AutismKB 2.0

Annotation Detail for PIGB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PIGB ( MGC21236 )
Gene Full Name: phosphatidylinositol glycan anchor biosynthesis, class B
Band: 15q21.3
Quick LinksEntrez ID:9488; OMIM: 604122; Uniprot ID:PIGB_HUMAN; ENSEMBL ID: ENSG00000069943; HGNC ID: 8959
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate3 / 3109796
infant0 / 236200 
juvenile5 / 5555689
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor3 / 17290173
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma3 / 10688328
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal73 / 336030721
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder2 / 2975767
blood4 / 12347832
bone0 / 716550 
bone marrow2 / 4880140
brain20 / 110098918
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus3 / 20209148
eye2 / 2110549
heart0 / 896260 
intestine4 / 23447217
kidney5 / 21177723
larynx0 / 241450 
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach2 / 9661920
testis9 / 33044227
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205452_at
Cell line Expression level Expression bar
721_B_lymphoblasts74.6
Adipocyte9.8
AdrenalCortex12.05
Adrenalgland8.4
Amygdala10.45
Appendix11.6
AtrioventricularNode8.05
BDCA4+_DentriticCells16.5
Bonemarrow9.9
BronchialEpithelialCells9.85
CD105+_Endothelial14.4
CD14+_Monocytes11.05
CD19+_BCells(neg._sel.)24.75
CD33+_Myeloid31
CD34+15.55
CD4+_Tcells14.85
CD56+_NKCells19.4
CD71+_EarlyErythroid9.4
CD8+_Tcells20.1
CardiacMyocytes12.95
Caudatenucleus9.05
Cerebellum8
CerebellumPeduncles11.2
CiliaryGanglion7.05
CingulateCortex10.3
Colorectaladenocarcinoma9.15
DorsalRootGanglion9.5
FetalThyroid9.8
Fetalbrain9.95
Fetalliver8.65
Fetallung7.95
GlobusPallidus7.45
Heart12.55
Hypothalamus12.85
Kidney8.05
Leukemia_chronicMyelogenousK-56213.8
Leukemia_promyelocytic-HL-608.95
Leukemialymphoblastic(MOLT-4)7.9
Liver12.95
Lung10.4
Lymphnode10.9
Lymphoma_burkitts(Daudi)13.35
Lymphoma_burkitts(Raji)13.85
MedullaOblongata8.7
OccipitalLobe9
OlfactoryBulb7.8
Ovary6.8
Pancreas7.9
PancreaticIslet10.95
ParietalLobe10.65
Pituitary19.45
Placenta10.25
Pons9.65
PrefrontalCortex12.25
Prostate11.7
Salivarygland8.35
SkeletalMuscle11.6
Skin7.75
SmoothMuscle11.3
Spinalcord10.7
SubthalamicNucleus9.25
SuperiorCervicalGanglion12.65
TemporalLobe9.1
Testis8.55
TestisGermCell11.9
TestisIntersitial10.65
TestisLeydigCell10
TestisSeminiferousTubule9.7
Thalamus10
Thymus7.75
Thyroid13.2
Tongue9.9
Tonsil10
Trachea8.45
TrigeminalGanglion17.55
Uterus7.7
UterusCorpus8.95
WholeBlood42.2
Wholebrain7.3
colon10.1
pineal_day16.24
pineal_night15.32
retina12.675
small_intestine9.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5580_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.01 ± 0.69
Basal Forebrain3.6 ± 0.38
Basal Part of Pons3.76 ± 0.41
Cerebellar Cortex3.65 ± 0.49
Cerebellar Nuclei3.91 ± 0.58
Claustrum4.07 ± 0.85
Epithalamus3.74 ± 0.3
Frontal Lobe3.64 ± 0.55
Globus Pallidus3.72 ± 0.48
Hypothalamus3.64 ± 0.39
Insula3.59 ± 0.3
Limbic Lobe3.65 ± 0.48
Mesencephalon3.59 ± 0.65
Myelencephalon3.66 ± 0.63
Occipital Lobe3.77 ± 0.57
Parietal Lobe3.65 ± 0.59
Pontine Tegmentum3.76 ± 0.55
Striatum3.9 ± 0.63
Subthalamus3.73 ± 0.55
Temporal Lobe3.67 ± 0.54
Thalamus3.6 ± 0.63
White Matter3.3 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PigbCBCerebellum4.66
6.64
PigbCTXCerebral cortex0.86
0.72
PigbHIPHippocampal region2.41
2.19
PigbHPFHippocampal formation1.59
1.38
PigbHYHypothalamus0.13
0.08
PigbLSXLateral septal complex0.87
0.91
PigbMBMidbrain1.19
1.23
PigbMYMedulla2.95
2.94
PigbOLFOlfactory bulb3.87
3.46
PigbPPons0.99
1.26
PigbPALPallidum1.26
2.64
PigbRHPRetrohippocampal region0.36
0.34
PigbsAMYStriatum-like amygdalar nuclei0.44
0.33
PigbSTRStriatum0.52
0.59
PigbSTRdStriatum dorsal region0.34
0.31
PigbSTRvStriatum ventral region1.02
1.61
PigbTHThalamus0.7
0.88
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved