AutismKB 2.0

Annotation Detail for SCARB1


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Basic Information Top
Gene Symbol:SCARB1 ( CD36L1,CLA-1,CLA1,MGC138242,SR-BI,SRB1 )
Gene Full Name: scavenger receptor class B, member 1
Band: 12q24.31
Quick LinksEntrez ID:949; OMIM: 601040; Uniprot ID:SCRB1_HUMAN; ENSEMBL ID: ENSG00000073060; HGNC ID: 1664
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201819_at
Cell line Expression level Expression bar
721_B_lymphoblasts56.75
Adipocyte7.95
AdrenalCortex1496.55
Adrenalgland1168.3
Amygdala10
Appendix12.4
AtrioventricularNode5.75
BDCA4+_DentriticCells42.3
Bonemarrow7.3
BronchialEpithelialCells18.75
CD105+_Endothelial7.4
CD14+_Monocytes7.85
CD19+_BCells(neg._sel.)7.8
CD33+_Myeloid9.05
CD34+11.8
CD4+_Tcells6.95
CD56+_NKCells7.8
CD71+_EarlyErythroid7
CD8+_Tcells6.3
CardiacMyocytes9.3
Caudatenucleus14
Cerebellum6.3
CerebellumPeduncles8.25
CiliaryGanglion5.3
CingulateCortex8.7
Colorectaladenocarcinoma11.75
DorsalRootGanglion5.7
FetalThyroid7.25
Fetalbrain7.4
Fetalliver20.1
Fetallung10.85
GlobusPallidus5.6
Heart9.6
Hypothalamus8.7
Kidney6.05
Leukemia_chronicMyelogenousK-56215.15
Leukemia_promyelocytic-HL-6012.05
Leukemialymphoblastic(MOLT-4)6.35
Liver208.95
Lung28.05
Lymphnode12.45
Lymphoma_burkitts(Daudi)10.1
Lymphoma_burkitts(Raji)32.35
MedullaOblongata8.95
OccipitalLobe7.05
OlfactoryBulb7.75
Ovary5
Pancreas42.65
PancreaticIslet8.35
ParietalLobe8.7
Pituitary8.65
Placenta216.8
Pons7.3
PrefrontalCortex21.6
Prostate11.4
Salivarygland5.95
SkeletalMuscle8.8
Skin6.25
SmoothMuscle8.4
Spinalcord8.2
SubthalamicNucleus6.65
SuperiorCervicalGanglion8.9
TemporalLobe7.25
Testis11.05
TestisGermCell9.7
TestisIntersitial11.35
TestisLeydigCell8.9
TestisSeminiferousTubule6.75
Thalamus8.05
Thymus6.1
Thyroid10.25
Tongue7.55
Tonsil9.85
Trachea6.4
TrigeminalGanglion8.8
Uterus6.25
UterusCorpus9
WholeBlood8.2
Wholebrain6.85
colon7.5
pineal_day9.2
pineal_night9.3
retina10.675
small_intestine7.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P369201
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.62 ± 0.91
Basal Forebrain1.98 ± 0.24
Basal Part of Pons2.05 ± 0.77
Cerebellar Cortex2.08 ± 0.66
Cerebellar Nuclei2.54 ± 0.72
Claustrum2.91 ± 0.83
Epithalamus1.96 ± 0.87
Frontal Lobe2.15 ± 0.73
Globus Pallidus2.92 ± 1
Hypothalamus2.03 ± 0.74
Insula1.99 ± 0.57
Limbic Lobe2.26 ± 0.75
Mesencephalon2.37 ± 0.8
Myelencephalon2.38 ± 0.72
Occipital Lobe2.66 ± 0.88
Parietal Lobe2.34 ± 0.91
Pontine Tegmentum2.46 ± 0.83
Striatum3.16 ± 0.7
Subthalamus2.27 ± 0.67
Temporal Lobe2.29 ± 0.7
Thalamus2.53 ± 0.67
White Matter2.29 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scarb1CBCerebellum55.38
48.94
Scarb1CTXCerebral cortex50.84
30.81
Scarb1HIPHippocampal region61.07
44.27
Scarb1HPFHippocampal formation64.75
45.88
Scarb1HYHypothalamus43.83
24.94
Scarb1LSXLateral septal complex43.87
23.03
Scarb1MBMidbrain36.59
25.23
Scarb1MYMedulla60.51
49.13
Scarb1OLFOlfactory bulb81.64
43.59
Scarb1PPons56.39
44.23
Scarb1PALPallidum29.59
19.2
Scarb1RHPRetrohippocampal region69.8
46.81
Scarb1sAMYStriatum-like amygdalar nuclei41.89
26.99
Scarb1STRStriatum36.14
19.59
Scarb1STRdStriatum dorsal region27.06
14.8
Scarb1STRvStriatum ventral region63.49
30.45
Scarb1THThalamus58.84
41.62
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00523319 12 289 300 ESGVFEGIPTYR Peptide Atlas

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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