AutismKB 2.0

Annotation Detail for LITAF


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Basic Information Top
Gene Symbol:LITAF ( FLJ38636,MGC116698,MGC116700,MGC116701,MGC125274,MGC125275,MGC125276,PIG7,SIMPLE,TP53I7 )
Gene Full Name: lipopolysaccharide-induced TNF factor
Band: 16p13.13
Quick LinksEntrez ID:9516; OMIM: 603795; Uniprot ID:LITAF_HUMAN; ENSEMBL ID: ENSG00000189067; HGNC ID: 16841
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst11 / 62319176
fetus76 / 564012134
neonate25 / 31097803
infant0 / 236200 
juvenile17 / 55556305
adult358 / 1939121184
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma1 / 1747557
breast (mammary gland) tumor24 / 94178254
cervical tumor12 / 34366349
chondrosarcoma15 / 82823181
colorectal tumor11 / 11424696
esophageal tumor6 / 17290347
gastrointestinal tumor16 / 119369134
germ cell tumor44 / 263845166
glioma22 / 106883205
head and neck tumor17 / 136302124
kidney tumor19 / 68959275
leukemia17 / 95842177
liver tumor13 / 96359134
lung tumor18 / 103127174
lymphoma10 / 71755139
non-neoplasia32 / 97250329
normal831 / 3360307247
ovarian tumor10 / 76682130
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor34 / 124949272
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland12 / 33197361
ascites6 / 40015149
bladder11 / 29757369
blood121 / 123478979
bone7 / 7165597
bone marrow6 / 48801122
brain194 / 1100989176
cervix17 / 48171352
connective tissue40 / 149255267
ear14 / 16212863
embryonic tissue30 / 215722139
esophagus6 / 20209296
eye24 / 211054113
heart26 / 89626290
intestine51 / 234472217
kidney54 / 211777254
larynx4 / 24145165
liver28 / 207743134
lung106 / 336974314
lymph6 / 44270135
lymph node4 / 9161043
mammary gland35 / 153271228
mouth8 / 67052119
muscle6 / 10771555
nerve1 / 1576863
ovary14 / 102051137
pancreas27 / 214812125
parathyroid5 / 20539243
pharynx27 / 41328653
pituitary gland1 / 1658560
placenta68 / 280825242
prostate57 / 189345301
salivary gland3 / 20155148
skin58 / 210574275
spleen52 / 53952963
stomach12 / 96619124
testis17 / 33044251
thymus32 / 81131394
thyroid9 / 47473189
tonsil1 / 1699958
trachea13 / 52413248
umbilical cord0 / 136800 
uterus80 / 232878343
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200704_at
Cell line Expression level Expression bar
721_B_lymphoblasts1032.95
Adipocyte75
AdrenalCortex151.4
Adrenalgland99.8
Amygdala137.45
Appendix122.85
AtrioventricularNode117.45
BDCA4+_DentriticCells1318.5
Bonemarrow615.4
BronchialEpithelialCells737.8
CD105+_Endothelial96.4
CD14+_Monocytes1325.3
CD19+_BCells(neg._sel.)1439.85
CD33+_Myeloid907.4
CD34+380.5
CD4+_Tcells1156.85
CD56+_NKCells4418.2
CD71+_EarlyErythroid44
CD8+_Tcells1277.95
CardiacMyocytes44.6
Caudatenucleus161.3
Cerebellum49.7
CerebellumPeduncles85.95
CiliaryGanglion171.7
CingulateCortex61.55
Colorectaladenocarcinoma113.85
DorsalRootGanglion216.25
FetalThyroid496.6
Fetalbrain85.5
Fetalliver28
Fetallung686.9
GlobusPallidus54.95
Heart99.5
Hypothalamus285.65
Kidney207.25
Leukemia_chronicMyelogenousK-562224.35
Leukemia_promyelocytic-HL-6064.7
Leukemialymphoblastic(MOLT-4)18.25
Liver156.1
Lung885.1
Lymphnode449.5
Lymphoma_burkitts(Daudi)290.4
Lymphoma_burkitts(Raji)126.85
MedullaOblongata147.55
OccipitalLobe139.4
OlfactoryBulb606.15
Ovary180.85
Pancreas117.35
PancreaticIslet264.45
ParietalLobe135.95
Pituitary98.35
Placenta851
Pons95.7
PrefrontalCortex95.25
Prostate739.95
Salivarygland454.1
SkeletalMuscle76.5
Skin161.5
SmoothMuscle337.35
Spinalcord562.05
SubthalamicNucleus67.95
SuperiorCervicalGanglion116
TemporalLobe66.9
Testis39.05
TestisGermCell47.7
TestisIntersitial35.25
TestisLeydigCell71.85
TestisSeminiferousTubule38.4
Thalamus221.65
Thymus191.9
Thyroid1075.8
Tongue61.1
Tonsil388.5
Trachea485.6
TrigeminalGanglion150.9
Uterus318.55
UterusCorpus616.65
WholeBlood5190.9
Wholebrain103.4
colon294.1
pineal_day80.02
pineal_night78.8
retina685.5
small_intestine181.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P3532
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.3 ± 0.7
Basal Forebrain5.49 ± 0.32
Basal Part of Pons4.82 ± 0.76
Cerebellar Cortex4.35 ± 0.42
Cerebellar Nuclei6.03 ± 0.52
Claustrum4.05 ± 0.64
Epithalamus5.34 ± 0.57
Frontal Lobe5.01 ± 0.79
Globus Pallidus6.86 ± 0.38
Hypothalamus4.91 ± 0.49
Insula4.43 ± 0.45
Limbic Lobe4.44 ± 0.79
Mesencephalon5.13 ± 0.88
Myelencephalon5.02 ± 0.72
Occipital Lobe4.68 ± 0.72
Parietal Lobe4.66 ± 0.87
Pontine Tegmentum5.07 ± 0.67
Striatum5.68 ± 0.54
Subthalamus5.64 ± 0.39
Temporal Lobe4.6 ± 0.72
Thalamus5.4 ± 0.63
White Matter7.88 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
LitafCBCerebellum5.38
5.77
LitafCTXCerebral cortex6.52
4.98
LitafHIPHippocampal region2.8
2.2
LitafHPFHippocampal formation3.99
2.92
LitafHYHypothalamus2.49
1.75
LitafLSXLateral septal complex1.76
1.02
LitafMBMidbrain4.93
4.24
LitafMYMedulla6.66
5.11
LitafOLFOlfactory bulb8.74
8.1
LitafPPons5.38
4.98
LitafPALPallidum3.47
2.47
LitafRHPRetrohippocampal region5.7
3.73
LitafsAMYStriatum-like amygdalar nuclei2.96
2.8
LitafSTRStriatum4.21
2.91
LitafSTRdStriatum dorsal region5.23
3.45
LitafSTRvStriatum ventral region2.82
2.28
LitafTHThalamus2.86
1.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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