AutismKB 2.0

Annotation Detail for TP53I11


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Basic Information Top
Gene Symbol:TP53I11 ( PIG11 )
Gene Full Name: tumor protein p53 inducible protein 11
Band: 11p11.2
Quick LinksEntrez ID:9537; OMIM: NA; Uniprot ID:P5I11_HUMAN; ENSEMBL ID: ENSG00000175274; HGNC ID: 16842
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst8 / 62319128
fetus111 / 564012196
neonate1 / 3109732
infant1 / 2362042
juvenile3 / 5555653
adult205 / 1939121105
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor22 / 119369184
germ cell tumor66 / 263845250
glioma3 / 10688328
head and neck tumor38 / 136302278
kidney tumor1 / 6895914
leukemia12 / 95842125
liver tumor6 / 9635962
lung tumor20 / 103127193
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal370 / 3360307110
ovarian tumor7 / 7668291
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer6 / 10268058
retinoblastoma15 / 46356323
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites18 / 40015449
bladder0 / 297570 
blood17 / 123478137
bone6 / 7165583
bone marrow1 / 4880120
brain221 / 1100989200
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye30 / 211054142
heart8 / 8962689
intestine20 / 23447285
kidney19 / 21177789
larynx0 / 241450 
liver8 / 20774338
lung31 / 33697491
lymph0 / 442700 
lymph node1 / 9161010
mammary gland8 / 15327152
mouth25 / 67052372
muscle3 / 10771527
nerve1 / 1576863
ovary10 / 10205197
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta17 / 28082560
prostate16 / 18934584
salivary gland12 / 20155595
skin11 / 21057452
spleen7 / 53952129
stomach4 / 9661941
testis60 / 330442181
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea18 / 52413343
umbilical cord2 / 13680146
uterus17 / 23287872
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214667_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.8
Adipocyte24.25
AdrenalCortex16.6
Adrenalgland12.3
Amygdala23.75
Appendix12.7
AtrioventricularNode10.95
BDCA4+_DentriticCells16.7
Bonemarrow17.2
BronchialEpithelialCells13.05
CD105+_Endothelial13.15
CD14+_Monocytes13.05
CD19+_BCells(neg._sel.)13.8
CD33+_Myeloid15.3
CD34+12.95
CD4+_Tcells11.8
CD56+_NKCells12.6
CD71+_EarlyErythroid13.5
CD8+_Tcells11.05
CardiacMyocytes75.05
Caudatenucleus12.3
Cerebellum25.55
CerebellumPeduncles26.7
CiliaryGanglion9.9
CingulateCortex16
Colorectaladenocarcinoma23.35
DorsalRootGanglion9.45
FetalThyroid18.75
Fetalbrain31.15
Fetalliver16.2
Fetallung9.85
GlobusPallidus11.9
Heart38.25
Hypothalamus13.75
Kidney14.25
Leukemia_chronicMyelogenousK-56213.85
Leukemia_promyelocytic-HL-6012
Leukemialymphoblastic(MOLT-4)11.05
Liver23.8
Lung21.1
Lymphnode12.9
Lymphoma_burkitts(Daudi)18.6
Lymphoma_burkitts(Raji)39.7
MedullaOblongata13.85
OccipitalLobe17
OlfactoryBulb10.35
Ovary12.25
Pancreas10.45
PancreaticIslet17.35
ParietalLobe24.55
Pituitary20.9
Placenta13.65
Pons15.85
PrefrontalCortex18.1
Prostate16.95
Salivarygland10.6
SkeletalMuscle26.75
Skin10.4
SmoothMuscle36.3
Spinalcord15
SubthalamicNucleus15.1
SuperiorCervicalGanglion20.1
TemporalLobe19.15
Testis13.6
TestisGermCell19.45
TestisIntersitial9.6
TestisLeydigCell17.65
TestisSeminiferousTubule12.8
Thalamus16.7
Thymus10.1
Thyroid23.3
Tongue14.1
Tonsil15.05
Trachea15.65
TrigeminalGanglion13.35
Uterus10.9
UterusCorpus14.6
WholeBlood22.1
Wholebrain13.55
colon20
pineal_day14.32
pineal_night14.72
retina21.825
small_intestine17.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P160969
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.59 ± 0.89
Basal Forebrain3.95 ± 0.93
Basal Part of Pons3.58 ± 0.52
Cerebellar Cortex4.96 ± 0.28
Cerebellar Nuclei3.64 ± 0.6
Claustrum4.31 ± 0.45
Epithalamus4.36 ± 1.07
Frontal Lobe3.9 ± 0.93
Globus Pallidus3.41 ± 0.67
Hypothalamus4.46 ± 0.43
Insula4.78 ± 0.73
Limbic Lobe4.54 ± 0.9
Mesencephalon4.16 ± 0.79
Myelencephalon4.25 ± 0.91
Occipital Lobe4.22 ± 0.91
Parietal Lobe4.2 ± 0.94
Pontine Tegmentum4.26 ± 1.08
Striatum2.57 ± 0.78
Subthalamus4.31 ± 0.16
Temporal Lobe4.82 ± 0.72
Thalamus3.93 ± 1.02
White Matter2.95 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trp53i11CBCerebellum14.59
18.26
Trp53i11CTXCerebral cortex24.79
24.41
Trp53i11HIPHippocampal region15.24
26.54
Trp53i11HPFHippocampal formation15.77
22.89
Trp53i11HYHypothalamus13.55
13.57
Trp53i11LSXLateral septal complex10.64
10.95
Trp53i11MBMidbrain12.87
13.28
Trp53i11MYMedulla7.58
8.29
Trp53i11OLFOlfactory bulb39.02
47.69
Trp53i11PPons9.91
9.91
Trp53i11PALPallidum9.42
10.76
Trp53i11RHPRetrohippocampal region16.56
19.24
Trp53i11sAMYStriatum-like amygdalar nuclei23.69
22.82
Trp53i11STRStriatum8.04
7.69
Trp53i11STRdStriatum dorsal region5.02
5.24
Trp53i11STRvStriatum ventral region8.02
6.06
Trp53i11THThalamus7.81
10.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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