AutismKB 2.0

Annotation Detail for GMFG


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Basic Information Top
Gene Symbol:GMFG ( GMF-GAMMA,MGC126867 )
Gene Full Name: glia maturation factor, gamma
Band: 19q13.2
Quick LinksEntrez ID:9535; OMIM: 604104; Uniprot ID:GMFG_HUMAN; ENSEMBL ID: ENSG00000130755; HGNC ID: 4374
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus29 / 56401251
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma6 / 7175583
non-neoplasia0 / 972500 
normal111 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood15 / 123478121
bone0 / 716550 
bone marrow12 / 48801245
brain3 / 11009892
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart4 / 8962644
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung14 / 33697441
lymph3 / 4427067
lymph node9 / 9161098
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid3 / 20539146
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta6 / 28082521
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach4 / 9661941
testis6 / 33044218
thymus2 / 8113124
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204220_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.95
Adipocyte4.75
AdrenalCortex5.75
Adrenalgland4.05
Amygdala4.95
Appendix5.2
AtrioventricularNode3.85
BDCA4+_DentriticCells662.15
Bonemarrow245.55
BronchialEpithelialCells4.45
CD105+_Endothelial259.65
CD14+_Monocytes1459.8
CD19+_BCells(neg._sel.)977.9
CD33+_Myeloid1375.5
CD34+1227.75
CD4+_Tcells973.9
CD56+_NKCells1211.95
CD71+_EarlyErythroid10.8
CD8+_Tcells772.3
CardiacMyocytes7.2
Caudatenucleus4.4
Cerebellum3.9
CerebellumPeduncles5.6
CiliaryGanglion3.75
CingulateCortex5.1
Colorectaladenocarcinoma6.2
DorsalRootGanglion3.7
FetalThyroid5.55
Fetalbrain4.5
Fetalliver4.25
Fetallung18.5
GlobusPallidus3.75
Heart8.95
Hypothalamus5.25
Kidney3.9
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)135.55
Liver6.8
Lung71.7
Lymphnode96.5
Lymphoma_burkitts(Daudi)201.85
Lymphoma_burkitts(Raji)7.35
MedullaOblongata4.25
OccipitalLobe4.4
OlfactoryBulb3.8
Ovary3.4
Pancreas4.05
PancreaticIslet10.55
ParietalLobe5.15
Pituitary5.6
Placenta13.15
Pons4.7
PrefrontalCortex5.5
Prostate6.15
Salivarygland6.05
SkeletalMuscle9.85
Skin3.7
SmoothMuscle5.05
Spinalcord5.25
SubthalamicNucleus4.45
SuperiorCervicalGanglion5.4
TemporalLobe4.5
Testis4.15
TestisGermCell3.95
TestisIntersitial4.05
TestisLeydigCell4.85
TestisSeminiferousTubule4.15
Thalamus5
Thymus356.3
Thyroid6.2
Tongue5.1
Tonsil65.65
Trachea4.05
TrigeminalGanglion5.2
Uterus4
UterusCorpus4.35
WholeBlood1576.45
Wholebrain3.9
colon4.9
pineal_day6.32
pineal_night5.94
retina5.9
small_intestine6.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10353_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.87 ± 0.57
Basal Forebrain3.92 ± 0.38
Basal Part of Pons4.5 ± 0.59
Cerebellar Cortex3.6 ± 0.37
Cerebellar Nuclei4.77 ± 0.37
Claustrum3.8 ± 1.05
Epithalamus4.36 ± 0.69
Frontal Lobe4.04 ± 0.47
Globus Pallidus5.16 ± 0.28
Hypothalamus3.9 ± 1.07
Insula3.98 ± 0.31
Limbic Lobe3.87 ± 0.64
Mesencephalon4.02 ± 0.66
Myelencephalon4.05 ± 0.62
Occipital Lobe3.8 ± 0.48
Parietal Lobe3.79 ± 0.7
Pontine Tegmentum3.99 ± 0.55
Striatum4.66 ± 0.44
Subthalamus4.2 ± 0.18
Temporal Lobe4.01 ± 0.57
Thalamus4.02 ± 0.51
White Matter4.78 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GmfgCBCerebellum4.36
7.98
GmfgCTXCerebral cortex2.8
3.37
GmfgHIPHippocampal region1.25
1.65
GmfgHPFHippocampal formation1.51
1.87
GmfgHYHypothalamus0.28
0.43
GmfgLSXLateral septal complex0.81
1.41
GmfgMBMidbrain1.41
2.03
GmfgMYMedulla0.62
1.2
GmfgOLFOlfactory bulb1.48
1.55
GmfgPPons0.83
1.89
GmfgPALPallidum0.28
0.32
GmfgRHPRetrohippocampal region1.63
1.68
GmfgsAMYStriatum-like amygdalar nuclei0.44
0.49
GmfgSTRStriatum2.86
3.89
GmfgSTRdStriatum dorsal region4.02
5.58
GmfgSTRvStriatum ventral region0.58
0.54
GmfgTHThalamus4.32
6.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GMFG_HUMAN_0 0 0 0 LVQTAELTK PRIDE
GMFG_HUMAN_0 0 0 0 TTDDLTEAWLQEK PRIDE
GMFG_HUMAN_110 9 110 118 LVQTAELTK PRIDE
GMFG_HUMAN_124 13 124 136 TTDDLTEAWLQEK PRIDE
GMFG_HUMAN_2 18 2 19 SDSLVVCEVDPELTEKLR PRIDE
GMFG_HUMAN_25 10 25 34 ETDNAAIIMK PRIDE
GMFG_HUMAN_40 18 40 57 QMVVLEEEFQNISPEELK PRIDE
GMFG_HUMAN_41 18 41 58 QMVVLEEEFQNISPEELK PRIDE
GMFG_HUMAN_58 9 58 66 MELPERQPR PRIDE
PAp00028571 27 82 108 VSYPLCFIFSSPVGCKPEQQMMYAGSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018