippocampal formation83.74
66.92
Slc25a27HYHypothalamus79.69
55.17
Slc25a27LSXLateral septal complex82.63
52.92
Slc25a27MBMidbrain77.15
60.43
Slc25a27MYMedulla90.89
68.3
Slc25a27OLFOlfactory bulb100
82.42
Slc25a27PPons85.3
65.09
Slc25a27PALPallidum84.24
62.35
Slc25a27RHPRetrohippocampal region98.24
69.24
Slc25a27sAMYStriatum-like amygdalar nuclei85.44
57.34
Slc25a27STRStriatum100
76.38
Slc25a27STRdStriatum dorsal region100
80.51
Slc25a27STRvStriatum ventral region100
76.92
Slc25a27THThalamus91.71
66.67
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018