AutismKB 2.0

Annotation Detail for ENTPD3


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Basic Information Top
Gene Symbol:ENTPD3 ( CD39L3,FLJ93839,HB6,NTPDase-3 )
Gene Full Name: ectonucleoside triphosphate diphosphohydrolase 3
Band: 3p22.1
Quick LinksEntrez ID:956; OMIM: 603161; Uniprot ID:ENTP3_HUMAN; ENSEMBL ID: ENSG00000168032; HGNC ID: 3365
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal41 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx1 / 2414541
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth2 / 6705229
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206191_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte5.05
AdrenalCortex5.15
Adrenalgland4.25
Amygdala15.75
Appendix10
AtrioventricularNode5.05
BDCA4+_DentriticCells4.9
Bonemarrow6.35
BronchialEpithelialCells30.75
CD105+_Endothelial4.7
CD14+_Monocytes4.8
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.9
CD34+5.9
CD4+_Tcells4.8
CD56+_NKCells5.75
CD71+_EarlyErythroid4.25
CD8+_Tcells4.3
CardiacMyocytes6.4
Caudatenucleus73.1
Cerebellum4.5
CerebellumPeduncles8.15
CiliaryGanglion3.95
CingulateCortex5.65
Colorectaladenocarcinoma5.15
DorsalRootGanglion7.15
FetalThyroid4.95
Fetalbrain5.05
Fetalliver4.4
Fetallung4.1
GlobusPallidus5.85
Heart6.75
Hypothalamus18.5
Kidney4.55
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)3.8
Liver7.6
Lung6.35
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)6.8
MedullaOblongata24.65
OccipitalLobe5.45
OlfactoryBulb3.85
Ovary3.5
Pancreas5.4
PancreaticIslet47.9
ParietalLobe8
Pituitary6.05
Placenta5.05
Pons9.5
PrefrontalCortex15
Prostate7.9
Salivarygland5.05
SkeletalMuscle5.65
Skin3.95
SmoothMuscle5.4
Spinalcord6.35
SubthalamicNucleus4.75
SuperiorCervicalGanglion23.2
TemporalLobe6.1
Testis4.5
TestisGermCell4.25
TestisIntersitial5.55
TestisLeydigCell5.2
TestisSeminiferousTubule4.4
Thalamus14.55
Thymus4.05
Thyroid10.5
Tongue8.4
Tonsil4.9
Trachea22.85
TrigeminalGanglion7.05
Uterus6.65
UterusCorpus5.45
WholeBlood5.1
Wholebrain13.6
colon4.9
pineal_day5.76
pineal_night5.74
retina7.775
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P29697
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.45 ± 0.78
Basal Forebrain4.54 ± 0.58
Basal Part of Pons5.09 ± 0.38
Cerebellar Cortex3.56 ± 0.53
Cerebellar Nuclei4.52 ± 0.7
Claustrum3.42 ± 0.62
Epithalamus3.24 ± 1.15
Frontal Lobe4.05 ± 0.64
Globus Pallidus3.67 ± 1.02
Hypothalamus4.27 ± 0.59
Insula4.13 ± 0.6
Limbic Lobe4.17 ± 0.7
Mesencephalon4.45 ± 0.67
Myelencephalon4.09 ± 0.85
Occipital Lobe4.47 ± 0.66
Parietal Lobe4.31 ± 0.64
Pontine Tegmentum4 ± 0.91
Striatum6.27 ± 0.67
Subthalamus4.41 ± 0.14
Temporal Lobe4.02 ± 0.66
Thalamus3.97 ± 0.7
White Matter2.06 ± 1.06
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Entpd3CBCerebellum4.83
6.05
Entpd3CTXCerebral cortex5.9
4.65
Entpd3HIPHippocampal region3.59
3.23
Entpd3HPFHippocampal formation4.97
4.02
Entpd3HYHypothalamus4.82
3.82
Entpd3LSXLateral septal complex0.94
0.72
Entpd3MBMidbrain10.37
10.78
Entpd3MYMedulla20.46
28.53
Entpd3OLFOlfactory bulb6.99
5.39
Entpd3PPons16.57
22.23
Entpd3PALPallidum9.59
9.24
Entpd3RHPRetrohippocampal region8.17
5.61
Entpd3sAMYStriatum-like amygdalar nuclei8.96
6.82
Entpd3STRStriatum12.66
9.15
Entpd3STRdStriatum dorsal region14.51
10.18
Entpd3STRvStriatum ventral region16.72
12.44
Entpd3THThalamus9.04
7.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018